Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing (Q27933470)

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English	Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing	scientific article

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scholarly article

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PubMed publication ID

1 December 2016

Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing (English)

1 reference

PubMed publication ID

1 December 2016

1 reference

GOA release 2020-03-11

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A Moris

4

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author name string

D Xu

1

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D J Field

2

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S J Tang

3

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B P Bobechko

5

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J D Friesen

6

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language of work or name

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publication date

April 1998

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Molecular and Cellular Biology

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PubMed publication ID

1 December 2016

18

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4

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2055-66

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Evidence that U5 snRNP recognizes the 3' splice site for catalytic step II in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

20 March 2017

The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

20 March 2017

An RNA-dependent ATPase associated with U2/U6 snRNAs in pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

20 March 2017

CUS1, a suppressor of cold-sensitive U2 snRNA mutations, is a novel yeast splicing factor homologous to human SAP 145.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

20 March 2017

snRNA interactions at 5' and 3' splice sites monitored by photoactivated crosslinking in yeast spliceosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

20 March 2017

Mutational analysis of the PRP4 protein of Saccharomyces cerevisiae suggests domain structure and snRNP interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

20 March 2017

Prp16p, Slu7p, and Prp8p interact with the 3' splice site in two distinct stages during the second catalytic step of pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

20 March 2017

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

20 March 2017

A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

20 March 2017

Dynamic RNA-RNA interactions in the spliceosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

7 April 2017

Yeast mRNA splicing in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

7 April 2017

Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

7 April 2017

Prp43: An RNA helicase-like factor involved in spliceosome disassembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Trans-activation of group II intron splicing by nuclear U5 snRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Mutagenesis of the yeast gene PRP8 reveals domains governing the specificity and fidelity of 3' splice site selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

A U1/U4/U5 snRNP complex induced by a 2'-O-methyl-oligoribonucleotide complementary to U5 snRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Invariant U2 RNA sequences bordering the branchpoint recognition region are essential for interaction with yeast SF3a and SF3b subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Dynamic association of proteins with the pre-mRNA branch region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Randomization-selection analysis of snRNAs in vivo: evidence for a tertiary interaction in the spliceosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Branch nucleophile selection in pre-mRNA splicing: evidence for the bulged duplex model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Structurally related but functionally distinct yeast Sm D core small nuclear ribonucleoprotein particle proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Extensive interactions of PRP8 protein with the 5' and 3' splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

SLU7 and a novel activity, SSF1, act during the PRP16-dependent step of yeast pre-mRNA splicing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Characterization and functional ordering of Slu7p and Prp17p during the second step of pre-mRNA splicing in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

The phylogenetically predicted base-pairing interaction between alpha and alpha' is required for group II splicing in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Branch-point attack in group II introns is a highly reversible transesterification, providing a potential proofreading mechanism for 5'-splice site selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

An essential splicing factor, SLU7, mediates 3' splice site choice in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Evidence for a base-pairing interaction between U6 small nuclear RNA and 5' splice site during the splicing reaction in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

29 September 2017

Mutations within the yeast U4/U6 snRNP protein Prp4 affect a late stage of spliceosome assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

2 June 2018

Interactions of the yeast U6 RNA with the pre-mRNA branch site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

2 June 2018

Mutations in U6 snRNA that alter splice site specificity: implications for the active site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

2 June 2018

An element in human U6 RNA destabilizes the U4/U6 spliceosomal RNA complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

2 June 2018

Two domains of yeast U6 small nuclear RNA required for both steps of nuclear precursor messenger RNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

2 June 2018

Splice site selection and role of the lariat in a group II intron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

2 June 2018

Mutational analysis of the yeast U2 snRNA suggests a structural similarity to the catalytic core of group I introns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

2 June 2018

Synthetic lethal mutations suggest interactions between U5 small nuclear RNA and four proteins required for the second step of splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

2 June 2018

Requirement for SLU7 in yeast pre-mRNA splicing is dictated by the distance between the branchpoint and the 3' splice site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

27 November 2018

A mechanism to enhance mRNA splicing fidelity: the RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

27 November 2018

A novel role for a U5 snRNP protein in 3' splice site selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121436

27 November 2018

Evidence for an essential non-Watson–Crick interaction between the first and last nucleotides of a nuclear pre-mRNA intron

1 reference

https://pubmed.ncbi.nlm.nih.gov/9528778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Four yeast spliceosomal proteins (PRP5, PRP9, PRP11, and PRP21) interact to promote U2 snRNP binding to pre-mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/9528778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-specific cross-linking of mammalian U5 snRNP to the 5' splice site before the first step of pre-mRNA splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/9528778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The U5 and U6 small nuclear RNAs as active site components of the spliceosome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9528778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of U6 snRNA in 5' splice site selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9528778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functionally redundant interactions between U2 and U6 spliceosomal snRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/9528778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The invariant U5 snRNA loop 1 sequence is dispensable for the first catalytic step of pre-mRNA splicing in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/9528778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple exon-binding sites in class II self-splicing introns

1 reference

https://pubmed.ncbi.nlm.nih.gov/9528778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

U5 snRNA interacts with exon sequences at 5′ and 3′ splice sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/9528778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/9528778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.18.4.2055

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PMC publication ID

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PubMed publication ID

1 reference

PubMed publication ID

1 December 2016

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