The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary (Q27851576)

PubMed

PubMed publication ID

20693978

13 November 2016

title

The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary (English)

1 reference

PubMed

PubMed publication ID

13 November 2016

6

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author name string

Stacey Jamieson

1

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Ralf Butzow

2

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Noora Andersson

3

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Maria Alexiadis

4

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Leila Unkila-Kallio

5

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Peter J Fuller

7

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Mikko Anttonen

The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome

8

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publication date

November 2010

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published in

Modern Pathology

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volume

23

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issue

11

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page(s)

1477-85

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cites work

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The gonadotropin releasing hormone (GnRH) receptor activating sequence (GRAS) is a composite regulatory element that interacts with multiple classes of transcription factors including Smads, AP-1 and a forkhead DNA binding protein

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The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors

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Functional exploration of the adult ovarian granulosa cell tumor-associated somatic FOXL2 mutation p.Cys134Trp (c.402C>G).

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Extinction of FOXL2 expression in aggressive ovarian granulosa cell tumors in children.

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Expression status and mutational analysis of the ras and B-raf genes in ovarian granulosa cell and epithelial tumors.

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Expression, mutational analysis and in vitro response of imatinib mesylate and nilotinib target genes in ovarian granulosa cell tumors

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Transrepression of estrogen receptor beta signaling by nuclear factor-kappab in ovarian granulosa cells

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GATA-4 regulates Bcl-2 expression in ovarian granulosa cell tumors

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Establishment and characterization of a steroidogenic human granulosa-like tumor cell line, KGN, that expresses functional follicle-stimulating hormone receptor

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FOXL2 interacts with steroidogenic factor-1 (SF-1) and represses SF-1-induced CYP17 transcription in granulosa cells

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Inhibin Subunit Gene Expression in Ovarian Cancer

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Insulin-like growth factor, insulin-like growth factor?binding protein-4, and pregnancy-associated plasma protein-A gene expression in human granulosa cell tumors

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No Evidence of a Role for Mutations or Polymorphisms of the Follicle-Stimulating Hormone Receptor in Ovarian Granulosa Cell Tumors

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FSH-regulated gene expression profiles in ovarian tumours and normal ovaries

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7 January 2021

High GATA-4 expression associates with aggressive behavior, whereas low anti-Müllerian hormone expression associates with growth potential of ovarian granulosa cell tumors

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7 January 2021

Elevated serum inhibin concentrations in postmenopausal women with ovarian tumors

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7 January 2021

A prospective study of inhibin in granulosa cell tumors of the ovary

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7 January 2021

Mutational analysis of FOXL2 codon 134 in granulosa cell tumour of ovary and other human cancers

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7 January 2021