Targeting microenvironment in cancer therapeutics (Q28067219)

cancer-associated fibroblast

main subject

tumor microenvironment

1 reference

8 September 2020

1 reference

8 February 2021

1 reference

inferred from abstract

3

Tao Lu

1 reference

Matthew Martin

1

1 reference

Crossref

Han Wei

series ordinal

2

1 reference

Crossref

language of work or name

1 reference

9 August 2016

4 references

3 April 2019

8 September 2020

8 February 2021

3 references

3 April 2019

8 September 2020

8 February 2021

7

1 reference

issue

32

1 reference

page(s)

52575-52583

1 reference

Creative Commons Attribution 2.5 Generic

copyright license

3 references

Europe PubMed Central

3 April 2019

Europe PubMed Central

8 September 2020

Europe PubMed Central

on focus list of Wikimedia project

8 February 2021

ScienceSource

0 references

cites work

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Slug is a direct Notch target required for initiation of cardiac cushion cellularization

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Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

20 March 2017

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Cancer despite immunosurveillance: immunoselection and immunosubversion

20 March 2017

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Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds

20 March 2017

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Epithelial-mesenchymal transition and its implications for fibrosis

20 March 2017

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

20 March 2017

1 reference

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Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis

20 March 2017

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Epithelial-mesenchymal transitions in tumour progression

20 March 2017

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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

20 March 2017

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20 March 2017

Fibroblasts in cancer

1 reference

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Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

7 April 2017

1 reference

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Tumour-cell invasion and migration: diversity and escape mechanisms

7 April 2017

1 reference

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Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

7 April 2017

1 reference

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Metastasis: from dissemination to organ-specific colonization

7 April 2017

1 reference

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Influence of tumour micro-environment heterogeneity on therapeutic response

7 April 2017

1 reference

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Immunosuppressive networks in the tumour environment and their therapeutic relevance

7 April 2017

1 reference

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IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Helicobacter pylori infection and the risk of gastric carcinoma

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Learning from the "tsunami" of immune checkpoint inhibitors in 2015.

7 April 2017

1 reference

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Notch1 Pathway Activity Determines the Regulatory Role of Cancer-Associated Fibroblasts in Melanoma Growth and Invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Critical role of phosphorylation of serine 165 of YBX1 on the activation of NF-κB in colon cancer

29 September 2017

1 reference

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Role of Novel Serine 316 Phosphorylation of the p65 Subunit of NF-κB in Differential Gene Regulation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

'Cancer associated fibroblasts'--more than meets the eye.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Cancer-associated fibroblasts from hepatocellular carcinoma promote malignant cell proliferation by HGF secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Tumor microenvironment complexity: emerging roles in cancer therapy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Behavior of seeds and soil in the mechanism of metastasis: a deeper understanding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Novel cancer immunotherapy agents with survival benefit: recent successes and next steps

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Cancer associated fibroblasts: the dark side of the coin.

29 September 2017

1 reference

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Lymph node stromal cells enhance drug-resistant colon cancer cell tumor formation through SDF-1α/CXCR4 paracrine signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Role of α(5)β(1) Integrin Up-regulation in Radiation-Induced Invasion by Human Pancreatic Cancer Cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Fusion between Intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Dynamic interplay between the collagen scaffold and tumor evolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Snail is required for TGFbeta-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Seprase: an overview of an important matrix serine protease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Tumor microenvironment and immune escape

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Illuminating the metastatic process

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Cytokines, NF-kappaB, microenvironment, intestinal inflammation and cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Tumour-stroma interaction: cancer-associated fibroblasts as novel targets in anti-cancer therapy?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Posttraumatic inflammation is a complex response based on the pathological expression of the nervous, immune, and endocrine functional systems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Investigating hypoxic tumor physiology through gene expression patterns

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Mechanisms in epithelial plasticity and metastasis: insights from 3D cultures and expression profiling.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Enhanced growth of tumors in SPARC null mice is associated with changes in the ECM.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Colorectal cancer and nonsteroidal anti-inflammatory drugs.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Immunosuppression in human tumor-host interaction: role of cytokines and alterations in signal-transducing molecules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

The role of cytokine mediators in septic shock

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Changing views of the role of matrix metalloproteinases in metastasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Wogonoside induces cell cycle arrest and differentiation by affecting expression and subcellular localization of PLSCR1 in AML cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Off-target activity of TNF-alpha inhibitors characterized by protein biochips

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Dual Role of Mitochondrial Reactive Oxygen Species in Hypoxia Signaling: Activation of Nuclear Factor- B via c-SRC and Oxidant-Dependent Cell Death

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: possible involvement of TNFalpha and IL-1alpha.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5239574

Twisted epithelial-mesenchymal transition blocks senescence

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/27270649

12 December 2020

inferred from PubMed ID database lookup

Expression and growth-promoting function of the IL-8 receptor beta in human melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27270649

12 December 2020

inferred from PubMed ID database lookup

Alterations in NFkappaB activation in T lymphocytes of patients with renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27270649

12 December 2020