Flexibility in DNA recombination: structure of the lambda integrase catalytic core (Q27735010)

1

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R Tirumalai

2

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A Landy

3

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T Ellenberger

Structure and mechanism of DNA topoisomerase II

4

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language of work or name

English

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publication date

4 April 1997

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published in

Science

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volume

276

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issue

5309

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page(s)

126-31

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cites work

1 reference

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Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I

20 March 2017

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Refinement of gamma delta resolvase reveals a strikingly flexible molecule

20 March 2017

1 reference

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Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration

20 March 2017

1 reference

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Crystal structure of the site-specific recombinase gamma delta resolvase complexed with a 34 bp cleavage site

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

High-resolution structure of the catalytic domain of avian sarcoma virus integrase

20 March 2017

1 reference

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Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

20 March 2017

1 reference

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ALSCRIPT: a tool to format multiple sequence alignments

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Protein structure comparison by alignment of distance matrices

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

FLP recombinase of the 2 microns circle plasmid of Saccharomyces cerevisiae bends its DNA target. Isolation of FLP mutants defective in DNA bending

20 March 2017

1 reference

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Catalysis by site-specific recombinases

20 March 2017

1 reference

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The Cre recombinase cleaves the lox site in trans

20 March 2017

1 reference

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Dynamic, structural, and regulatory aspects of lambda site-specific recombination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Coupling of local folding to site-specific binding of proteins to DNA

20 March 2017

1 reference

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Crystal structure of cyclin-dependent kinase 2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Site-specific genetic recombination: hops, flips, and flops.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Mechanistic and structural complexity in the site-specific recombination pathways of Int and FLP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Complementation of bacteriophage lambda integrase mutants: evidence for an intersubunit active site.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Directed protein replacement in recombination full sites reveals trans-horizontal DNA cleavage by Flp recombinase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Lambda integrase cleaves DNA in cis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Xer site-specific recombination in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Gatecrashers at the catalytic party

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Patterns of lambda Int recognition in the regions of strand exchange

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

The mechanism of conservative site-specific recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Step-arrest mutants of FLP recombinase: implications for the catalytic mechanism of DNA recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

X-ray structure of the DNase I-d(GGTATACC)2 complex at 2.3 A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

The bacteriophage lambda int gene product. A filter assay for genetic recombination, purification of int, and specific binding to DNA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Autonomous DNA binding domains of lambda integrase recognize two different sequence families

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Excision and insertion of the conjugative transposon Tn916 involves a novel recombination mechanism

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Identification of the active site tyrosine of Flp recombinase. Possible relevance of its location to the mechanism of recombination

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Evidence for a second conserved arginine residue in the integrase family of recombination proteins

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Sequence requirements for target activity in site-specific recombination mediated by the Int protein of transposon Tn 1545.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Improvement of macromolecular electron-density maps by the simultaneous application of real and reciprocal space constraints.

19 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Mapping the functional domains of bacteriophage lambda integrase protein

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Interaction of the NH2- and COOH-terminal domains of the FLP recombinase with the FLP recognition target sequence.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Site-specific recombination systems of phages phi 80 and P22: binding sites of integration host factor and recombination-induced mutations.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

Role for DNA homology in site-specific recombination. The isolation and characterization of a site affinity mutant of coliphage lambda

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839824

[25] Protein multiple sequence alignment and flexible pattern matching

27 November 2018

1 reference

12 December 2020

DNA cleavage in trans by the active site tyrosine during Flp recombination: Switching protein partners before exchanging strands

1 reference

12 December 2020

The crystal structure of the catalytic domain of the site-specific recombination enzyme gamma delta resolvase at 2.7 A resolution

1 reference

12 December 2020

Suicide recombination substrates yield covalent lambda integrase-DNA complexes and lead to identification of the active site tyrosine

1 reference

12 December 2020

Asymmetry in active complexes of FLP recombinase

1 reference

12 December 2020

Binding and cleavage of nicked substrates by site-specific recombinases XerC and XerD

1 reference

12 December 2020

Cis and trans in site-specific recombination

1 reference

12 December 2020

Identifying determinants of recombination specificity: construction and characterization of mutant bacteriophage integrases

1 reference

12 December 2020