Differential requirements of novel A1PiZ degradation deficient (ADD)genes in ER-associated protein degradation (Q27938609)

27 December 2023

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GOA release 2020-03-11

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27 December 2023

2

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Ardythe A. McCracken

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author name string

Elizabeth A. Palmer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12711700

27 December 2023

Sheara W. Fewell

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12711700

27 December 2023

Sean M. Buchanan

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12711700

27 December 2023

Jeffrey L. Brodsky

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12711700

27 December 2023

language of work or name

English

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publication date

1 June 2003

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23 April 2003

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12711700

full work available at URL

27 December 2023

http://journals.biologists.com/jcs/article-pdf/116/11/2361/1487119/2361.pdf

file format

Portable Document Format

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Basic local alignment search tool

27 December 2023

published in

Journal of Cell Science

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1 December 2016

116

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issue

Pt 11

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page(s)

2361-73

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cites work

2

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Plasma membrane proton ATPase Pma1p requires raft association for surface delivery in yeast

27 December 2023

3

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Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

27 December 2023

4

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Cdc48-Ufd1-Npl4: stuck in the middle with Ub.

27 December 2023

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Role of Erv29p in collecting soluble secretory proteins into ER-derived transport vesicles

27 December 2023

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Glycoprotein folding in the endoplasmic reticulum

27 December 2023

7

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Role of Cue1p in ubiquitination and degradation at the ER surface

27 December 2023

8

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Mutations in the cytosolic DnaJ homologue, YDJ1, delay and compromise the efficient translation of heterologous proteins in yeast

27 December 2023

9

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ER protein quality control and proteasome-mediated protein degradation

27 December 2023

10

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The requirement for molecular chaperones during endoplasmic reticulum-associated protein degradation demonstrates that protein export and import are mechanistically distinct

27 December 2023

11

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Processing by endoplasmic reticulum mannosidases partitions a secretion-impaired glycoprotein into distinct disposal pathways

27 December 2023

12

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Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and Golgi

27 December 2023

13

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Inositol lipids as spatial regulators of membrane traffic

27 December 2023

15

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Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

27 December 2023

16

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Membrane topology and function of Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation

27 December 2023

17

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ER quality control: towards an understanding at the molecular level

27 December 2023

18

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Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast

27 December 2023

19

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The action of molecular chaperones in the early secretory pathway

27 December 2023

20

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CAFASP-1: Critical assessment of fully automated structure prediction methods

27 December 2023

21

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A regulatory link between ER-associated protein degradation and the unfolded-protein response

27 December 2023

22

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Functional organization of the yeast proteome by systematic analysis of protein complexes

27 December 2023

23

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Export of a cysteine-free misfolded secretory protein from the endoplasmic reticulum for degradation requires interaction with protein disulfide isomerase

27 December 2023

25

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The protein translocation channel mediates glycopeptide export across the endoplasmic reticulum membrane

27 December 2023

26

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Apoprotein B degradation is promoted by the molecular chaperones hsp90 and hsp70.

27 December 2023

27

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Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

27 December 2023

28

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Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase

27 December 2023

29

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ER stress response: getting the UPR hand on misfolded proteins

27 December 2023

30

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An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport

27 December 2023

31

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Regulation of protein biogenesis at the endoplasmic reticulum membrane

27 December 2023

32

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Degradation of unassembled Vph1p reveals novel aspects of the yeast ER quality control system

27 December 2023

33

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ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

27 December 2023

34

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Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

27 December 2023

35

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A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli

27 December 2023

36

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Characterization of a novel ADP-ribosylation factor-like protein (yARL3) in Saccharomyces cerevisiae

27 December 2023

37

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Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome

27 December 2023

38

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A comprehensive two-hybrid analysis to explore the yeast protein interactome

27 December 2023

39

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Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

27 December 2023

40

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Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.

27 December 2023

41

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Resistance to cadmium mediated by ubiquitin-dependent proteolysis.

