Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function (Q27936467)

Actin-related protein 3 YJR065C

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Yidi Sun

5

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Marko Kaksonen

Marko Kaksonen

4

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Isabelle Rouiller

Isabelle Rouiller

3

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David G Drubin

10

David G Drubin

0 references

Dorit Hanein

8

Dorit Hanein

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author name string

Adam C Martin

1

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Xiao-Ping Xu

2

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Lisa Belmont

6

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Niels Volkmann

7

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Matthew Welch

ARPC1/Arc40 mediates the interaction of the actin-related protein 2 and 3 complex with Wiskott-Aldrich syndrome protein family activators

9

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language of work or name

English

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publication date

17 January 2005

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published in

Journal of Cell Biology

1 reference

1 December 2016

168

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page(s)

315-28

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issue

2

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Activation of Arp2/3 complex: addition of the first subunit of the new filament by a WASP protein triggers rapid ATP hydrolysis on Arp2

20 March 2017

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A pathway for association of receptors, adaptors, and actin during endocytic internalization.

20 March 2017

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The structure of nonvertebrate actin: Implications for the ATP hydrolytic mechanism

20 March 2017

1 reference

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Crystal structure of Arp2/3 complex

20 March 2017

1 reference

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In vivo importance of actin nucleotide exchange catalyzed by profilin

20 March 2017

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EMAN: semiautomated software for high-resolution single-particle reconstructions

20 March 2017

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The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex.

20 March 2017

1 reference

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Genetic dissection of the budding yeast Arp2/3 complex: a comparison of the in vivo and structural roles of individual subunits

20 March 2017

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Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia

20 March 2017

1 reference

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The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches.

20 March 2017

1 reference

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Atomic structure of the actin:DNase I complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Structure of Arp2/3 complex in its activated state and in actin filament branch junctions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization

20 March 2017

1 reference

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Arp2/3 complex requires hydrolyzable ATP for nucleation of new actin filaments

20 March 2017

1 reference

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Actin Assembly and Endocytosis: From Yeast to Mammals

20 March 2017

1 reference

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Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Negative regulation of yeast WASp by two SH3 domain-containing proteins

7 April 2017

1 reference

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Critical conformational changes in the Arp2/3 complex are induced by nucleotide and nucleation promoting factor.

9 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Yeast actin patches are networks of branched actin filaments.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

ATP hydrolysis on actin-related protein 2/3 complex causes debranching of dendritic actin arrays

29 September 2017

1 reference

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29 September 2017

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How does ATP hydrolysis control actin's associations?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Cellular control of actin nucleation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

The Arp2/3 complex nucleates actin filament branches from the sides of pre-existing filaments

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

A change in actin conformation associated with filament instability after Pi release.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

The yeast V159N actin mutant reveals roles for actin dynamics in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

The yeast actin-related protein Arp2p is required for the internalization step of endocytosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Identification of two regions in the N-terminal domain of ActA involved in the actin comet tail formation by Listeria monocytogenes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

The Saccharomyces cerevisiae actin-related protein Arp2 is involved in the actin cytoskeleton

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Systematic mutational analysis of the yeast ACT1 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Neural Wiskott Aldrich Syndrome Protein (N-WASP) and the Arp2/3 complex are recruited to sites of clathrin-mediated endocytosis in cultured fibroblasts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Three regions within ActA promote Arp2/3 complex-mediated actin nucleation and Listeria monocytogenes motility

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

New actin mutants allow further characterization of the nucleotide binding cleft and drug binding sites

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171590

Activation of Arp2/3 complex by Wiskott-Aldrich Syndrome protein is linked to enhanced binding of ATP to Arp2.

2 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200408177

A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200408177

Quantitative fitting of atomic models into observed densities derived by electron microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200408177

Docking of atomic models into reconstructions from electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200408177

The dynamics of actin-based motility depend on surface parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200408177

Dynamics of yeast Myosin I: evidence for a possible role in scission of endocytic vesicles

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15657399

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The effect of the S14A mutation on the conformation and thermostability of Saccharomyces cerevisiae G-actin and its interaction with adenine nucleotides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15657399

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15657399

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.200408177

1 reference

4538579

4538579

1 reference

1 reference

1 reference