Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway. (Q27933673)

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15 January 2020

title

Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway (English)

1 reference

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15 January 2020

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GOA release 2020-03-11

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3

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15 January 2020

5

Joshua LaBaer

1 reference

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15 January 2020

6

Stuart L Schreiber

1 reference

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15 January 2020

author name string

Rebecca A Butcher

series ordinal

1

1 reference

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15 January 2020

Bhupinder S Bhullar

series ordinal

2

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15 January 2020

Gerald Marsischky

series ordinal

4

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15 January 2020

language of work or name

English

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publication date

15 January 2006

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15 January 2020

published in

Nature Chemical Biology

2 references

1 December 2016

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15 January 2020

volume

2

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15 January 2020

issue

2

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15 January 2020

page(s)

103-109

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Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction

15 January 2020

cites work

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RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

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RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

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Tor signalling in bugs, brain and brawn

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Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae

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Dysregulation of the TSC-mTOR pathway in human disease

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Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips

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Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

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Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes

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Chemogenomic profiling: identifying the functional interactions of small molecules in yeast

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Targeted selection of recombinant clones through gene dosage effects

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A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR).

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7 January 2021

Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method.

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7 January 2021

Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways

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7 January 2021

GUF1, a gene encoding a novel evolutionarily conserved GTPase in budding yeast

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7 January 2021

Functional discovery via a compendium of expression profiles

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7 January 2021

Block of cyclic nucleotide-gated channels in salamander olfactory receptor neurons by the guanylyl cyclase inhibitor LY83583

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7 January 2021

LY-83583 stimulates glucose transporter-1-mediated glucose transport independent of changes in cGMP levels

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7 January 2021

CDD: a Conserved Domain Database for protein classification

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Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

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7 January 2021

Development and validation of a T7 based linear amplification for genomic DNA

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1038/NCHEMBIO762

2 references

Consolidated OpenCitations Corpus – April 2017

5009027

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16415861%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

15 January 2020

1047665950

0 references

5009027

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

5009027