Targeting an mRNA for decapping: displacement of translation factors and association of the Lsm1p-7p complex on deadenylated yeast mRNAs (Q27936762)

PubMed

PubMed publication ID

11741542

1 December 2016

title

Targeting an mRNA for decapping: displacement of translation factors and association of the Lsm1p-7p complex on deadenylated yeast mRNAs (English)

1 reference

PubMed

PubMed publication ID

1 December 2016

1 reference

GOA release 2020-03-11

author name string

S Tharun

series ordinal

1

0 references

R Parker

series ordinal

2

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language of work or name

English

0 references

publication date

November 2001

0 references

1 reference

PubMed publication ID

11741542

An essential component of the decapping enzyme required for normal rates of mRNA turnover

1 December 2016

volume

8

0 references

issue

5

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page(s)

1075-83

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cites work

1 reference

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7 January 2021

Capped mRNA degradation intermediates accumulate in the yeast spb8-2 mutant

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The two proteins Pat1p (Mrt1p) and Spb8p interact in vivo, are required for mRNA decay, and are functionally linked to Pab1p

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A Sm-like protein complex that participates in mRNA degradation

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7 January 2021

Multiple functions for the poly(A)-binding protein in mRNA decapping and deadenylation in yeast

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A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation

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7 January 2021

The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif

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7 January 2021

Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins

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Mutations in trans-acting factors affecting mRNA decapping in Saccharomyces cerevisiae

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Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure

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Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells

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Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

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7 January 2021

The Y14 protein communicates to the cytoplasm the position of exon-exon junctions

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The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

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Characterization of Sm-like proteins in yeast and their association with U6 snRNA

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Mutations affecting stability and deadenylation of the yeast MFA2 transcript

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Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript

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Turnover mechanisms of the stable yeast PGK1 mRNA

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Starting at the beginning, middle, and end: translation initiation in eukaryotes

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Mutations in translation initiation factors lead to increased rates of deadenylation and decapping of mRNAs in Saccharomyces cerevisiae

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mRNA decapping in yeast requires dissociation of the cap binding protein, eukaryotic translation initiation factor 4E.

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Yeast Sm-like proteins function in mRNA decapping and decay

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Mechanisms and control of mRNA decapping in Saccharomyces cerevisiae

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The eukaryotic mRNA decapping protein Dcp1 interacts physically and functionally with the eIF4F translation initiation complex

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7 January 2021

Deletion of the PAT1 gene affects translation initiation and suppresses a PAB1 gene deletion in yeast

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The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans

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