Structural basis for the inhibition of the eukaryotic ribosome (Q27695601)

1

0 references

Irina Prokhorova

2

0 references

Wolf Holtkamp

3

0 references

Gulnara Yusupova

5

0 references

Marat Yusupov

Inhibition, by selected antibiotics, of protein synthesis in cells growing in tissue cultures

6

0 references

language of work or name

English

0 references

publication date

25 September 2014

0 references

published in

Nature

0 references

volume

513

0 references

issue

7519

0 references

page(s)

517-22

0 references

cites work

1 reference

12 December 2020

Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system

1 reference

12 December 2020

U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:

1 reference

12 December 2020

Cycloheximide resistance in yeast: the gene and its portein

1 reference

12 December 2020

Omacetaxine mepesuccinate in the treatment of intractable chronic myeloid leukemia

1 reference

12 December 2020

Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling

1 reference

12 December 2020

Features and development of Coot

1 reference

12 December 2020

Eukaryotic ribosomal RNA determinants of aminoglycoside resistance and their role in translational fidelity.

1 reference

12 December 2020

One core, two shells: bacterial and eukaryotic ribosomes.

1 reference

12 December 2020

Inhibitors of protein biosynthesis. II. Mode of action of anisomycin

1 reference

12 December 2020

Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome

1 reference

12 December 2020

4′-O-substitutions determine selectivity of aminoglycoside antibiotics

1 reference

12 December 2020

Location of resistance to the alkaloid narciclasine in the 60S ribosomal subunit.

1 reference

12 December 2020

Molecular mechanisms of deoxynivalenol resistance in the yeastSaccharomyces cerevisiae.

1 reference

12 December 2020

Narciclasine: an antitumour alkaloid which blocks peptide bond formation by eukaryotic ribosomes

1 reference

12 December 2020

The CRY1 gene in Chlamydomonas reinhardtii: structure and use as a dominant selectable marker for nuclear transformation

1 reference

12 December 2020

Biological evaluation of structurally diverse amaryllidaceae alkaloids and their synthetic derivatives: discovery of novel leads for anticancer drug design

1 reference

12 December 2020

Cryptopleurine--an inhibitor of translocation

1 reference

12 December 2020

Selection of tRNA by the ribosome requires a transition from an open to a closed form

1 reference

12 December 2020

Inhibition of protein synthesis by blasticidin S. I. Studies with cell-free systems from bacterial and mammalian cells

1 reference

12 December 2020

Basis for prokaryotic specificity of action of aminoglycoside antibiotics

1 reference

12 December 2020

The translation of translational control by FMRP: therapeutic targets for FXS.

1 reference

12 December 2020

Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against Leishmania and Trypanosoma

1 reference

12 December 2020

Mechanism of Inhibition of Eukaryotic Protein Synthesis by Trichothecene Fungal Toxins

1 reference

12 December 2020

Alkaloid homoharringtonine inhibits polypeptide chain elongation on human ribosomes on the step of peptide bond formation

1 reference

12 December 2020

Protein synthesis inhibition by 8-oxo-12,13-epoxytrichothecenes

1 reference

12 December 2020

Binding of T-2 toxin to eukaryotic cell ribosomes

1 reference

12 December 2020

Affinities of tRNA binding sites of ribosomes from Escherichia coli.

1 reference

12 December 2020

Natural cycloheximide resistance in yeast. The role of ribosomal protein L41.

1 reference

12 December 2020

Designer aminoglycosides that selectively inhibit cytoplasmic rather than mitochondrial ribosomes show decreased ototoxicity: a strategy for the treatment of genetic diseases

1 reference

12 December 2020

Fluorescent Derivatives of Yeast tRNAPhe

1 reference

12 December 2020

Isolation and characterization of Saccharomyces cerevisiae mutants resistant to T-2 toxin

1 reference

12 December 2020

A new understanding of the decoding principle on the ribosome

1 reference

12 December 2020

Migration of 40 S ribosomal subunits on messenger RNA in the presence of edeine

1 reference

12 December 2020

Simultaneous ribosomal resistance to trichodermin and anisomycin in Saccharomyces cerevisiae mutants

