Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7 (Q27748910)

Oncogenic point mutations in the human retinoblastoma gene: their application to genetic counseling

21 January 2018

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A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding

21 January 2018

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Oncogenic point mutations in exon 20 of the RB1 gene in families showing incomplete penetrance and mild expression of the retinoblastoma phenotype

21 January 2018

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The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

21 January 2018

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Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene.

21 January 2018

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Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

21 January 2018

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Identification of a growth suppression domain within the retinoblastoma gene product

21 January 2018

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The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

21 January 2018

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Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

21 January 2018

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The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

21 January 2018

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The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

21 January 2018

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E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product

21 January 2018

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Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

21 January 2018

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Mechanism of active transcriptional repression by the retinoblastoma protein

21 January 2018

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A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

21 January 2018

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Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product

21 January 2018

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SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

21 January 2018

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Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

21 January 2018

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Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis

21 January 2018

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Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product

21 January 2018

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Domains A and B in the Rb pocket interact to form a transcriptional repressor motif

21 January 2018

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21 January 2018

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Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107.

21 January 2018

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Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

21 January 2018

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Crystal structure of a TFIIB-TBP-TATA-element ternary complex

21 January 2018

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A maize cDNA encoding a member of the retinoblastoma protein family: involvement in endoreduplication

21 January 2018

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The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus

21 January 2018

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Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

21 January 2018

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Identification of distinct roles for separate E1A domains in disruption of E2F complexes

21 January 2018

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Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes

21 January 2018

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Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

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A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

21 January 2018

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7 January 2021

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

1 reference

7 January 2021

Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene.

1 reference

7 January 2021

Both conserved region 1 (CR1) and CR2 of the human papillomavirus type 16 E7 oncogene are required for induction of epidermal hyperplasia and tumor formation in transgenic mice

1 reference

7 January 2021

The human papillomavirus E7 oncoprotein and the cellular transcription factor E2F bind to separate sites on the retinoblastoma tumor suppressor protein.

1 reference

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

7 January 2021