A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery (Q27933727)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1902506

regulation of G2/M transition of mitotic cell cycle

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1902504

negative regulation of mitotic DNA damage checkpoint

1 reference

Gene Ontology release 2020-05-02

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Histone H2A YDR225W

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Transcription elongation factor SPT4 YGR063C

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Histone chaperone NAP1 YKR048C

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Phosphoprotein phosphatase PP4 catalytic subunit PPH3 YDR075W

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Psy4p YBL046W

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Transcription elongation factor SPT5 YML010W

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Erratum: Corrigendum: A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery

corrigendum / erratum

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12 July 2019

http://api.crossref.org/works?select=update-to&filter=doi:10.1038/NATURE04772

author

Daniel Durocher

15

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Stephen Buratowski

Michael-Christopher Keogh

13

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1

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Xuetong Shen

Xuetong Shen

12

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James E. Haber

James E Haber

14

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Andrew Emili

10

Andrew Emili

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Nevan Krogan

17

Nevan J Krogan

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Jack Greenblatt

16

Jack F Greenblatt

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author name string

Jung-Ae Kim

2

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Michael Downey

3

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Jeffrey Fillingham

4

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Dipanjan Chowdhury

5

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Jacob C Harrison

6

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Megumi Onishi

7

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Nira Datta

8

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Sarah Galicia

9

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Judy Lieberman

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

11

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language of work or name

English

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publication date

26 January 2006

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1 reference

1 December 2016

439

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issue

7075

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page(s)

497-501

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cites work

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A role for Saccharomyces cerevisiae histone H2A in DNA repair.

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Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break

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Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast

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DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

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Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair

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Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair.

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DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain

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gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

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Systematic genetic analysis with ordered arrays of yeast deletion mutants

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Mating-type gene switching in Saccharomyces cerevisiae

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Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

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Recovery from checkpoint-mediated arrest after repair of a double-strand break requires Srs2 helicase

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In vivo roles of Rad52, Rad54, and Rad55 proteins in Rad51-mediated recombination.

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Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions

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Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated

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Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage

21 January 2018

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The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage

21 January 2018

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Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

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A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

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PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break

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Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest.

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Loss of a yeast telomere: arrest, recovery, and chromosome loss.

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