Anti-platelet therapy: phosphodiesterase inhibitors (Q27687228)

Stefania Momi

series ordinal

2

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Emanuela Falcinelli

series ordinal

3

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language of work or name

English

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publication date

October 2011

1 reference

British Journal of Clinical Pharmacology

published in

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volume

72

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issue

4

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page(s)

634-46

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Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second [...]

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RACTS: a prospective randomized antiplatelet trial of cilostazol versus ticlopidine in patients undergoing coronary stenting: long-term clinical and angiographic outcome

20 March 2017

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Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates

20 March 2017

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Managing PAD with multiple platelet inhibitors: the effect of combination therapy on bleeding time

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Antithrombotic therapy in patients with mechanical and biological prosthetic heart valves

20 March 2017

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Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

20 March 2017

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Cyclic GMP-dependent vasodilatory properties of LASSBio 294 in rat aorta

20 March 2017

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Fractionation and characterization of a cyclic adenine ribonucleotide formed by tissue particles

20 March 2017

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Drug interactions with phosphodiesterase-5 inhibitors used for the treatment of erectile dysfunction or pulmonary hypertension

20 March 2017

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Addition of cilostazol to aspirin and a thienopyridine for prevention of restenosis after coronary artery stenting: a meta-analysis

29 September 2017

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Population pharmacokinetic analysis of cilostazol in healthy subjects with genetic polymorphisms of CYP3A5, CYP2C19 and ABCB1.

29 September 2017

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Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway

29 September 2017

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Stroke prevention by cilostazol in patients with atherothrombosis: meta-analysis of placebo-controlled randomized trials

29 September 2017

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Potentiation and priming of platelet activation: a potential target for antiplatelet therapy

29 September 2017

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Dipyridamole, cerebrovascular disease, and the vasculature

29 September 2017

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Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack

29 September 2017

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Translational therapeutics of dipyridamole

29 September 2017

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Effects of anagrelide on megakaryopoiesis and platelet production

29 September 2017

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Atherosclerotic Vascular Disease Conference: Executive summary: Atherosclerotic Vascular Disease Conference proceeding for healthcare professionals from a special writing group of the American Heart Association

29 September 2017

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The pharmacology of cilostazol

29 September 2017

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Pharmacology of phosphodiesterase-5 inhibitors.

29 September 2017

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Antithrombotic therapy in peripheral arterial occlusive disease

29 September 2017

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Cyclic nucleotides and phosphodiesterases in platelets

29 September 2017

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29 September 2017

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Use of sildenafil (Viagra) in patients with cardiovascular disease. Technology and Practice Executive Committee

29 September 2017

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Mechanism of action of dipyridamole

29 September 2017

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A1- and A2-selective adenosine antagonists: in vivo characterization of cardiovascular effects

29 September 2017

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Anagrelide: A New Drug for Treating Thrombocytosis

29 September 2017

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Dipyridamole alone or combined with low-dose acetylsalicylic acid inhibits platelet aggregation in human whole blood ex vivo

29 September 2017

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Cardiovascular effects of milrinone

29 September 2017

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Human blood platelet 3': 5'-cyclic nucleotide phosphodiesterase. Isolation of low-Km and high-Km phosphodiesterase

29 September 2017

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Methods for the economic and quality of life supplement to the cilostazol for RESTenosis (CREST) trial

29 September 2017

1 reference

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Pharmacokinetics of multiple-dose oral cilostazol in middle-age and elderly men and women

2 June 2018

1 reference

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Activation of cGMP-stimulated phosphodiesterase by nitroprusside limits cAMP accumulation in human platelets: effects on platelet aggregation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195739

European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195739

Protection of low density lipoprotein oxidation at chemical and cellular level by the antioxidant drug dipyridamole

2 June 2018

1 reference

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Dipyridamole enhances interleukin-1beta-stimulated nitric oxide production by cultured rat vascular smooth muscle cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195739

The influence on platelet aggregation of drugs that affect the accumulation of adenosine 3':5'-cyclic monophosphate in platelets

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195739

Effect of a pyrimido-pyrimidine compound on platelet behaviour in vitro and in vivo.

2 June 2018

1 reference

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Effect of cilostazol on platelet aggregation and experimental thrombosis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195739

The metabolism of a new antithrombotic and vasodilating agent, cilostazol, in rat, dog and man.

2 June 2018

1 reference

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Effect of cilostazol on experimental cerebral infarction in rabbits

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195739

Platelet resistance to prostacyclin. Enhancement of the antiaggregatory effect of prostacyclin by pentoxifylline.

2 June 2018

1 reference

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Mechanism of the antiplatelet action of dipyridamole in whole blood: modulation of adenosine concentration and activity.

2 June 2018

1 reference

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Purification and characterization of a human platelet cyclic nucleotide phosphodiesterase

19 June 2018

1 reference

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Novel thienylacylhydrazone derivatives inhibit platelet aggregation through cyclic nucleotides modulation and thromboxane A2 synthesis inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Phosphodiesterase 2 mediates redox-sensitive endothelial cell proliferation and angiogenesis by thrombin via Rac1 and NADPH oxidase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Phosphodiesterase 4 inhibitor regulates the TRANCE/OPG ratio via COX-2 expression in a manner similar to PTH in osteoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Inhibition of platelet aggregation and the release of P-selectin from platelets by cilostazol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Adding cilostazol to dual antiplatelet therapy achieves greater platelet inhibition than high maintenance dose clopidogrel in patients with acute myocardial infarction: Results of the adjunctive cilostazol versus high maintenance dose clopidogrel in

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Cilostazol augments the inhibition of platelet aggregation in clopidogrel low-responders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Recovery of platelet function after withdrawal of cilostazol administered orally for a long period

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Cilostazol, a cAMP phosphodiesterase inhibitor, attenuates the production of monocyte chemoattractant protein-1 in response to tumor necrosis factor-alpha in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Evaluation of anti-platelet and anti-thrombotic effects of cilostazol with PFA-100® and Multiplate® whole blood aggregometer in vitro, ex vivo and FeCl3-induced thrombosis models in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Meta-analysis of results from eight randomized, placebo-controlled trials on the effect of cilostazol on patients with intermittent claudication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Effect of cilostazol on treadmill walking, community-based walking ability, and health-related quality of life in patients with intermittent claudication due to peripheral arterial disease: meta-analysis of six randomized controlled trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Cilostazol in addition to aspirin and clopidogrel improves long-term outcomes after percutaneous coronary intervention in patients with acute coronary syndromes: a randomized, controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Multicenter randomized trial evaluating the efficacy of cilostazol on ischemic vascular complications after drug-eluting stent implantation for coronary heart disease: results of the CILON-T (influence of CILostazol-based triple antiplatelet therapy

21 January 2018

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Periprocedural cilostazol treatment and restenosis after carotid artery stenting: the Retrospective Study of In-Stent Restenosis after Carotid Artery Stenting (ReSISteR-CAS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Cilostazol reduces restenosis after carotid artery stenting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Dipyridamole enhances NO/cGMP-mediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: in vitro and in vivo/ex vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Near-field amplification of antithrombotic effects of dipyridamole through vessel wall cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Aspirin plus dipyridamole versus aspirin for prevention of vascular events after stroke or TIA: a meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

The effect of Sildenafil on human platelet secretory function is controlled by a complex interplay between phosphodiesterases 2, 3 and 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Modulation of human platelet aggregation by the phosphodiesterase type 5 inhibitor sildenafil

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

The effect of sildenafil on human vascular function, platelet activation, and myocardial ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Phosphodiesterase inhibitors for pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Effects of tadalafil on platelets and endothelium in patients with erectile dysfunction and cardiovascular risk factors: a pilot study

21 January 2018

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PROLONGING PROSTACYCLIN PRODUCTION BY NAFAZATROM OR DIPYRIDAMOLE

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

COMBINING ANTIPLATELET AGENTS: POTENTIATION BETWEEN ASPIRIN AND DIPYRIDAMOLE

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2011.04034.X

Differential regulation of human platelet responses by cGMP inhibited and stimulated cAMP phosphodiesterases.

