Tom40 forms the hydrophilic channel of the mitochondrial import pore for preproteins [see comment]. (Q27934927)

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M T Ryan

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K Dietmeier

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F Martin

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R Wagner

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N Pfanner

Common principles of protein translocation across membranes

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language of work or name

English

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publication date

1 October 1998

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1 December 2016

395

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issue

6701

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page(s)

516-21

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cites work

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Protein import into mitochondria

21 January 2018

1 reference

Mitochondrial preprotein translocase

21 January 2018

1 reference

Tim23, a protein import component of the mitochondrial inner membrane, is required for normal activity of the multiple conductance channel, MCC.

21 January 2018

1 reference

Identification of a new pore in the mitochondrial outer membrane of a porin-deficient yeast mutant

21 January 2018

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Detection of likely transmembrane beta strand regions in sequences of mitochondrial pore proteins using the Gibbs sampler

21 January 2018

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Expression of porin from Rhodopseudomonas blastica in Escherichia coli inclusion bodies and folding into exact native structure.

21 January 2018

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Reconstitution of a chloroplast protein import channel

21 January 2018

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A novel method for structure-based prediction of ion channel conductance properties.

21 January 2018

1 reference

Tom5 functionally links mitochondrial preprotein receptors to the general import pore.

21 January 2018

1 reference

The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44.

21 January 2018

1 reference

Artificial mitochondrial presequences

21 January 2018

1 reference

Differential recognition of preproteins by the purified cytosolic domains of the mitochondrial import receptors Tom20, Tom22, and Tom70.

21 January 2018

1 reference

The preprotein translocation channel of the outer membrane of mitochondria.

21 January 2018

1 reference

Protein translocation: tunnel vision

21 January 2018

1 reference

A 42K outer-membrane protein is a component of the yeast mitochondrial protein import site

21 January 2018

1 reference

The mitochondrial receptor complex: Mom22 is essential for cell viability and directly interacts with preproteins

21 January 2018

1 reference

A yeast mitochondrial outer membrane protein essential for protein import and cell viability

21 January 2018

1 reference

DNA-protein conjugates can enter mitochondria via the protein import pathway.

21 January 2018

1 reference

Identification of a mitochondrial receptor complex required for recognition and membrane insertion of precursor proteins

21 January 2018

2 references

21 January 2018

7 January 2021

Mapping of the protein import machinery in the mitochondrial outer membrane by crosslinking of translocation intermediates

1 reference

Relationship between the peptide-sensitive channel and the mitochondrial outer membrane protein translocation machinery

21 January 2018

1 reference

7 January 2021

Mitochondrial protein import. Tom40 plays a major role in targeting and translocation of preproteins by forming a specific binding site for the presequence

1 reference

7 January 2021

Mitochondrial protein import: reversible binding of the presequence at the trans side of the outer membrane drives partial translocation and unfolding

1 reference

7 January 2021