Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer (Q27851620)

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Expression of p16 and Retinoblastoma Determines Response to CDK4/6 Inhibition in Ovarian Cancer

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English	Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer	scientific article	Expression of p16 and Retinoblastoma Determines Response to CDK4/6 Inhibition in Ovarian Cancer

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scholarly article

1 reference

13 November 2016

Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer (English)

1 reference

13 November 2016

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

Victor Velculescu

15

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Charles Ginther

13

object named as

Charles Ginther

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6

object named as

Judy Dering

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Boris Winterhoff

object named as

Boris Winterhoff

2

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Meenal Chalukya

8

object named as

Meenal Chalukya

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Kanthinh Manivong

5

object named as

Kanthinh Manivong

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14

object named as

Siân Jones

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Lynn C. Hartmann

20

object named as

Lynn C Hartmann

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Kimberly R Kalli

11

object named as

Kimberly R Kalli

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Gottfried E Konecny

1

object named as

Gottfried E Konecny

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William A Cliby

17

object named as

William A Cliby

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21

object named as

Dennis J Slamon

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author name string

Teodora Kolarova

3

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Jingwei Qi

4

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Guorong Yang

7

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He-Jing Wang

9

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Lee Anderson

10

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Richard S Finn

12

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Darren Riehle

16

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Sophia Randolph

18

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Maria Koehler

19

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language of work or name

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publication date

15 March 2011

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Clinical Cancer Research

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17

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1591-602

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6

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Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

20 March 2017

PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

20 March 2017

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

20 March 2017

Identification of G1 kinase activity for cdk6, a novel cyclin D partner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

20 March 2017

The consensus coding sequences of human breast and colorectal cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

20 March 2017

Tumor suppression by Ink4a-Arf: progress and puzzles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

20 March 2017

Inactivation of p16/CDKN2 and p15/MTS2 is associated with prognosis and response to chemotherapy in ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

20 March 2017

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

20 March 2017

Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

29 September 2017

Activity of the multikinase inhibitor dasatinib against ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

29 September 2017

Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

29 September 2017

Cell cycle genes in ovarian cancer: steps toward earlier diagnosis and novel therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

29 September 2017

Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

29 September 2017

Cyclin D1, p53, and p21Waf1/Cip1 expression is predictive of poor clinical outcome in serous epithelial ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

29 September 2017

Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

29 September 2017

The Rb/E2F pathway: expanding roles and emerging paradigms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

29 September 2017

Cyclin D-CDK subunit arrangement is dependent on the availability of competing INK4 and p21 class inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

29 September 2017

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

29 September 2017

Characterization of chromosome 9 in human ovarian neoplasia identifies frequent genetic imbalance on 9q and rare alterations involving 9p, including CDKN2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

2 June 2018

A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

27 November 2018

Overexpression of Cdk6-cyclin D3 highly sensitizes cells to physical and chemical transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

27 November 2018

Inhibition of ras-induced proliferation and cellular transformation by p16INK4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598646

27 November 2018

Evidence of functional RB protein in epithelial ovarian carcinomas despite loss of heterozygosity at the RB locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21278246

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of heterozygosity at the RB-1 locus and pRB immunostaining in epithelial ovarian tumors: a molecular, immunohistochemical, and clinicopathologic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21278246

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/21278246

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of tumor suppressor gene p16 and prognosis of epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21278246

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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