Specific p53 mutations predict poor prognosis in oral squamous cell carcinoma (Q27824790)

2

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Atsuko Hirai

3

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Chihiro Sugiura

4

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Ken-ichi Notani

5

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Haruhiko Kashiwazaki

6

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Kanchu Tei

7

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Yasunori Totsuka

8

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Hiroshi Fukuda

Oncogenic forms of p53 inhibit p53-regulated gene expression

9

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language of work or name

English

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publication date

February 2003

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published in

Oral Oncology

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volume

39

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issue

2

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page(s)

163-9

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cites work

1 reference

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

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Genetic alterations in patients with esophageal cancer with short- and long-term survival rates after curative esophagectomy.

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Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy

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7 January 2021

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

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Mutations in residues of TP53 that directly contact DNA predict poor outcome in human primary breast cancer

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Overexpression of bax associated with mutations in the loop-sheet-helix motif of p53

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TP53 DNA contact mutations are selectively associated with allelic loss and have a strong clinical impact in head and neck cancer

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p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma

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Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

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High frequency of p53 mutations in human oral epithelial dysplasia and primary squamous cell carcinoma detected by yeast functional assay

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Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

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Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

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An analysis of the prognostic significance of p53 status for squamous cell carcinoma of the oral cavity treated by radiotherapy

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p53 mutational spectra are different between squamous-cell carcinomas of the lip and the oral cavity

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10.1016/S1368-8375(02)00064-7

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

4787064

4787064

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference