Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives (Q27690772)

language of work or name

English

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publication date

April 2014

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1 reference

146

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issue

4

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page(s)

914-28

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The genetics of complex cholestatic disorders

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Genetic basis of susceptibility to drug-induced liver injury: what have we learned and where do we go from here?

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Frequency, clinical presentation, and outcomes of drug-induced liver injury after liver transplantation.

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The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

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Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure

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The role of hepatitis E virus testing in drug-induced liver injury.

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Searching for a needle in a haystack: use of ICD-9-CM codes in drug-induced liver injury

29 September 2017

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29 September 2017

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29 September 2017

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Detection of apoptotic caspase activation in sera from patients with chronic HCV infection is associated with fibrotic liver injury

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Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States

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29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

The development of in vitro culture methods to characterize primary T-cell responses to drugs

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Polymerase γ gene POLG determines the risk of sodium valproate-induced liver toxicity

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Cytokine and autoantibody patterns in acute liver failure

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Acetylation rates and monthly liver function tests during one year of isoniazid preventive therapy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

HLA haplotype determines hapten or p-i T cell reactivity to flucloxacillin.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Incidence, presentation, and outcomes in patients with drug-induced liver injury in the general population of Iceland.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

HLA-B*5701 and flucloxacillin associated drug-induced liver disease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

The effects of heparins on the liver: application of mechanistic serum biomarkers in a randomized study in healthy volunteers.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Quantitative analyses and transcriptomic profiling of circulating messenger RNAs as biomarkers of rat liver injury

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

A role for the pregnane X receptor in flucloxacillin-induced liver injury.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Use of pharmaco-metabonomics for early prediction of acetaminophen-induced hepatotoxicity in humans

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Drug-induced liver injury in Japan: An analysis of 1676 cases between 1997 and 2006.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

The long-term follow-up after idiosyncratic drug-induced liver injury with jaundice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: search for signals

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Serum apoptosis markers in acute liver failure: a pilot study.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

The impact of eosinophilia and hepatic necrosis on prognosis in patients with drug-induced liver injury

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Measurement of serum acetaminophen-protein adducts in patients with acute liver failure

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Drug-induced liver injury: summary of a single topic clinical research conference

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Detection of autoantibody to aldolase B in sera from patients with troglitazone-induced liver dysfunction

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Incidence of drug-induced liver injury in medical inpatients.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

The burden of acute nonfulminant drug-induced hepatitis in a United States tertiary referral center [corrected].

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Descriptive epidemiology of acute liver enzyme abnormalities in the general population of central Massachusetts

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031195

Drug-induced liver injury

27 November 2018

1 reference

12 December 2020

Liver regeneration in acute severe liver impairment: a clinicopathological correlation study

1 reference

12 December 2020

Hepatic glycogenosis: an underrecognized source of abnormal liver function tests?

1 reference

12 December 2020

High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury

1 reference

12 December 2020

Efficacy and safety of high-dose pravastatin in hypercholesterolemic patients with well-compensated chronic liver disease: Results of a prospective, randomized, double-blind, placebo-controlled, multicenter trial

1 reference

12 December 2020

Tamoxifen inhibits topoisomerases, depletes mitochondrial DNA, and triggers steatosis in mouse liver

1 reference

12 December 2020

Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis

1 reference

12 December 2020

Role of Toll-like receptors in HMGB1 release from macrophages

1 reference

12 December 2020

Approaches to the Study of Drug-Induced Liver Injury

1 reference

12 December 2020

Understanding the role of reactive metabolites in drug-induced hepatotoxicity: state of the science

1 reference

12 December 2020

Circulating microRNAs as potential markers of human drug-induced liver injury

1 reference

12 December 2020

Avoiding idiosyncratic DILI: two is better than one

1 reference

12 December 2020