Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action (Q27690642)

Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment

21 April 2017

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Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria

21 April 2017

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Electron transfer by domain movement in cytochrome bc1

21 April 2017

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Possible molecular mechanisms of the protonmotive function of cytochrome systems

21 April 2017

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Structure of the yeast cytochrome bc1 complex with a hydroxyquinone anion Qo site inhibitor bound

21 April 2017

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Structure of complex III with bound cytochrome c in reduced state and definition of a minimal core interface for electron transfer

21 April 2017

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Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c

21 April 2017

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Conformational Toggling of Yeast Iso-1-Cytochrome c in the Oxidized and Reduced States

21 April 2017

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A comparison of stigmatellin conformations, free and bound to the photosynthetic reaction center and the cytochrome bc1 complex

21 April 2017

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PROSITE, a protein domain database for functional characterization and annotation

21 April 2017

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Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

21 April 2017

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21 April 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 April 2017

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Features and development of Coot

21 April 2017

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PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

21 April 2017

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Overview of the CCP4 suite and current developments

21 April 2017

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UCSF Chimera--a visualization system for exploratory research and analysis

21 April 2017

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NCBI Reference Sequences (RefSeq): current status, new features and genome annotation policy

21 April 2017

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https://api.crossref.org/works/10.1038%2FNCOMMS5029

CD-HIT: accelerated for clustering the next-generation sequencing data

21 April 2017

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https://api.crossref.org/works/10.1038%2FNCOMMS5029

Drug-resistant malaria: molecular mechanisms and implications for public health

21 April 2017

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https://api.crossref.org/works/10.1038%2FNCOMMS5029

Preventing malaria in travellers

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS5029

A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Atovaquone - a novel broad-spectrum anti-infective drug.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Design of anti-parasitic and anti-fungal hydroxy-naphthoquinones that are less susceptible to drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

A structural perspective on mechanism and function of the cytochrome bc (1) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Inhibiting Plasmodium cytochrome bc1: a complex issue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Molecular basis for atovaquone binding to the cytochrome bc1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Acridinediones: selective and potent inhibitors of the malaria parasite mitochondrial bc1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Quinolone-3-diarylethers: a new class of antimalarial drug.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Modeling the molecular basis of atovaquone resistance in parasites and pathogenic fungi

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS5029

Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS5029

Antimalarial pharmacology and therapeutics of atovaquone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Re-examination of inhibitor resistance conferred by Qo-site mutations in cytochrome b using yeast as a model system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Molecular basis of resistance to cytochrome bc1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Cytochrome b mutations that modify the ubiquinol-binding pocket of the cytochrome bc1 complex and confer anti-malarial drug resistance in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Transforming rhinacanthin analogues from potent anticancer agents into potent antimalarial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Inhibition of electron transfer in the cytochrome b-c, segment of the mitochondrial respiratory chain by a synthetic analogue of ubiquinone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Hidden Markov model speed heuristic and iterative HMM search procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Pneumocystis carinii cytochrome b mutations are associated with atovaquone exposure in patients with AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Recapitulation in Saccharomyces cerevisiae of cytochrome b mutations conferring resistance to atovaquone in Pneumocystis jiroveci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

A graphical user interface to the CCP4 program suite

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Probing the Role of E272 in Quinol Oxidation of Mitochondrial Complex III†

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Mutational Analysis of Cytochrome b at the Ubiquinol Oxidation Site of Yeast Complex III

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

Atovaquone-proguanil for treating uncomplicated malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

7 January 2021

Efficacy of atovaquone in treatment of toxoplasmosis in patients with AIDS. The NIAID-Clinical Center Intramural AIDS Program

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

7 January 2021

Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3- hydroxy-1,4-naphthoquinone (566C80)

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

7 January 2021

A mechanism for the synergistic antimalarial action of atovaquone and proguanil

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

7 January 2021

Atovaquone, a broad spectrum antiparasitic drug, collapses mitochondrial membrane potential in a malarial parasite

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

7 January 2021

Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

7 January 2021

Naphthoquinone antimalarials; general survey

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

7 January 2021

Potentiometric studies on yeast complex III

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

7 January 2021

Determination of the redox properties of the Rieske [2Fe-2S] cluster of bovine heart bc1 complex by direct electrochemistry of a water-soluble fragment

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5029

7 January 2021

Identifiers

DOI

10.1038/NCOMMS5029

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1565334

ADS bibcode

2014NatCo...5.4029B

0 references

1027281151

0 references

1565334

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference