Multiple Nudix family proteins possess mRNA decapping activity (Q27930396)

7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activity

GOA release 2020-03-11

author

Megerditch Kiledjian

series ordinal

3

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author name string

Sophie Bail

series ordinal

2

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Man-Gen Song

series ordinal

1

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language of work or name

English

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publication date

March 2013

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1 reference

1 December 2016

19

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page(s)

390-9

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issue

3

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cites work

1 reference

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Multiple mRNA decapping enzymes in mammalian cells

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NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest

20 March 2017

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Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping

20 March 2017

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Mammalian enzymes for preventing transcriptional errors caused by oxidative damage

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Xenopus U8 snoRNA binding protein is a conserved nuclear decapping enzyme

20 March 2017

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Crystal structure of Dcp1p and its functional implications in mRNA decapping

20 March 2017

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DcpS can act in the 5'-3' mRNA decay pathway in addition to the 3'-5' pathway

20 March 2017

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Functional characterization of the mammalian mRNA decapping enzyme hDcp2

20 March 2017

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Poly(A)-binding proteins: multifunctional scaffolds for the post-transcriptional control of gene expression

20 March 2017

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Mammalian NADH diphosphatases of the Nudix family: cloning and characterization of the human peroxisomal NUDT12 protein

20 March 2017

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The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme

20 March 2017

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Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures

20 March 2017

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Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay

20 March 2017

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The hDcp2 protein is a mammalian mRNA decapping enzyme

20 March 2017

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The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases

20 March 2017

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The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family

20 March 2017

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eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

20 March 2017

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The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif

20 March 2017

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20 March 2017

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The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex

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20 March 2017

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Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2

20 March 2017

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NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals

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Mouse MTH2 protein which prevents mutations caused by 8-oxoguanine nucleotides

20 March 2017

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The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes

20 March 2017

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Eukaryotic mRNA decapping

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Starting at the beginning, middle, and end: translation initiation in eukaryotes

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A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation

7 April 2017

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Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure

7 April 2017

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Identification of cytoplasmic capping targets reveals a role for cap homeostasis in translation and mRNA stability

7 April 2017

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29 September 2017

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29 September 2017

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29 September 2017

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