Obesity and stroke: Can we translate from rodents to patients? (Q28066560)

language of work or name

1 reference

December 2016

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Journal of Cerebral Blood Flow & Metabolism

1 December 2016

10 references

19 March 2019

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25 April 2019

17 June 2019

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20 August 2019

24 June 2020

30 September 2020

11 references

19 March 2019

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36

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issue

12

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page(s)

2007-2021

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Creative Commons Attribution 3.0 Unported

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Critical role of matrix metalloprotease-9 in chronic high fat diet-induced cerebral vascular remodelling and increase of ischaemic brain injury in mice†.

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29 September 2017

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Increased cerebral matrix metalloprotease-9 activity is associated with compromised recovery in the diabetic db/db mouse following a stroke

29 September 2017

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Enhanced endothelin-1 system activity with overweight and obesity

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Systemic effects of white adipose tissue dysregulation and obesity-related inflammation

29 September 2017

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The role of adipose tissue and adipokines in obesity-related inflammatory diseases

29 September 2017

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29 September 2017

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Association of obesity and biomarkers of inflammation and endothelial dysfunction in adults in Inner Mongolia, China

29 September 2017

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Preventing increased blood pressure in the obese Zucker rat improves severity of stroke

29 September 2017

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29 September 2017

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Cognitive impairment following high fat diet consumption is associated with brain inflammation.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Diet-induced obesity causes cerebral vessel remodeling and increases the damage caused by ischemic stroke

29 September 2017

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29 September 2017

1 reference

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Obesity increases blood pressure, cerebral vascular remodeling, and severity of stroke in the Zucker rat.

29 September 2017

1 reference

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Hypertension and cerebrovascular damage

29 September 2017

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Does body weight influence the response to intravenous tissue plasminogen activator in stroke patients?

29 September 2017

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Leptin is induced in the ischemic cerebral cortex and exerts neuroprotection through NF-kappaB/c-Rel-dependent transcription.

29 September 2017

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The effects of body mass index on cerebral blood flow velocity

29 September 2017

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Acute treatment with rosuvastatin protects insulin resistant (C57BL/6J ob/ob) mice against transient cerebral ischemia

29 September 2017

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CD36/fatty acid translocase, an inflammatory mediator, is involved in hyperlipidemia-induced exacerbation in ischemic brain injury

29 September 2017

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Inflammatory and injury responses to ischemic stroke in obese mice

29 September 2017

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Adiponectin prevents cerebral ischemic injury through endothelial nitric oxide synthase dependent mechanisms

29 September 2017

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Increased hemorrhagic transformation and altered infarct size and localization after experimental stroke in a rat model type 2 diabetes

29 September 2017

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Diabetes, the metabolic syndrome, and ischemic stroke: epidemiology and possible mechanisms

29 September 2017

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Plasminogen activator inhibitor-1 contributes to the deleterious effect of obesity on the outcome of thrombotic ischemic stroke in mice

29 September 2017

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Adiponectin does not cross the blood-brain barrier but modifies cytokine expression of brain endothelial cells

29 September 2017

1 reference

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Signalling role of adipose tissue: adipokines and inflammation in obesity

29 September 2017

1 reference

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Adiponectin: protection of the endothelium

29 September 2017

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Prospective study of body mass index and risk of stroke in apparently healthy women.

29 September 2017

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29 September 2017

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Estrogen stimulates microglia and brain recovery from hypoxia-ischemia in normoglycemic but not diabetic female mice

29 September 2017

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Body mass index and the risk of stroke in men.

29 September 2017

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Plasma concentration of C-reactive protein and risk of ischemic stroke and transient ischemic attack: the Framingham study

29 September 2017

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Experimental stroke in the female diabetic, db/db, mouse

29 September 2017

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C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?

29 September 2017

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The obesity paradox in stroke: lower mortality and lower risk of readmission for recurrent stroke in obese stroke patients

29 September 2017

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CD36 in the periphery and brain synergizes in stroke injury in hyperlipidemia

2 June 2018

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Association between obesity and mortality after acute first-ever stroke: the obesity-stroke paradox

2 June 2018

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Experimental stroke-induced changes in the bone marrow reveal complex regulation of leukocyte responses

2 June 2018

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Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia

2 June 2018

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A prospective study of body mass index, weight change, and risk of stroke in women

2 June 2018

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Urgent therapy for stroke. Part I. Pilot study of tissue plasminogen activator administered within 90 minutes

2 June 2018

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2 June 2018

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Body mass index and cardiovascular disease in the Asia-Pacific Region: an overview of 33 cohorts involving 310 000 participants

21 January 2018

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Body mass index and ischemic and hemorrhagic stroke: a prospective study in Korean men.

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Metabolic Syndrome Predicts Refractoriness to Intravenous Thrombolysis in Acute Ischemic Stroke.