27 December 2023

42

1 reference

Tor-mediated induction of autophagy via an Apg1 protein kinase complex

27 December 2023

44

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Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes

27 December 2023

45

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Applications and statistics for multiple high-scoring segments in molecular sequences

27 December 2023

46

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Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

27 December 2023

47

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GI Domain-mediated Association of the Eukaryotic Initiation Factor 2α Kinase GCN2 with Its Activator GCN1 Is Required for General Amino Acid Control in Budding Yeast

27 December 2023

51

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New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism

27 December 2023

52

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Ubiquitin-mediated proteolysis of a short-lived regulatory protein depends on its cellular localization

27 December 2023

53

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Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth

27 December 2023

55

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The mechanism of Z alpha 1-antitrypsin accumulation in the liver

27 December 2023

56

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The mitochondrial proteins Ssq1 and Jac1 are required for the assembly of iron sulfur clusters in mitochondria

27 December 2023

57

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Glucosidase and mannosidase inhibitors mediate increased secretion of mutant alpha1 antitrypsin Z.

27 December 2023

59

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Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP.

27 December 2023

60

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Selective protein degradation in the yeast exocytic pathway

27 December 2023

61

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Gos1p, a Saccharomyces cerevisiae SNARE protein involved in Golgi transport.

27 December 2023

63

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A cytoskeleton-related gene, uso1, is required for intracellular protein transport in Saccharomyces cerevisiae

27 December 2023

66

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The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control

27 December 2023

68

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Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

27 December 2023

69

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Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

27 December 2023

70

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Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

27 December 2023

71

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Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

27 December 2023

73

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Retrograde protein translocation: ERADication of secretory proteins in health and disease

27 December 2023

75

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Cell-free translation of the mRNAs for the heavy and light chains of HLA-A and HLA-B antigens

27 December 2023

76

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Degradation of a mutant secretory protein, alpha1-antitrypsin Z, in the endoplasmic reticulum requires proteasome activity

27 December 2023

77

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AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

27 December 2023

78

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Large-scale analysis of the yeast genome by transposon tagging and gene disruption

27 December 2023

80

1 reference

Sec31 encodes an essential component of the COPII coat required for transport vesicle budding from the endoplasmic reticulum

27 December 2023

81

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Coat proteins and vesicle budding

27 December 2023

82

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The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate

27 December 2023

83

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Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol

27 December 2023

84

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BiP/Kar2p serves as a molecular chaperone during carboxypeptidase Y folding in yeast

27 December 2023

85

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The endoplasmic reticulum degradation pathway for mutant secretory proteins alpha1-antitrypsin Z and S is distinct from that for an unassembled membrane protein

27 December 2023

87

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

27 December 2023

90

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Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

27 December 2023

91

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Sensitivity of mammalian cells expressing mutant ubiquitin to protein-damaging agents

27 December 2023

92

1 reference

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

27 December 2023

93

1 reference

Dislocation and degradation from the ER are regulated by cytosolic stress

27 December 2023

94

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Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding

27 December 2023

95

1 reference

Jac1, a mitochondrial J-type chaperone, is involved in the biogenesis of Fe/S clusters in Saccharomyces cerevisiae

27 December 2023

96

1 reference

New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae

27 December 2023

97

1 reference

Eps1, a novel PDI-related protein involved in ER quality control in yeast

27 December 2023

98

1 reference

Degradation of CFTR by the ubiquitin-proteasome pathway

27 December 2023

99

1 reference

Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate

27 December 2023

100

1 reference

HRD gene dependence of endoplasmic reticulum-associated degradation

27 December 2023

101

1 reference

Pivotal role of calnexin and mannose trimming in regulating the endoplasmic reticulum-associated degradation of major histocompatibility complex class I heavy chain.

27 December 2023

102

1 reference

Degradation of distinct assembly forms of immunoglobulin M occurs in multiple sites in permeabilized B cells

27 December 2023

103

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The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment

27 December 2023

105

1 reference

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

27 December 2023

106

1 reference

The Z type variation of human alpha 1-antitrypsin causes a protein folding defect

27 December 2023

107

1 reference

Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast

27 December 2023

108

1 reference