Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents (Q27734207)

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A M Stevens

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J K Gierse

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J J McDonald

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R A Stegeman

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J Y Pak

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D Gildehaus

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J M Miyashiro

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T D Penning

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K Seibert

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P C Isakson

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W C Stallings

Prostaglandin endoperoxide synthases-1 and -2.

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language of work or name

English

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publication date

December 1996

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384

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issue

6610

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page(s)

644-8

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cites work

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7 January 2021

Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation

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7 January 2021

Prostaglandin synthase 2.

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7 January 2021

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

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7 January 2021

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic

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7 January 2021

The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

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7 January 2021

The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase

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7 January 2021

Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site

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7 January 2021

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase

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7 January 2021

NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro

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7 January 2021

Tyrosyl radicals and their role in hydroperoxide-dependent activation and inactivation of prostaglandin endoperoxide synthase

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7 January 2021

Higher oxidation states of prostaglandin H synthase. Rapid electronic spectroscopy detected two spectral intermediates during the peroxidase reaction with prostaglandin G2

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7 January 2021

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

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7 January 2021

Structure and conformation of the cis and trans isomers of 1-(p-chlorobenzylidene)-2-methyl-5-methoxyindenylacetic acid

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7 January 2021

A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.

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7 January 2021

Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.

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7 January 2021

Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase

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7 January 2021

Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase

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7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

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7 January 2021

Identifiers

DOI

10.1038/384644A0

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1942556

1012843708

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1942556

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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