The XMAP215 family drives microtubule polymerization using a structurally diverse TOG array (Q27684463)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966168%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Kevin C. Slep

5

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10 June 2020

author name string

Jaime C Fox

1

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10 June 2020

Amy E Howard

2

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10 June 2020

Stephen L Rogers

4

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Molecular Biology of the Cell

10 June 2020

publication date

15 August 2014

0 references

published in

1 reference

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10 June 2020

volume

25

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10 June 2020

issue

16

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10 June 2020

page(s)

2375-2392

1 reference

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describes a project that uses

10 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4142611/fullTextXML

inferred from PubMed Central ID database lookup

cites work

A cryptic TOG domain with a distinct architecture underlies CLASP-dependent bipolar spindle formation

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Dissecting the nanoscale distributions and functions of microtubule-end-binding proteins EB1 and ch-TOG in interphase HeLa cells

20 March 2017

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A TOG: -tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase

20 March 2017

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A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end

20 March 2017

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EBs Recognize a Nucleotide-Dependent Structural Cap at Growing Microtubule Ends

20 March 2017

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SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase

20 March 2017

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20 March 2017

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The lattice as allosteric effector: Structural studies of - and -tubulin clarify the role of GTP in microtubule assembly

20 March 2017

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Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1

20 March 2017

1 reference

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Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding

20 March 2017

1 reference

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Refined structure of alpha beta-tubulin at 3.5 A resolution

20 March 2017

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Electrostatics of nanosystems: application to microtubules and the ribosome

20 March 2017

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Structure of the alpha beta tubulin dimer by electron crystallography

20 March 2017

1 reference

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Features and development of Coot

20 March 2017

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Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast

20 March 2017

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Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels

20 March 2017

1 reference

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Microtubule polymerization dynamics

20 March 2017

1 reference

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Comparison of ARM and HEAT protein repeats

20 March 2017

1 reference

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Fission yeast Alp14 is a dose-dependent plus end-tracking microtubule polymerase

7 April 2017

1 reference

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The microtubule lattice and plus-end association of Drosophila Mini spindles is spatially regulated to fine-tune microtubule dynamics.

29 September 2017

1 reference

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Regulation of microtubule dynamics by TOG-domain proteins XMAP215/Dis1 and CLASP.

29 September 2017

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EB1 promotes microtubule dynamics by recruiting Sentin in Drosophila cells.

29 September 2017

1 reference

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GTPgammaS microtubules mimic the growing microtubule end structure recognized by end-binding proteins (EBs).

29 September 2017

1 reference

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XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region

29 September 2017

1 reference

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The role of TOG domains in microtubule plus end dynamics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

Advances and pitfalls of protein structural alignment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

XMAP215-EB1 interaction is required for proper spindle assembly and chromosome segregation in Xenopus egg extract

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

Culture of Drosophila S2 cells and their use for RNAi-mediated loss-of-function studies and immunofluorescence microscopy

29 September 2017

1 reference

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XMAP215 is a processive microtubule polymerase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

Assembly dynamics of microtubules at molecular resolution

29 September 2017

1 reference

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Stu2p binds tubulin and undergoes an open-to-closed conformational change

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

Mini spindles, the XMAP215 homologue, suppresses pausing of interphase microtubules in Drosophila.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

MAPping the eukaryotic tree of life: structure, function, and evolution of the MAP215/Dis1 family of microtubule-associated proteins

29 September 2017

1 reference

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Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle

29 September 2017

1 reference

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MOR1 is essential for organizing cortical microtubules in plants.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

XMAP215 regulates microtubule dynamics through two distinct domains.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts

29 September 2017

1 reference

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mini spindles: A gene encoding a conserved microtubule-associated protein required for the integrity of the mitotic spindle in Drosophila

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

XMAP from Xenopus eggs promotes rapid plus end assembly of microtubules and rapid microtubule polymer turnover.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

Ndc80 internal loop interacts with Dis1/TOG to ensure proper kinetochore-spindle attachment in fission yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

The TOGp protein is a new human microtubule-associated protein homologous to the Xenopus XMAP215.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142611

TOGp regulates microtubule assembly and density during mitosis and contributes to chromosome directional instability.

2 June 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-08-0501

MOR1, the Arabidopsis thaliana homologue of Xenopus MAP215, promotes rapid growth and shrinkage, and suppresses the pausing of microtubules in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-08-0501

Crystallization of a fragment of human fibronectin: introduction of methionine by site-directed mutagenesis to allow phasing via selenomethionine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-08-0501

The N-terminal TOG domain of Arabidopsis MOR1 modulates affinity for microtubule polymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-08-0501

Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-08-0501

XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-08-0501

The interaction of TOGp with microtubules and tubulin

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24966168

12 December 2020

inferred from PubMed ID database lookup

αβ-Tubulin and microtubule-binding assays

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24966168

12 December 2020

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24966168

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1091/MBC.E13-08-0501

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966168%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966168%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

24966168

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966168%20AND%20SRC:MED&resulttype=core&format=json