The Saccharomyces cerevisiae YOR163w gene encodes a diadenosine 5', 5"'-P1,P6-hexaphosphate (Ap6A) hydrolase member of the MutT motif (Nudix hydrolase) family (Q27934558)

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Language	Label	Description	Also known as
English	The Saccharomyces cerevisiae YOR163w gene encodes a diadenosine 5', 5"'-P1,P6-hexaphosphate (Ap6A) hydrolase member of the MutT motif (Nudix hydrolase) family	scientific article

Statements

scholarly article

1 reference

PubMed publication ID

1 December 2016

The Saccharomyces cerevisiae YOR163w gene encodes a diadenosine 5', 5"'-P1,P6-hexaphosphate (Ap6A) hydrolase member of the MutT motif (Nudix hydrolase) family (English)

1 reference

PubMed publication ID

1 December 2016

Saccharomyces cerevisiae

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bis(5'-adenosyl)-pentaphosphatase activity

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Gene Ontology release 2020-05-02

Gene Ontology ID

bis(5'-adenosyl)-hexaphosphatase activity

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

Polyphosphatase DDP1 YOR163W

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GOA release 2020-03-11

author name string

J L Cartwright

1

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A G McLennan

2

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language of work or name

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publication date

26 March 1999

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Journal of Biological Chemistry

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PubMed publication ID

1 December 2016

274

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13

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8604-10

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Opposite effects of cell differentiation and apoptosis on Ap3A/Ap4A ratio in human cell cultures

1 reference

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21 January 2018

Presence of diadenosine 5',5''' -P1, P4-tetraphosphate (Ap4A) in mamalian cells in levels varying widely with proliferative activity of the tissue: a possible positive "pleiotypic activator"

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Diadenosine polyphosphates: Their biological and pharmacological significance

1 reference

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Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase

1 reference

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21 January 2018

Human diadenosine 5',5"'-P1,P4-tetraphosphate pyrophosphohydrolase is a member of the MutT family of nucleotide pyrophosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Sequencing and enhanced expression of the gene encoding diadenosine 5',5'''-P1, P4-tetraphosphate (Ap4A) phosphorylase in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Catabolism of bis(5'-nucleosidyl) tetraphosphates in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

The MutT motif-containing ORF163w protein from the yeast Saccharomyces cerevisiae encodes a (di)nucleoside polyphosphate hydrolase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

The action of a water-soluble carbodiimide on adenosine-5'-polyphosphates

1 reference

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21 January 2018

In vivo synthesis of adenylylated bis(5'-nucleosidyl) tetraphosphates (Ap4N) by Escherichia coli aminoacyl-tRNA synthetases

1 reference

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21 January 2018

Regiospecificity of the hydrolysis of diadenosine polyphosphates catalyzed by three specific pyrophosphohydrolases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Secondary structure of the MutT enzyme as determined by NMR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Sporulation of the yeast Saccharomyces cerevisiae is accompanied by synthesis of adenosine 5'-tetraphosphate and adenosine 5'-pentaphosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Adenosine 5'-tetraphosphate and adenosine 5'-pentaphosphate are synthesized by yeast acetyl coenzyme A synthetase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Synthesis and resistance to enzymic hydrolysis of stereochemically-defined phosphonate and thiophosphate analogues of P1,P4-bis(5'-adenosyl) tetraphosphate

1 reference

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21 January 2018

The green alga Scenedesmus obliquus contains both diadenosine 5',5'''-P1,P4-tetraphosphate (asymmetrical) pyrophosphohydrolase and phosphorylase activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Orf186 Represents a New Member of the Nudix Hydrolases, Active on Adenosine(5′)triphospho(5′)adenosine, ADP-ribose, and NADH

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Characterisation of a bis(5'-nucleosidyl) triphosphate pyrophosphohydrolase from encysted embryos of the brine shrimp Artemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Determination of total protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

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Fluoride is a strong and specific inhibitor of (asymmetrical) Ap4A hydrolases

1 reference

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21 January 2018

Recognition of beta beta'-substituted and alpha beta,alpha'beta'-disubstituted phosphonate analogues of bis(5'-adenosyl) tetraphosphate by the bis(5'-nucleosidyl)-tetraphosphate pyrophosphohydrolases from Artemia embryos and Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Identification of point of specific enzymic cleavage of P1,P4-bis(5'-adenosyl) tetraphosphate by negative ion FAB mass spectrometry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Zinc(II)-dependent synthesis of diadenosine 5', 5"' -P(1) ,P(4) -tetraphosphate by Escherichia coli and yeast phenylalanyl transfer ribonucleic acid synthetases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

Mechanism of synthesis of adenosine(5')tetraphospho(5')adenosine (AppppA) by aminoacyl-tRNA synthetases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8604

21 January 2018

A search in the genome of Saccharomyces cerevisiae for genes regulated via stress response elements

1 reference

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21 January 2018

Identifiers

10.1074/JBC.274.13.8604

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PubMed publication ID

1 reference

PubMed publication ID

1 December 2016

ResearchGate publication ID

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