21 January 2018

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Dipyridamole inhibits platelet aggregation in whole blood

27 November 2018

1 reference

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Partial isolation and function of the prostacyclin regulating plasma factor

27 November 2018

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Relationship between vessel wall 13-HODE synthesis and vessel wall thrombogenicity following injury: influence of salicylate and dipyridamole treatment

27 November 2018

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12 December 2020

Antiaggregatory effect of oral cilostazol and recovery of platelet aggregability in patients with cerebrovascular disease

1 reference

12 December 2020

Caffeine alters A2A adenosine receptors and their function in human platelets

1 reference

12 December 2020

Inhibition of exercise-induced asthma by an orally absorbed mast cell stabilizer (M & B 22,948)

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12 December 2020

Potentiation of anti-platelet aggregating activity of cilostazol with vascular endothelial cells

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12 December 2020

Anti-aggregatory effects of physiological concentrations of adenosine in human whole blood as assessed by filtragometry

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12 December 2020

Synthesis and antiplatelet evaluation of novel aryl-sulfonamide derivatives, from natural safrole

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12 December 2020

Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro

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12 December 2020

Accumulation of radiolabelled platelets and fibrin on the carotid artery of rabbits after angioplasty: effects of heparin and dipyridamole

1 reference

12 December 2020

Effects of anagrelide on platelet cAMP levels, cAMP-dependent protein kinase and thrombin-induced Ca++ fluxes

1 reference

12 December 2020

Comparison of the inhibitory effects of cilostazol, acetylsalicylic acid and ticlopidine on platelet functions ex vivo. Randomized, double-blind cross-over study

1 reference

12 December 2020

Interplay between milrinone and adenosine in the inhibition of human platelet response

1 reference

12 December 2020

Increased platelet aggregability in response to shear stress in acute myocardial infarction and its inhibition by combined therapy with aspirin and cilostazol after coronary intervention

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12 December 2020

Inhibition and reversal of platelet aggregation by methyl xanthines

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12 December 2020

Effect of milrinone in human platelet shape change, aggregation and thromboxane A2 synthesis: an in vitro study

1 reference

12 December 2020

Dipyridamole inhibits leukotriene B4 synthesis

1 reference

12 December 2020

Comparison of the effects of acetylsalicylic acid, ticlopidine and cilostazol on primary hemostasis using a quantitative bleeding time test apparatus

1 reference

12 December 2020

Dipyridamole inhibits platelet aggregation induced by oxygen-derived free radicals

1 reference

12 December 2020

Aspirin and dipyridamole in the prevention of restenosis after percutaneous transluminal coronary angioplasty

1 reference

12 December 2020

Cilostazol stroke prevention study: A placebo-controlled double-blind trial for secondary prevention of cerebral infarction

1 reference

12 December 2020

Effect of antioxidants on chemiluminescence produced by reactive oxygen species

1 reference

12 December 2020

Effect of dipyridamole alone and in combination with aspirin on whole blood platelet aggregation, PGI2 generation, and red cell deformability ex vivo in man

1 reference

12 December 2020

Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta

1 reference

12 December 2020

Inhibition of shear stress-induced platelet aggregation by cilostazol, a specific inhibitor of cGMP-inhibited phosphodiesterase, in vitro and ex vivo

1 reference

12 December 2020

Dipyridamole inhibition of adenosine metabolism in human blood

1 reference

12 December 2020

Antiplatelet activity of dipyridamole in non anticoagulated whole blood

1 reference

12 December 2020

Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP

1 reference

12 December 2020

1 reference

12 December 2020

Effect of cilostazol, a phosphodiesterase III inhibitor, on experimental thrombosis in the porcine carotid artery

1 reference

12 December 2020

Dipyridamole potentiates the anti-aggregating effect of endothelium-derived relaxing factor

1 reference

12 December 2020

Aspirin extrusion from human platelets through multidrug resistance protein-4-mediated transport: evidence of a reduced drug action in patients after coronary artery bypass grafting

1 reference

12 December 2020

Effect of pentoxifylline on platelet aggregation

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12 December 2020

Adenosine 3',5'-phosphate in biological materials. I. Purification and properties of cyclic 3',5'-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3',5'-phosphate in human urine

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12 December 2020

A cold start for oral glycoprotein IIb/IIIa antagonists

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12 December 2020

Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice

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12 December 2020

Cilostazol pharmacokinetics after single and multiple oral doses in healthy males and patients with intermittent claudication resulting from peripheral arterial disease

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12 December 2020

10.1111/J.1365-2125.2011.04034.X

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

21649691

1 reference