X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin (Q27749608)

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11 November 2019

title

X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin (English)

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11 November 2019

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2

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11 November 2019

author name string

E Conti

series ordinal

1

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11 November 2019

A Wonacott

series ordinal

3

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11 November 2019

P Brick

series ordinal

4

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11 November 2019

language of work or name

English

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publication date

1 March 1998

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11 November 2019

number of pages

5

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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11 November 2019

volume

425

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11 November 2019

issue

2

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11 November 2019

page(s)

229-233

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The structure of a complex of recombinant hirudin and human alpha-thrombin

11 November 2019

cites work

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Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design

21 January 2018

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The interaction of thrombin with fibrinogen. A structural basis for its specificity

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The binding of proflavin to thrombin.

21 January 2018

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The optical detection of transients in trypsin- and chymotrypsin-catalyzed reactions

21 January 2018

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Physical evidence for an apolar binding site near the catalytic center of human α-thrombin

21 January 2018

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A novel one-step purification of human α-thrombin after direct activation of crude prothrombin enriched from plasma

21 January 2018

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Crystallographic R factor refinement by molecular dynamics

21 January 2018

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A graphics model building and refinement system for macromolecules

21 January 2018

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The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

21 January 2018

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The refined crystal structure of bovine beta-trypsin at 1.8 A resolution. II. Crystallographic refinement, calcium binding site, benzamidine binding site and active site at pH 7.0

21 January 2018

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On the size of the active site in proteases. I. Papain

21 January 2018

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

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On the interaction of the active side of alpha-chymotrypsin with chromophores: proflavin binding and enzyme conformation during catalysis

21 January 2018

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Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics

21 January 2018

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Proflavin binding within the fibrinopeptide groove adjacent to the catalytic site of human alpha-thrombin

21 January 2018

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Converting trypsin to chymotrypsin: ground-state binding does not determine substrate specificity

21 January 2018

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Activation of prothrombin with (taipan snake) venom

21 January 2018

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Are the structure and function of an enzyme the same in aqueous solution and in the wet crystal?

21 January 2018

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Thermodynamics of substrates and reversible inhibitors binding to the active site cleft of human alpha-thrombin

21 January 2018

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10.1016/S0014-5793(98)00235-X

21 January 2018

Identifiers

DOI

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11 November 2019

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