Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial (Q27853001)

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scientific article published in June 2014

Language	Label	Description	Also known as
English	Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial	scientific article published in June 2014

Statements

scholarly article

1 reference

13 November 2016

Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial (English)

1 reference

13 November 2016

phase III clinical trial

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ado-trastuzumab emtansine

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Her2-receptor positive breast cancer

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1 reference

based on heuristic

inferred from title

author name string

Ian E Krop

1

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Sung-Bae Kim

2

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Antonio González-Martín

3

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Patricia M LoRusso

4

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Jean-Marc Ferrero

5

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Melanie Smitt

6

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Ron Yu

7

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Abraham C F Leung

8

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Hans Wildiers

9

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publication date

June 2014

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Lancet Oncology Commission

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15

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7

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689-99

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Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970178-0

7 January 2021

based on heuristic

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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970178-0

7 January 2021

based on heuristic

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Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group

1 reference

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Lapatinib plus capecitabine for HER2-positive advanced breast cancer

1 reference

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7 January 2021

based on heuristic

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Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a german breast group 26/breast international group 03-05 study.

1 reference

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7 January 2021

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Overall survival benefit with lapatinib in combination with trastuzumab for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: final results from the EGF104900 Study

1 reference

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7 January 2021

based on heuristic

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Overcoming resistance and restoring sensitivity to HER2-targeted therapies in breast cancer

1 reference

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7 January 2021

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Retreatment with trastuzumab-based therapy after disease progression following lapatinib in HER2-positive metastatic breast cancer

1 reference

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Trastuzumab and Gemcitabine in Pretreated HER2 Overexpressing Metastatic Breast Cancer Patients: Retrospective Analysis of Our Series

1 reference

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7 January 2021

based on heuristic

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Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Trastuzumab-DM1 (T-DM1) retains all the mechanisms of action of trastuzumab and efficiently inhibits growth of lapatinib insensitive breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970178-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Trastuzumab emtansine for HER2-positive advanced breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970178-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A phase II study of trastuzumab emtansine in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who were previously treated with trastuzumab, lapatinib, an anthracycline, a taxane, and capecitabine

1 reference

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7 January 2021

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New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

1 reference

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7 January 2021

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Randomized study of Lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Patient-reported outcomes from EMILIA, a randomized phase 3 study of trastuzumab emtansine (T-DM1) versus capecitabine and lapatinib in human epidermal growth factor receptor 2-positive locally advanced or metastatic breast cancer

1 reference

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7 January 2021

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A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

PI3K pathway activation results in low efficacy of both trastuzumab and lapatinib

1 reference

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7 January 2021

based on heuristic

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Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules

1 reference

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7 January 2021

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High-content live-cell imaging assay used to establish mechanism of trastuzumab emtansine (T-DM1)--mediated inhibition of platelet production

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970178-0

7 January 2021

based on heuristic

inferred from DOI database lookup

HER2 protein and gene variation between primary and metastatic breast cancer: significance and impact on patient care.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970178-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Stability of HER2-positive status in breast carcinoma: a comparison between primary and paired metastatic tumors with regard to the possible impact of intervening trastuzumab treatment.

1 reference

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7 January 2021

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inferred from DOI database lookup

Blinded independent central review of progression-free survival in phase III clinical trials: important design element or unnecessary expense?

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970178-0

7 January 2021

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inferred from DOI database lookup

Blinded independent central review of progression in cancer clinical trials: results from a meta-analysis

1 reference

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Evaluation of Blinded Independent Central Review of Tumor Progression in Oncology Clinical Trials: A Meta-analysis

1 reference

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Identifiers

10.1016/S1470-2045(14)70178-0

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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