The phosphatase Ppt1 is a dedicated regulator of the molecular chaperone Hsp90 (Q27936139)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407978%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

The phosphatase Ppt1 is a dedicated regulator of the molecular chaperone Hsp90 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407978%20AND%20SRC:MED&resulttype=core&format=json

Protein serine/threonine phosphatase YGR123C

15 January 2020

main subject

molecular chaperones

0 references

1 reference

Hsp90 family chaperone HSP82 YPL240C

GOA release 2020-03-11

1 reference

Hsp90 cochaperone STI1 YOR027W

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Michael H Suhre

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407978%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Sebastian K Wandinger

1

1 reference

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15 January 2020

Harald Wegele

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407978%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Johannes Buchner

4

1 reference

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15 January 2020

language of work or name

English

0 references

publication date

12 January 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407978%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407978%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

25

1 reference

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15 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407978%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

367-376

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Substrate binding to the molecular chaperone Hsp104 and its regulation by nucleotides

15 January 2020

cites work

1 reference

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Cns1 is an activator of the Ssa1 ATPase activity

20 March 2017

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Characterization of Saccharomyces cerevisiae protein Ser/Thr phosphatase T1 and comparison to its mammalian homolog PP5

20 March 2017

1 reference

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Sti1 is a non-competitive inhibitor of the Hsp90 ATPase. Binding prevents the N-terminal dimerization reaction during the atpase cycle

20 March 2017

1 reference

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Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1

20 March 2017

1 reference

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Functional organization of the yeast proteome by systematic analysis of protein complexes

20 March 2017

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Hsp90: a specialized but essential protein-folding tool

20 March 2017

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Cpr6 and Cpr7, two closely related Hsp90-associated immunophilins from Saccharomyces cerevisiae, differ in their functional properties

20 March 2017

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Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine

20 March 2017

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Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones

20 March 2017

1 reference

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In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

20 March 2017

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The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions

20 March 2017

1 reference

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Phosphorylation of the immunosuppressant FK506-binding protein FKBP52 by casein kinase II: regulation of HSP90-binding activity of FKBP52

20 March 2017

1 reference

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In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone

20 March 2017

1 reference

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Cdc37 is a molecular chaperone with specific functions in signal transduction

20 March 2017

1 reference

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Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes

20 March 2017

1 reference

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A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus

20 March 2017

1 reference

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Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase

20 March 2017

1 reference

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Calcineurin functions in Ca(2+)-activated cell death in mammalian cells

20 March 2017

1 reference

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Transformation of intact yeast cells treated with alkali cations

20 March 2017

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 March 2017

1 reference

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STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Molecular cloning and expression of a transformation-sensitive human protein containing the TPR motif and sharing identity to the stress-inducible yeast protein STI1

20 March 2017

1 reference

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Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

The tetratricopeptide repeat domain of protein phosphatase 5 mediates binding to glucocorticoid receptor heterocomplexes and acts as a dominant negative mutant

20 March 2017

1 reference

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Molecular cloning of a protein serine/threonine phosphatase containing a putative regulatory tetratricopeptide repeat domain

20 March 2017

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

20 March 2017

1 reference

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HSP90 and the chaperoning of cancer

7 April 2017

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Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

7 April 2017

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Molecular basis for TPR domain-mediated regulation of protein phosphatase 5.

7 April 2017

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Hsp42 is the general small heat shock protein in the cytosol of Saccharomyces cerevisiae

29 September 2017

1 reference

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Hsp70 and Hsp90--a relay team for protein folding

29 September 2017

1 reference

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Structure and functional relationships of Hsp90.

29 September 2017

1 reference

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Phosphorylation of serine 13 is required for the proper function of the Hsp90 co-chaperone, Cdc37.

29 September 2017

1 reference

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Heat-shock protein 90, a chaperone for folding and regulation

29 September 2017

1 reference

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Phosphorylation and oligomerization states of native pig brain HSP90 studied by mass spectrometry

29 September 2017

1 reference

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Protein phosphatase 5 in signal transduction.

29 September 2017

1 reference

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29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Identification of conserved residues required for the binding of a tetratricopeptide repeat domain to heat shock protein 90.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

The common tetratricopeptide repeat acceptor site for steroid receptor-associated immunophilins and hop is located in the dimerization domain of Hsp90.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Hsp90 is required for pheromone signaling in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Purification of a fatty acid-stimulated protein-serine/threonine phosphatase from bovine brain and its identification as a homolog of protein phosphatase 5.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Novel protein serine/threonine phosphatases: variety is the spice of life

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Mutational analysis of the catalytic subunit of muscle protein phosphatase-1.

29 September 2017

1 reference

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Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Targeting of a distinctive protein-serine phosphatase to the protein kinase-like domain of the atrial natriuretic peptide receptor

29 September 2017

1 reference

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Heat-shock protein hsp90 governs the activity of pp60v-src kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

The ability of the immunophilin FKBP59-HBI to interact with the 90-kDa heat shock protein is encoded by its tetratricopeptide repeat domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Possible role for serine/threonine phosphorylation in the regulation of the heteroprotein complex between the hsp90 stress protein and the pp60v-src tyrosine kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Proteins that glow in green and blue

29 September 2017

1 reference

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Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

Stress-inducible, murine protein mSTI1. Characterization of binding domains for heat shock proteins and in vitro phosphorylation by different kinases

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383513

The specific interaction of the Rous sarcoma virus transforming protein, pp60src, with two cellular proteins

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600930

Identification of amino acids in the tetratricopeptide repeat and C-terminal domains of protein phosphatase 5 involved in autoinhibition and lipid activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600930

The in vitro phosphorylation of the co-chaperone mSTI1 by cell cycle kinases substantiates a predicted casein kinase II-p34cdc2-NLS (CcN) motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600930

Identification of potential physiological activators of protein phosphatase 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600930

Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600930

Structural basis for the catalytic activity of human serine/threonine protein phosphatase-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600930

Recombinant expression and purification of Ssa1p (Hsp70) from Saccharomyces cerevisiae using Pichia pastoris.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600930

A model of protein targeting mediated by immunophilins and other proteins that bind to hsp90 via tetratricopeptide repeat domains

21 January 2018

1 reference

12 December 2020

Purification and characterization of prokaryotic and eukaryotic Hsp90

1 reference

12 December 2020

The mode of action of peptidyl prolyl cis/trans isomerases in vivo: binding vs. catalysis

1 reference

12 December 2020

Dynamics of heat shock protein 90-progesterone receptor binding and the disactivation loop model for steroid receptor complexes

1 reference

12 December 2020

Mutational analysis of a Ser/Thr phosphatase. Identification of residues important in phosphoesterase substrate binding and catalysis

1 reference

12 December 2020

The tetratricopeptide repeat domain and a C-terminal region control the activity of Ser/Thr protein phosphatase 5

1 reference

12 December 2020

The molecular chaperone Cdc37 is required for Ste11 function and pheromone-induced cell cycle arrest

1 reference

12 December 2020

Overlapping sites of tetratricopeptide repeat protein binding and chaperone activity in heat shock protein 90

1 reference

12 December 2020

Chaperone function of Hsp90-associated proteins

1 reference

12 December 2020

Molecular chaperone machines: chaperone activities of the cyclophilin Cyp-40 and the steroid aporeceptor-associated protein p23

1 reference

12 December 2020

Activation of protein phosphatase 5 by limited proteolysis or the binding of polyunsaturated fatty acids to the TPR domain

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600930

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407978%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

15 January 2020

1158146

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407978%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

16407978

1 reference