The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design (Q27732214)

5

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David Ian Stuart

object named as

D Stuart

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author name string

R Esnouf

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A Hopkins

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C Ross

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D Stammers

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

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publication date

15 September 1995

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published in

Structure

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volume

3

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issue

9

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page(s)

915-26

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cites work

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Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1

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Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

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High resolution structures of HIV-1 RT from four RT-inhibitor complexes

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Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

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The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1

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Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution

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Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors

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HIV‐1‐specific RT inhibitors: Highly selective inhibitors of human immunodeficiency virus type 1 that are specifically targeted at the viral reverse transcriptase

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Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor

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Crystals of HIV-1 Reverse Transcriptase Diffracting to 2·2 Å Resolution

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Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 1. Tricyclic pyridobenzo- and dipyridodiazepinones

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Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of alpha-anilinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase

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Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative

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Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors.

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Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

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PROCHECK: a program to check the stereochemical quality of protein structures

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Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase

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Structure of ribonuclease H phased at 2 A resolution by MAD analysis of the selenomethionyl protein

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Crystal structure of Escherichia coli RNase HI in complex with Mg2+ at 2.8 A resolution: proof for a single Mg(2+)-binding site

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Non-nucleoside inhibitors of HIV-1 reverse transcriptase: molecular modeling and x-ray structure investigations

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Crystal structure of nevirapine, a non-nucleoside inhibitor of HIV-1 reverse transcriptase, and computational alignment with a structurally diverse inhibitor

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Interactions between drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase

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