Recruitment of PfSET2 by RNA polymerase II to variant antigen encoding loci contributes to antigenic variation in P. falciparum (Q27976479)

histone-lysine N-methyltransferase SET2

10 September 2018

1 reference

11 September 2018

1 reference

25 September 2018

1 reference

15 December 2018

1 reference

19 December 2018

1 reference

20 December 2018

1 reference

21 December 2018

Chethan Pandarinath

4

0 references

author name string

Uchechi E Ukaegbu

1

0 references

Sandeep P Kishore

2

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Dacia L Kwiatkowski

3

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Noa Dahan-Pasternak

5

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Ron Dzikowski

6

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Kirk W Deitsch

Creative Commons Attribution 4.0 International

7

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language of work or name

English

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publication date

January 2014

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published in

PLOS Pathogens

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volume

10

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issue

1

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page(s)

e1003854

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copyright license

start time

2 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytes

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Insulator-like pairing elements regulate silencing and mutually exclusive expression in the malaria parasite Plasmodium falciparum

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Var Gene promoter activation in clonal Plasmodium falciparum isolates follows a hierarchy and suggests a conserved switching program that is independent of genetic background

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29 September 2017

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Functional analysis of epigenetic regulation of tandem RhopH1/clag genes reveals a role in Plasmodium falciparum growth

29 September 2017

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Plasmodium falciparum var gene silencing is determined by cis DNA elements that form stable and heritable interactions

29 September 2017

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29 September 2017

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29 September 2017

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An unusual recent expansion of the C-terminal domain of RNA polymerase II in primate malaria parasites features a motif otherwise found only in mammalian polymerases.

29 September 2017

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29 September 2017

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29 September 2017

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Chromatin associated sense and antisense noncoding RNAs are transcribed from the var gene family of virulence genes of the malaria parasite Plasmodium falciparum

29 September 2017

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Crosstalk among Histone Modifications

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Active transcription is required for maintenance of epigenetic memory in the malaria parasite Plasmodium falciparum

29 September 2017

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A regulatable transgene expression system for cultured Plasmodium falciparum parasites

29 September 2017

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Molecular evolution of the RNA polymerase II CTD.

29 September 2017

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Default Pathway of var2csa switching and translational repression in Plasmodium falciparum

29 September 2017

1 reference

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Histone lysine methyltransferases and demethylases in Plasmodium falciparum

29 September 2017

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Shared epigenetic mechanisms control virulence factors in protozoan parasites

29 September 2017

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Mechanisms underlying mutually exclusive expression of virulence genes by malaria parasites

29 September 2017

1 reference

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Epigenetic silencing of Plasmodium falciparum genes linked to erythrocyte invasion

29 September 2017

1 reference

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Variable switching rates of malaria virulence genes are associated with chromosomal position

29 September 2017

1 reference

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Epigenetic memory at malaria virulence genes

29 September 2017

1 reference

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Variant antigen gene expression in malaria

29 September 2017

1 reference

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Strict pairing of var promoters and introns is required for var gene silencing in the malaria parasite Plasmodium falciparum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879369

Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase

29 September 2017

1 reference

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A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation

29 September 2017

1 reference

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A silenced Plasmodium falciparum var promoter can be activated in vivo through spontaneous deletion of a silencing element in the intron

29 September 2017

1 reference

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Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria

29 September 2017

1 reference

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A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern.

29 September 2017

1 reference

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Tails of intrigue: phosphorylation of RNA polymerase II mediates histone methylation

29 September 2017

1 reference

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Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast

29 September 2017

1 reference

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The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879369

Two long non-coding RNAs generated from subtelomeric regions accumulate in a novel perinuclear compartment in Plasmodium falciparum.

29 September 2017

1 reference

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Heterochromatin formation in bistable chromatin domains controls the epigenetic repression of clonally variant Plasmodium falciparum genes linked to erythrocyte invasion.

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003854

Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003854

Histone H3 lysine 36 dimethylation (H3K36me2) is sufficient to recruit the Rpd3s histone deacetylase complex and to repress spurious transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003854

Differential sub-nuclear localisation of repressive and activating histone methyl modifications in P. falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003854

Global histone analysis by mass spectrometry reveals a high content of acetylated lysine residues in the malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003854

Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003854

Plasmodium falciparum var genes are regulated by two regions with separate promoters, one upstream of the coding region and a second within the intron.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003854

Extraction, purification and analysis of histones

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24391504

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phosphorylation of the RNA polymerase II C-terminal domain dictates transcription termination choice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24391504

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PPAT.1003854

1 reference

3644466

3644466

1 reference

1 reference

1 reference