His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency of the Metallo- -Lactamase VIM-7 (Q27684253)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24913158%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

His224 alters the R2 drug binding site and Phe218 influences the catalytic efficiency of the metallo-β-lactamase VIM-7 (English)

1 reference

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20 March 2020

7

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20 March 2020

Hanna-Kirsti S Leiros

object named as

Hanna-Kirsti S Leiros

1

1 reference

ORCID Public Data File 2021

author name string

Susann Skagseth

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24913158%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Kine Susann Waade Edvardsen

3

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20 March 2020

Marit Sjo Lorentzen

4

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20 March 2020

Gro Elin Kjæreng Bjerga

5

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20 March 2020

Ingar Leiros

6

1 reference

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20 March 2020

language of work or name

English

0 references

publication date

9 June 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24913158%20AND%20SRC:MED&resulttype=core&format=json

Antimicrobial Agents and Chemotherapy

20 March 2020

published in

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20 March 2020

volume

58

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20 March 2020

issue

8

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20 March 2020

page(s)

4826-4836

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"Stormy waters ahead": global emergence of carbapenemases

20 March 2020

cites work

1 reference

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Crystal Structures of Pseudomonas aeruginosa GIM-1: Active-Site Plasticity in Metallo- -Lactamases

20 March 2017

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Metallo-β-lactamases withstand low Zn(II) conditions by tuning metal-ligand interactions

20 March 2017

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Carbapenems: past, present, and future

20 March 2017

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Structural and computational investigations of VIM-7: insights into the substrate specificity of vim metallo-β-lactamases

20 March 2017

1 reference

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Crystal structure of NDM-1 reveals a common β-lactam hydrolysis mechanism

20 March 2017

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Biochemical and Structural Characterization of the Subclass B1 Metallo- -Lactamase VIM-4

20 March 2017

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20 March 2017

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Updated functional classification of beta-lactamases

20 March 2017

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The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form

20 March 2017

1 reference

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Structural basis for the role of Asp-120 in metallo-beta-lactamases

20 March 2017

1 reference

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Carbapenemases: the versatile beta-lactamases

20 March 2017

1 reference

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Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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The CCP4 suite: programs for protein crystallography

20 March 2017

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Identification of residues critical for metallo-beta-lactamase function by codon randomization and selection

20 March 2017

1 reference

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The ABCD's of β-lactamase nomenclature

20 March 2017

1 reference

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Proliferation and significance of clinically relevant β-lactamases

29 September 2017

1 reference

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Metallo-β-lactamase structure and function

29 September 2017

1 reference

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The emerging NDM carbapenemases

29 September 2017

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Epidemiological expansion, structural studies, and clinical challenges of new β-lactamases from gram-negative bacteria.

29 September 2017

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Metallo-β-lactamases: a last frontier for β-lactams?

29 September 2017

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Emerging carbapenemases: a global perspective

29 September 2017

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VIM-19, a metallo-beta-lactamase with increased carbapenemase activity from Escherichia coli and Klebsiella pneumoniae

29 September 2017

1 reference

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Diversity of beta-lactamases produced by ceftazidime-resistant Pseudomonas aeruginosa isolates causing bloodstream infections in Brazil

29 September 2017

1 reference

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The mechanisms of catalysis by metallo beta-lactamases

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136046

Enhancing the stability and solubility of TEV protease using in silico design

29 September 2017

1 reference

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Hydroxyl groups in the betabeta sandwich of metallo-beta-lactamases favor enzyme activity: Tyr218 and Ser262 pull down the lid.

29 September 2017

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Improved solubility of TEV protease by directed evolution

29 September 2017

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Metallo-beta-lactamases: the quiet before the storm?

29 September 2017

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Impact of remote mutations on metallo-beta-lactamase substrate specificity: implications for the evolution of antibiotic resistance

29 September 2017

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Update of the standard numbering scheme for class B beta-lactamases

29 September 2017

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blaVIM-7, an evolutionarily distinct metallo-beta-lactamase gene in a Pseudomonas aeruginosa isolate from the United States

29 September 2017

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Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family

29 September 2017

1 reference

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Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-beta-lactamase

2 June 2018

1 reference

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Characterization of the active-site residues asparagine 167 and lysine 161 of the IMP-1 metallo beta-lactamase.

2 June 2018

1 reference

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In vivo and in vitro characterization of TEV protease mutants.

2 June 2018

1 reference

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Thermodynamic analysis of ligand-induced changes in protein thermal unfolding applied to high-throughput determination of ligand affinities with extrinsic fluorescent dyes.

27 November 2018

1 reference

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Comment on: role of changes in the L3 loop of the active site in the evolution of enzymatic activity of VIM-type metallo-β-lactamases.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136046

Role of changes in the L3 loop of the active site in the evolution of enzymatic activity of VIM-type metallo-beta-lactamases

27 November 2018

1 reference

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Mutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta-lactamase from Aeromonas hydrophila

27 November 2018

1 reference

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Antibiotic recognition by binuclear metallo-beta-lactamases revealed by X-ray crystallography

27 November 2018

1 reference

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Hydroxyl groups in the (beta)beta sandwich of metallo-beta-lactamases favor enzyme activity: a computational protein design study

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136046

Probing the role of Asp-120(81) of metallo-beta-lactamase (IMP-1) by site-directed mutagenesis, kinetic studies, and X-ray crystallography

27 November 2018

1 reference

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Structural determinants of substrate binding to Bacillus cereus metallo-beta-lactamase

27 November 2018

1 reference

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Metal binding Asp-120 in metallo-beta-lactamase L1 from Stenotrophomonas maltophilia plays a crucial role in catalysis.

27 November 2018

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Mutational analysis of metallo-beta-lactamase CcrA from Bacteroides fragilis

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24913158

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.02735-13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24913158%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24913158%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference