The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation (Q27930884)

GOA release 2020-03-11

Ctr9p YOL145C

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GOA release 2020-03-11

author

Ali Shilatifard

12

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Mark Johnston

object named as

Mark Johnston

10

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Nevan Krogan

1

object named as

Nevan J Krogan

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Jack Greenblatt

11

object named as

Jack F Greenblatt

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author name string

Jim Dover

2

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Adam Wood

3

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Jessica Schneider

4

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Jonathan Heidt

5

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Marry Ann Boateng

6

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Kimberly Dean

7

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Owen W Ryan

8

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Ashkan Golshani

Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II

9

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language of work or name

English

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publication date

March 2003

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1 December 2016

11

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page(s)

721-9

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issue

3

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cites work

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Methylation of histone H3 Lys 4 in coding regions of active genes

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Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism

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Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae

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Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain

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General initiation factors for RNA polymerase II.

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Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6.

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dELL is an essential RNA polymerase II elongation factor with a general role in development

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Drosophila ELL is associated with actively elongating RNA polymerase II on transcriptionally active sites in vivo

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Identification of a decay in transcription potential that results in elongation factor dependence of RNA polymerase II.

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Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

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RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach

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COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression

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Identification, cloning, expression, and biochemical characterization of the testis-specific RNA polymerase II elongation factor ELL3

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7 January 2021

COMPASS: a complex of proteins associated with a trithorax-related SET domain protein

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7 January 2021

Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex

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7 January 2021

A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3

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7 January 2021

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

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Ubiquitination of histone H2B by Rad6 is required for efficient Dot1-mediated methylation of histone H3 lysine 79.

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SET1, a yeast member of the trithorax family, functions in transcriptional silencing and diverse cellular processes

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7 January 2021

The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins

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Exchange of RNA polymerase II initiation and elongation factors during gene expression in vivo

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The RNA polymerase II general elongation factors

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Rad6-dependent ubiquitination of histone H2B in yeast

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The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4

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7 January 2021

Active genes are tri-methylated at K4 of histone H3

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7 January 2021

Factors regulating the transcriptional elongation activity of RNA polymerase II

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An RNA polymerase II elongation factor encoded by the human ELL gene

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Mechanism and regulation of transcriptional elongation and termination by RNA polymerase II

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ELL2, a new member of an ELL family of RNA polymerase II elongation factors

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7 January 2021

The Paf1 complex physically and functionally associates with transcription elongation factors in vivo

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Identification of RTF1, a novel gene important for TATA site selection by TATA box-binding protein in Saccharomyces cerevisiae

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7 January 2021

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

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7 January 2021

Systematic genetic analysis with ordered arrays of yeast deletion mutants

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7 January 2021

Basic mechanisms of transcript elongation and its regulation

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7 January 2021

Dot1p modulates silencing in yeast by methylation of the nucleosome core

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7 January 2021

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

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7 January 2021

Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter

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Alteration of nucleosome structure as a mechanism of transcriptional regulation

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Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro

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7 January 2021