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21 January 2018

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https://api.crossref.org/works/10.1177%2F0271678X16670411

Body mass index and poststroke mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Dynamics of obesity paradox after stroke, related to time from onset, age, and causes of death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Overweight and obesity are associated with improved survival, functional outcome, and stroke recurrence after acute stroke or transient ischaemic attack: observations from the TEMPiS trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Obesity paradox versus frailty syndrome in first-ever ischemic stroke survivors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

The obesity paradox and survivors of ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

The impact of body mass index on mortality after stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Is there a decreased risk of intracerebral hemorrhage and mortality in obese patients treated with intravenous thrombolysis in acute ischemic stroke?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Obesity-stroke paradox and initial neurological severity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Obesity paradox and stroke: noticing the (fat) man behind the curtain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

The impact of body weight on mortality after stroke: the controversy continues

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Prolonged diet-induced obesity in mice modifies the inflammatory response and leads to worse outcome after stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Effects of high-fat diet on neuronal damage, gliosis, inflammatory process and oxidative stress in the hippocampus induced by transient cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Exacerbation of ischemic brain injury in hypercholesterolemic mice is associated with pronounced changes in peripheral and cerebral immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

A high fat diet does not exacerbate CA1 injury and cognitive deficits following global ischemia in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Impaired wound healing after cerebral hypoxia-ischemia in the diabetic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Ischemic hippocampal cell death induces glucose dysregulation by attenuating glucose-stimulated insulin secretion which is exacerbated by a high fat diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Early hemorrhagic transformation of brain infarction: rate, predictive factors, and influence on clinical outcome: results of a prospective multicenter study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Obesity exacerbates sepsis-induced inflammation and microvascular dysfunction in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

A rapid and transient peripheral inflammatory response precedes brain inflammation after experimental stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Obesity and the white blood cell count: changes with sustained weight loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Neutrophil activation in morbid obesity, chronic activation of acute inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Functional capacity of neutrophils from class III obese patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Impact of obesity on stroke outcome after intravenous thrombolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Thrombolysis outcomes among obese and overweight stroke patients: an age- and National Institutes of Health Stroke Scale-matched comparison

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

High fat and high fructose diet induced intracranial atherosclerosis and enhanced vasoconstrictor responses in non-human primate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Metabolic syndrome in relation to structure and function of large arteries: a predominant effect of blood pressure. A report from the SU.VI.MAX. Vascular Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

A detailed cardiovascular characterization of obesity without the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Adiponectin protects against cerebral ischemia-reperfusion injury through anti-inflammatory action

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Pathophysiological dual action of adiponectin after transient focal ischemia in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Neuroprotective effects of leptin against ischemic injury induced by oxygen-glucose deprivation and transient cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Body weight after stroke: lessons from the obesity paradox

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Relation between body mass index, waist circumference, and cardiovascular outcomes in 19,579 diabetic patients with established vascular disease: the REACH Registry

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Body Mass Index, Waist Circumference, and Waist-Hip Ratio on the Risk of Total and Type-Specific Stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Biochemical Markers for Blood-Brain Barrier Dysfunction in Acute Ischemic Stroke Correlate with Evolution and Outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0271678X16670411

Elevated C-reactive protein levels in overweight and obese adults

21 January 2018

2 references

https://api.crossref.org/works/10.1177%2F0271678X16670411

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134197

Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134197

Correlation of 99mTc-DTPA SPECT of the blood-brain barrier with neurologic outcome after acute stroke.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134197

The associations of interleukin-6 (IL-6) and downstream inflammatory markers with risk of cardiovascular disease: the Caerphilly Study

27 November 2018

1 reference

12 December 2020

Comparison of numbers of circulating blood monocytes in men grouped by body mass index (<25, 25 to <30, > or =30)

1 reference

12 December 2020

Exaggerated neutrophil-mediated reperfusion injury after ischemic stroke in a rodent model of type 2 diabetes

1 reference

12 December 2020

Cardiovascular disease in Europe: epidemiological update

1 reference

12 December 2020

Influence of obesity on immune function

1 reference

12 December 2020

Relationship of obesity to recanalization after hyperacute recombinant tissue-plasminogen activator infusion therapy in patients with middle cerebral artery occlusion

1 reference

12 December 2020

Body mass index, initial neurological severity and long-term mortality in ischemic stroke

1 reference

12 December 2020

Leukocytosis in obese individuals: possible link in patients with unexplained persistent neutrophilia

1 reference

12 December 2020

Systemic low-grade inflammation is related to both circulating and adipose tissue TNFalpha, leptin and IL-6 levels in obese women

1 reference

12 December 2020

Body fat distribution and insulin resistance

1 reference

12 December 2020

Synergistic benefit of combined amlodipine plus atorvastatin on neuronal damage after stroke in Zucker metabolic rat

1 reference

12 December 2020

Plasma adiponectin levels and five-year survival after first-ever ischemic stroke

1 reference

12 December 2020

Body mass index and death by stroke: no obesity paradox

1 reference

12 December 2020

A useful list of spontaneously arising animal models of obesity and diabetes

1 reference

12 December 2020

The metabolic syndrome is associated with a higher resistance to intravenous thrombolysis for acute ischemic stroke in women than in men

1 reference

12 December 2020

Protection against ischemic stroke damage by synergistic treatment with amlodipine plus atorvastatin in Zucker metabolic rat

1 reference

12 December 2020

Long-term exposure to high fat diet is bad for your brain: exacerbation of focal ischemic brain injury

1 reference

12 December 2020

Relationship of total and abdominal adiposity with CRP and IL-6 in women

1 reference

12 December 2020

Experimental stroke induces massive, rapid activation of the peripheral immune system

1 reference

12 December 2020

Obesity Paradox in the Course of Cerebrovascular Diseases

1 reference

12 December 2020

Obesity paradox or inappropriate study designs? Time for life-course epidemiology

1 reference

12 December 2020