Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. (Q27919645)

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Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts

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English	Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts.	scientific article	Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts

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26 November 2016

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20 December 2019

Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts (English)

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20 December 2019

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Thomas A Kunkel

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20 December 2019

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Zhigang Wang

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20 December 2019

Tong Zhou

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20 December 2019

Miguel Garcia-Diaz

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Luis Blanco

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Lawrence F Povirk

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Katarzyna Bebenek

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Jae Wan Lee

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15 October 2003

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20 December 2019

Journal of Biological Chemistry

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20 December 2019

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805-811

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20 December 2019

Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome

1 reference

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21 January 2018

Repair of a specific double-strand break generated within a mammalian chromosome by yeast endonuclease I-SceI.

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Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

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Accurate in vitro end joining of a DNA double strand break with partially cohesive 3'-overhangs and 3'-phosphoglycolate termini: effect of Ku on repair fidelity

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21 January 2018

Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction

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Mechanisms of overlap formation in nonhomologous DNA end joining

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21 January 2018

DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining

1 reference

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21 January 2018

Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair

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21 January 2018

Highly frequent frameshift DNA synthesis by human DNA polymerase mu

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The frameshift infidelity of human DNA polymerase lambda. Implications for function.

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Construction of a vector containing a site-specific DNA double-strand break with 3'-phosphoglycolate termini and analysis of the products of end-joining in CV-1 cells

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21 January 2018

Implication of DNA-dependent protein kinase in an early, essential, local phosphorylation event during end-joining of DNA double-strand breaks in vitro

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Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction

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DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells

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21 January 2018

DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis

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21 January 2018

DNA polymerase lambda, a novel DNA repair enzyme in human cells.

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In vitro repair of complex unligatable oxidatively induced DNA double-strand breaks by human cell extracts

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21 January 2018

DNA end-joining catalyzed by human cell-free extracts

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Two novel human and mouse DNA polymerases of the polX family

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DNA polymerase mu, a candidate hypermutase?

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A physical and functional interaction between yeast Pol4 and Dnl4-Lif1 links DNA synthesis and ligation in nonhomologous end joining

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Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation

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Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli

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Sorting the consequences of ionizing radiation: processing of 8-oxoguanine/abasic site lesions

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Regulation and mechanisms of mammalian double-strand break repair

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Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

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Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase

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Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks

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Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

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Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity

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Crystal structure of an Xrcc4-DNA ligase IV complex

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Crystal structure of the Xrcc4 DNA repair protein and implications for end joining

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Cutting edge: DNA polymerases mu and lambda are dispensable for Ig gene hypermutation

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Identifiers

10.1074/JBC.M307913200

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Europe PubMed Central

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20 December 2019

2 references

26 November 2016

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14561766%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

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