Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue (Q27749065)

2

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M Kato

3

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T Shimizu

4

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M Shirakawa

5

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S Kuroda

6

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K Kaibuchi

7

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T Hakoshima

Journal of Biological Chemistry

8

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language of work or name

English

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publication date

17 April 1998

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published in

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volume

273

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issue

16

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page(s)

9656-66

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Identification of a putative target for Rho as the serine-threonine kinase protein kinase N

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Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells.

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Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form.

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Biological and biochemical properties of human rasH genes mutated at codon 61.

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The effector interactions of p21ras

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The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S

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Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

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Crystal structure of active elongation factor Tu reveals major domain rearrangements

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The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

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Glucosylation of Rho proteins by Clostridium difficile toxin B.

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Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1.

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Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine.

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Tertiary and quaternary structural changes in Gi alpha 1 induced by GTP hydrolysis

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Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.

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Ras/Rap effector specificity determined by charge reversal

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The Dbl family of oncogenes

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Direct involvement of the small GTP-binding protein Rho in lbc oncogene function

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Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

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Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

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C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases

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A modulator of rho family G proteins, rhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm

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Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

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Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis

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Phase combination and cross validation in iterated density-modification calculations

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Rac "insert region" is a novel effector region that is implicated in the activation of NADPH oxidase, but not PAK65

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The Dbl oncogene product as a GDP/GTP exchange protein for the Rho family: its properties in comparison with those of Smg GDS

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