Structural basis of the alternating-access mechanism in a bile acid transporter (Q27680833)

1

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Elena J Levin

2

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Yaping Pan

3

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Jason G McCoy

4

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Ruchika Sharma

5

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Brian Kloss

6

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Renato Bruni

7

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Matthias Quick

8

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Ming Zhou

Arginine oscillation explains Na+ independence in the substrate/product antiporter CaiT

9

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language of work or name

English

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publication date

23 January 2014

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published in

Nature

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volume

505

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page(s)

569-73

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issue

7484

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cites work

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Crystal structure of a bacterial homologue of glucose transporters GLUT1-4

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Crystal structure of an asymmetric trimer of a bacterial glutamate transporter homolog

20 March 2017

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Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT

20 March 2017

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Structure of a fucose transporter in an outward-open conformation

20 March 2017

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Transport mechanism of a bacterial homologue of glutamate transporters.

20 March 2017

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Crystal structure of a bacterial homologue of the kidney urea transporter

20 March 2017

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Molecular basis of transport and regulation in the Na(+)/betaine symporter BetP

20 March 2017

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20 March 2017

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Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

20 March 2017

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Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system

20 March 2017

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Towards automated crystallographic structure refinement with phenix.refine

20 March 2017

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20 March 2017

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Likelihood-enhanced fast rotation functions

20 March 2017

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Bile acid transporters: structure, function, regulation and pathophysiological implications

20 March 2017

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Use of non-crystallographic symmetry in protein structure refinement

20 March 2017

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Role of the intestinal bile acid transporters in bile acid and drug disposition

20 March 2017

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Crystal structure of a substrate-free aspartate transporter

20 March 2017

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Crystallizing membrane proteins using lipidic mesophases

22 April 2017

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Identification of new, well-populated amino-acid sidechain rotamers involving hydroxyl-hydrogen atoms and sulfhydryl-hydrogen atoms

7 April 2017

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Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

7 April 2017

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Structure of a glutamate transporter homologue from Pyrococcus horikoshii

7 April 2017

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The solute carrier family 10 (SLC10): beyond bile acid transport

24 May 2017

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The SLC10 carrier family: transport functions and molecular structure

29 September 2017

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The New York Consortium on Membrane Protein Structure (NYCOMPS): a high-throughput platform for structural genomics of integral membrane proteins

29 September 2017

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Inhibition of intestinal absorption of cholesterol by ezetimibe or bile acids by SC-435 alters lipoprotein metabolism and extends the lifespan of SR-BI/apoE double knockout mice

29 September 2017

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Monitoring the function of membrane transport proteins in detergent-solubilized form

29 September 2017

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Bile acid reabsorption inhibitors (BARI): novel hypolipidemic drugs

29 September 2017

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Structure of a Na+/H+ antiporter and insights into mechanism of action and regulation by pH.

29 September 2017

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Simple Allosteric Model for Membrane Pumps

29 September 2017

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1-[4-[4[(4R,5R)-3,3-Dibutyl-7-(dimethylamino)-2,3,4,5-tetrahydro-4-hydroxy-1,1-dioxido-1-benzothiepin-5-yl]phenoxy]butyl]-4-aza-1-azoniabicyclo[2.2.2]octane methanesulfonate (SC-435), an ileal apical sodium-codependent bile acid transporter inhibito

29 September 2017

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Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes.

21 January 2018

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Increased acyclovir oral bioavailability via a bile acid conjugate

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE12811

The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site

21 January 2018

1 reference

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Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter.

21 January 2018

1 reference

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HOLLOW: generating accurate representations of channel and interior surfaces in molecular structures

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24317697

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inability of diffusion to account for placental glucose transfer in the sheep and consideration of the kinetics of a possible carrier transfer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24317697

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE12811

1 reference

Dimensions Publication ID

2261275

1012333186

0 references

2261275

1 reference

1 reference

1 reference