MR1 presents microbial vitamin B metabolites to MAIT cells (Q27682747)

7-hydroxy-6-methyl-8-(1-D-ribityl)lumazine

ChEBI release 2020-05-28

ChEBI ID

17601

1 reference

reduced 6-(hydroxymethyl)-8-(1-D-ribityl)lumazine

ChEBI release 2020-05-28

ChEBI ID

27581

1 reference

ChEBI release 2020-05-28

19

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Lars Kjer-Nielsen

1

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James McCluskey

20

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Jérôme Le Nours

4

Jérôme Le Nours

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Bronwyn S Meehan

Bronwyn Meehan

5

0 references

Lyudmila Kostenko

Lyudmila Kostenko

9

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Alexandra J. Corbett

Alexandra J Corbett

3

0 references

George N. Khairallah

George N Khairallah

16

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Nicholas A. Williamson

Nicholas A Williamson

11

0 references

David P. Fairlie

David P Fairlie

18

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Anthony W. Purcell

Anthony W Purcell

12

0 references

Ligong Liu

Ligong Liu

6

0 references

Dale I Godfrey

Dale I Godfrey

17

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author name string

Onisha Patel

2

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Mugdha Bhati

7

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Zhenjun Chen

8

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Rangsima Reantragoon

10

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Nadine L Dudek

13

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Malcolm J McConville

14

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Richard A J O'Hair

Human mucosal associated invariant T cells detect bacterially infected cells

15

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language of work or name

English

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publication date

29 November 2012

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published in

Nature

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volume

491

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issue

7426

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page(s)

717-23

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Antimicrobial activity of mucosal-associated invariant T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Where do MAIT cells fit in the family of unconventional T cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Mucosal-associated invariant T cells: unconventional development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Fighting infection with your MAITs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

21 January 2018

The biology of NKT cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Antigen recognition by CD1d-restricted NKT T cell receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

An invariant T cell receptor alpha chain defines a novel TAP-independent major histocompatibility complex class Ib-restricted alpha/beta T cell subpopulation in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Evidence for MR1 antigen presentation to mucosal-associated invariant T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Endogenous MHC-related protein 1 is transiently expressed on the plasma membrane in a conformation that activates mucosal-associated invariant T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Modulation of Valpha19 NKT cell immune responses by alpha-mannosyl ceramide derivatives consisting of a series of modified sphingosines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Ultraviolet photodegradation of folic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

The crystal structure of human CD1d with and without alpha-galactosylceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Structure of a Classical MHC Class I Molecule That Binds “Non-Classical” Ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Structure of the human class I histocompatibility antigen, HLA-A2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Specificity pockets for the side chains of peptide antigens in HLA-Aw68

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

The fidelity, occasional promiscuity, and versatility of T cell receptor recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Interactions between the microbiota and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Structure, function and diversity of the healthy human microbiome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Host-gut microbiota metabolic interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Coot: model-building tools for molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

LIGSITE: automatic and efficient detection of potential small molecule-binding sites in proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Biosynthesis of water-soluble vitamins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11605

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23051753