Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε. (Q27937434)

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17 January 2020

title

Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε (English)

1 reference

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DNA polymerase epsilon catalytic subunit YNL262W

17 January 2020

main subject

1 reference

DNA polymerase epsilon noncatalytic subunit YBR278W

GOA release 2020-03-11

1 reference

DNA polymerase epsilon noncatalytic subunit YDR121W

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

4

1 reference

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17 January 2020

Igor B. Rogozin

5

1 reference

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17 January 2020

Thomas A Kunkel

6

1 reference

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17 January 2020

author name string

Anna Aksenova

1

1 reference

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17 January 2020

Kirill Volkov

2

1 reference

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17 January 2020

Jaroslaw Maceluch

3

1 reference

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17 January 2020

Youri I Pavlov

7

1 reference

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17 January 2020

Erik Johansson

8

1 reference

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17 January 2020

language of work or name

English

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publication date

18 November 2010

1 reference

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17 January 2020

2 references

1 December 2016

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17 January 2020

volume

6

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17 January 2020

issue

11

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17 January 2020

page(s)

e1001209

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Creative Commons CC0 License

17 January 2020

copyright license

start time

18 November 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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describes a project that uses

ImageQuant

object named as

ImageQuant

2 references

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2987839/fullTextXML

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

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Conformational changes associated with template commitment in ATP-dependent chromatin remodeling by ISW2

20 March 2017

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Defective interaction between Pol2p and Dpb2p, subunits of DNA polymerase epsilon, contributes to a mutator phenotype in Saccharomyces cerevisiae

20 March 2017

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Polymerase dynamics at the eukaryotic DNA replication fork

20 March 2017

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Dpb2p, a noncatalytic subunit of DNA polymerase epsilon, contributes to the fidelity of DNA replication in Saccharomyces cerevisiae

20 March 2017

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Yeast DNA polymerase epsilon participates in leading-strand DNA replication

20 March 2017

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The Dpb4 subunit of ISW2 is anchored to extranucleosomal DNA.

20 March 2017

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Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy.

20 March 2017

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Proteomic and genomic characterization of chromatin complexes at a boundary

20 March 2017

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The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains

20 March 2017

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Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication

20 March 2017

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Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations

20 March 2017

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Cell cycle-dependent phosphorylation of the DNA polymerase epsilon subunit, Dpb2, by the Cdc28 cyclin-dependent protein kinase

20 March 2017

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Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae

20 March 2017

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Double‐stranded DNA binding properties of Saccharomyces cerevisiae DNA polymerase ɛ and of the Dpb3p‐Dpb4p subassembly

20 March 2017

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Unique error signature of the four-subunit yeast DNA polymerase epsilon

20 March 2017

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The quaternary structure of DNA polymerase epsilon from Saccharomyces cerevisiae

20 March 2017

1 reference

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Pol32, a subunit of Saccharomyces cerevisiae DNA polymerase delta, suppresses genomic deletions and is involved in the mutagenic bypass pathway

20 March 2017

1 reference

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The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

20 March 2017

1 reference

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Cloning DPB3, the gene encoding the third subunit of DNA polymerase II of Saccharomyces cerevisiae

20 March 2017

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Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity

20 March 2017

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Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae

20 March 2017

1 reference

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Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick

20 March 2017

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DNA polymerases at the eukaryotic fork-20 years later

20 March 2017

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Division of labor at the eukaryotic replication fork

20 March 2017

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20 March 2017

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Functions of DNA polymerases

20 March 2017

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In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zeta

20 March 2017

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Ubiquitin-dependent DNA damage bypass is separable from genome replication

20 March 2017

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Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae

29 September 2017

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DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice

29 September 2017

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The mismatch repair system promotes DNA polymerase zeta-dependent translesion synthesis in yeast.

29 September 2017

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Mechanisms of dealing with DNA damage-induced replication problems

29 September 2017

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Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.

29 September 2017

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Dividing the workload at a eukaryotic replication fork

29 September 2017

1 reference

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Mismatch repair-dependent processing of methylation damage gives rise to persistent single-stranded gaps in newly replicated DNA.

29 September 2017

1 reference

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The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA.

29 September 2017

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DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse

29 September 2017

1 reference

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The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins.

29 September 2017

1 reference

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A novel function of DNA polymerase zeta regulated by PCNA.

29 September 2017

1 reference

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DNA polymerases that propagate the eukaryotic DNA replication fork

29 September 2017

1 reference

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Cellular functions of DNA polymerase zeta and Rev1 protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

Genomic Instability Induced by Mutations in Saccharomyces cerevisiae POL1

29 September 2017

1 reference

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Schizosacchromyces pombe Dpb2 binds to origin DNA early in S phase and is required for chromosomal DNA replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

Evidence for Preferential Mismatch Repair of Lagging Strand DNA Replication Errors in Yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

DNA mismatch repair and genetic instability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase delta or by decreases in the cellular levels of DNA polymerase delta

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

A DNA polymerase epsilon mutant that specifically causes +1 frameshift mutations within homonucleotide runs in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

Characterization of the repeat-tract instability and mutator phenotypes conferred by a Tn3 insertion in RFC1, the large subunit of the yeast clamp loader

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

The prevention of repeat-associated deletions in Saccharomyces cerevisiae by mismatch repair depends on size and origin of deletions.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

The RAD6 DNA damage tolerance pathway operates uncoupled from the replication fork and is functional beyond S phase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

3'-->5' exonucleases of DNA polymerases epsilon and delta correct base analog induced DNA replication errors on opposite DNA strands in Saccharomyces cerevisiae

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

Analyzing fidelity of DNA polymerases.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

Statistical test for the comparison of samples from mutational spectra

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2987839

Evidence from mutational specificity studies that yeast DNA polymerases delta and epsilon replicate different DNA strands at an intracellular replication fork

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001209

The replisome uses mRNA as a primer after colliding with RNA polymerase

21 January 2018

1 reference

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Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001209

The efficiency and specificity of apurinic/apyrimidinic site bypass by human DNA polymerase eta and Sulfolobus solfataricus Dpo4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001209

Multiple Mechanisms Control Chromosome Integrity after Replication Fork Uncoupling and Restart at Irreparable UV Lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001209

21 January 2018

1 reference

12 December 2020

Base analog 6-N-hydroxylaminopurine mutagenesis in the yeast Saccharomyces cerevisiae is controlled by replicative DNA polymerases

1 reference

12 December 2020

Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon

1 reference

12 December 2020

The 3'-->5' exonucleases of both DNA polymerases delta and epsilon participate in correcting errors of DNA replication in Saccharomyces cerevisiae

1 reference

12 December 2020

Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1001209

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21124948%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

2 references

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17 January 2020

2 references