The structural basis of hammerhead ribozyme self-cleavage (Q27748930)

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L Maloney

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A Karpeisky

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N Usman

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L Beigelman

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W G Scott

The global conformation of an active hammerhead RNA during the process of self-cleavage

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language of work or name

English

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publication date

6 March 1998

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published in

Cell

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volume

92

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issue

5

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page(s)

665-73

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cites work

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Ion-induced folding of the hammerhead ribozyme: a fluorescence resonance energy transfer study

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Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase

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Role of divalent metal ions in the hammerhead RNA cleavage reaction

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Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism

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Inhibition of the hammerhead ribozyme cleavage reaction by site-specific binding of Tb

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The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

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Evidence for a hydroxide ion bridging two magnesium ions at the active site of the hammerhead ribozyme

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A kinetic and thermodynamic framework for the hammerhead ribozyme reaction

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Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding

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Freeze trapping of reaction intermediates

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Processing of X-ray diffraction data collected in oscillation mode

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Hard and Soft Acids and Bases

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Three-dimensional structure of a hammerhead ribozyme

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Improved Fourier coefficients for maps using phases from partial structures with errors

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Ribozymes: structure and mechanism in RNA catalysis

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The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage

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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

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A conformational change in the catalytic core of the hammerhead ribozyme upon cleavage of an RNA substrate

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Configurationally defined phosphorothioate-containing oligoribonucleotides in the study of the mechanism of cleavage of hammerhead ribozymes

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A small catalytic oligoribonucleotide

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Two autolytic processing reactions of a satellite RNA proceed with inversion of configuration

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The intervening sequence RNA of Tetrahymena is an enzyme

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