1 reference

12 December 2020

Drastic alteration of cycloheximide sensitivity by substitution of one amino acid in the L41 ribosomal protein of yeasts

1 reference

12 December 2020

Inhibitors of protein synthesis in eukarytic cells. Comparative effects of some amaryllidaceae alkaloids

1 reference

12 December 2020

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

1 reference

12 December 2020

Trichothecenes: from simple to complex mycotoxins

1 reference

12 December 2020

Inhibition of Translation in Eukaryotic Systems by Harringtonine

1 reference

12 December 2020

Optimal fine φ-slicing for single-photon-counting pixel detectors

1 reference

12 December 2020

Design at the atomic level: generation of novel hybrid biaryloxazolidinones as promising new antibiotics

1 reference

12 December 2020

Structures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula marismortui

1 reference

12 December 2020

Molecular genetics of cryptopleurine resistance in Saccharomyces cerevisiae: expression of a ribosomal protein gene family.

1 reference

12 December 2020

Crystal structure of the eukaryotic 60S ribosomal subunit in complex with initiation factor 6

1 reference

12 December 2020

The structure of the eukaryotic ribosome at 3.0 Å resolution

1 reference

12 December 2020

Aminoglycoside antibiotics in the 21st century.

1 reference

12 December 2020

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

12 December 2020

The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit

1 reference

12 December 2020

Binding of [3H]narciclasine to eukaryotic ribosomes A study on a structure-activity relationship

1 reference

12 December 2020

Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes

1 reference

12 December 2020

Eukaryotic protein synthesis inhibitors identified by comparison of cytotoxicity profiles

1 reference

12 December 2020

Crystal structure of the 80S yeast ribosome

1 reference

12 December 2020

Retrieval of crystallographically-derived molecular geometry information.

1 reference

12 December 2020

Ribosomal resistance to the 12,13-epoxytrichothecene antibiotics in the producing organism Myrothecium verrucaria

1 reference

12 December 2020

Dissecting the ribosomal inhibition mechanisms of edeine and pactamycin: the universally conserved residues G693 and C795 regulate P-site RNA binding

1 reference

12 December 2020

The comparative RNA web (CRW) site: an online database of comparative sequence and structure information for ribosomal, intron, and other RNAs

1 reference

12 December 2020

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

1 reference

12 December 2020

Ribosome-targeting antibiotics and mechanisms of bacterial resistance.

1 reference

12 December 2020

Nucleotide sequence of the tcml gene (ribosomal protein L3) of Saccharomyces cerevisiae

1 reference

12 December 2020

Methylation of ribosomal protein L42 regulates ribosomal function and stress-adapted cell growth

1 reference

12 December 2020

A new system for naming ribosomal proteins

1 reference

12 December 2020

Quantitation of the specific interaction of [14a-3H]cryptopleurine with 80S and 40S ribosomal species from the yeast Saccharomyces cerevisiae.

1 reference

12 December 2020

Genetics and biochemistry of cryptopleurine resistance in the yeast Saccharomyces cerevisiae

1 reference

12 December 2020

Mechanisms of action of aminoglycoside antibiotics in eucaryotic protein synthesis

1 reference

12 December 2020

Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution

1 reference

12 December 2020

rRNA modifications and ribosome function

1 reference

12 December 2020

Elements of ribosomal drug resistance and specificity.

1 reference

12 December 2020

1 reference

12 December 2020

Peptidyltransferase center of ribosomes. On the mechanism of action of alkaloid lycorine

1 reference

12 December 2020

Sense from nonsense: therapies for premature stop codon diseases.

1 reference

12 December 2020

Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.

1 reference

12 December 2020

Biosynthetic studies and genetic engineering of pactamycin analogs with improved selectivity toward malarial parasites.

1 reference

12 December 2020

Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state

1 reference

12 December 2020

Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit

1 reference

12 December 2020

PubChem: Integrated Platform of Small Molecules and Biological Activities

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE13737

7 January 2021