The Endothelial Glycocalyx: New Diagnostic and Therapeutic Approaches in Sepsis (Q28072373)

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24 March 2020

review article

2 references

25 January 2021

The Endothelial Glycocalyx: New Diagnostic and Therapeutic Approaches in Sepsis (English)

2 references

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24 March 2020

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25 January 2021

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25 January 2021

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4 August 2019

biomedical investigative technique

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19 September 2019

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11 October 2019

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12 October 2019

1

1 reference

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24 March 2020

Elisabeth Zechendorf

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3

1 reference

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24 March 2020

Tobias Schuerholz

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4

1 reference

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24 March 2020

author name string

Patrick Koczera

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2

2 references

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24 March 2020

language of work or name

1 reference

6 September 2016

6 references

4 August 2019

19 September 2019

11 October 2019

12 October 2019

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24 March 2020

25 January 2021

BioMed Research International

7 references

4 August 2019

19 September 2019

11 October 2019

12 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27699168%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

25 January 2021

2016

2 references

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24 March 2020

page(s)

3758278

2 references

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Creative Commons Attribution 4.0 International

24 March 2020

copyright license

5 references

4 August 2019

19 September 2019

11 October 2019

12 October 2019

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

25 January 2021

0 references

1 reference

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Antimicrobial Peptides in Human Sepsis

20 March 2017

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Choices in fluid type and volume during resuscitation: impact on patient outcomes

20 March 2017

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Severe sepsis and septic shock

20 March 2017

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Clinical utility of biomarkers of endothelial activation in sepsis--a systematic review

20 March 2017

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Systemic Steroids in Severe Sepsis and Septic Shock

20 March 2017

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20 March 2017

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Inflammation- and ischemia-induced shedding of venular glycocalyx

20 March 2017

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20 March 2017

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The Synthetic Antimicrobial Peptide 19-2.5 Interacts with Heparanase and Heparan Sulfate in Murine and Human Sepsis

7 April 2017

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Soluble Heparan Sulfate in Serum of Septic Shock Patients Induces Mitochondrial Dysfunction in Murine Cardiomyocytes

29 September 2017

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Endothelial cell-specific molecule-1/endocan: Diagnostic and prognostic value in patients suffering from severe sepsis and septic shock

29 September 2017

1 reference

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Role of pulmonary microvascular endothelial cell apoptosis in murine sepsis-induced lung injury in vivo

29 September 2017

1 reference

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Advances in Sepsis Research

29 September 2017

1 reference

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Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by inhibiting heparanase

29 September 2017

1 reference

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Peptide 19-2.5 inhibits heparan sulfate-triggered inflammation in murine cardiomyocytes stimulated with human sepsis serum

29 September 2017

1 reference

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Characteristics of serum endocan levels in infection

29 September 2017

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Evaluation of endothelial biomarkers as predictors of organ failures in septic shock patients

29 September 2017

1 reference

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Hypervolemia increases release of atrial natriuretic peptide and shedding of the endothelial glycocalyx

29 September 2017

1 reference

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Soluble heparan sulfate fragments generated by heparanase trigger the release of pro-inflammatory cytokines through TLR-4.

29 September 2017

1 reference

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N-acetyl-heparin attenuates acute lung injury caused by acid aspiration mainly by antagonizing histones in mice

29 September 2017

1 reference

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The endothelial glycocalyx: a review of the vascular barrier

29 September 2017

1 reference

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Heparanase mediates renal dysfunction during early sepsis in mice.

29 September 2017

1 reference

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Versatile role of heparanase in inflammation

29 September 2017

1 reference

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Preclinical investigations reveal the broad-spectrum neutralizing activity of peptide Pep19-2.5 on bacterial pathogenicity factors

29 September 2017

1 reference

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The anti-inflammatory effect of the synthetic antimicrobial peptide 19-2.5 in a murine sepsis model: a prospective randomized study

29 September 2017

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Neutrophil extracellular traps: double-edged swords of innate immunity

29 September 2017

1 reference

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The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis.

29 September 2017

1 reference

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Lest we forget the endothelial glycocalyx in sepsis

29 September 2017

1 reference

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A new class of synthetic peptide inhibitors blocks attachment and entry of human pathogenic viruses

29 September 2017

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Antimicrobial peptides and their potential application in inflammation and sepsis

29 September 2017

1 reference

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The function of neutrophils in sepsis

29 September 2017

1 reference

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Significance of heparanase in cancer and inflammation

29 September 2017

1 reference

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Heparanase levels are elevated in the urine and plasma of type 2 diabetes patients and associate with blood glucose levels

29 September 2017

1 reference

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The effect of inflammation on coagulation and vice versa

29 September 2017

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New antiseptic peptides to protect against endotoxin-mediated shock

29 September 2017

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Therapeutic strategies targeting the endothelial glycocalyx: acute deficits, but great potential

29 September 2017

1 reference

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Endothelial glycocalyx as potential diagnostic and therapeutic target in cardiovascular disease

29 September 2017

1 reference

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Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients

29 September 2017

1 reference

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The structure and function of the endothelial glycocalyx layer

29 September 2017

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Heparanase expression in malignant salivary gland tumors inversely correlates with long-term survival

29 September 2017

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The endothelial glycocalyx: a potential barrier between health and vascular disease

29 September 2017

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International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics

29 September 2017

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Inflammatory cytokines and fatty acids regulate endothelial cell heparanase expression

29 September 2017

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Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Inflammation-induced increases in plasma endocan levels are associated with endothelial dysfunction in humans in vivo

2 June 2018

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Release of atrial natriuretic peptide precedes shedding of the endothelial glycocalyx equally in patients undergoing on- and off-pump coronary artery bypass surgery

2 June 2018

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2 June 2018

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Fluorescence correlation spectroscopy can probe albumin dynamics inside lung endothelial glycocalyx

2 June 2018

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The ancient riddle of sigma eta psi iota sigma (sepsis).

2 June 2018

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Coagulopathy, catecholamines, and biomarkers of endothelial damage in experimental human endotoxemia and in patients with severe sepsis: a prospective study

2 June 2018

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Vascular adhesion protein-1 and syndecan-1 in septic shock

21 January 2018

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Circulating glycosaminoglycan species in septic shock

21 January 2018

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Shedding of the coronary endothelial glycocalyx: effects of hypoxia/reoxygenation vs ischaemia/reperfusion

21 January 2018

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Characterization and binding activity of the chondroitin/dermatan sulfate chain from Endocan, a soluble endothelial proteoglycan

21 January 2018

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Elevated serum angiopoietin 2 levels are associated with increased mortality in sepsis

21 January 2018

1 reference

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Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis

21 January 2018

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Hydrocortisone preserves the vascular barrier by protecting the endothelial glycocalyx

21 January 2018

1 reference

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Stress doses of hydrocortisone reduce severe systemic inflammatory response syndrome and improve early outcome in a risk group of patients after cardiac surgery.

21 January 2018

1 reference

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Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial.

21 January 2018

1 reference

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Contrasting effects of colloid and crystalloid resuscitation fluids on cardiac vascular permeability

21 January 2018

1 reference

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Albumin replacement in patients with severe sepsis or septic shock

21 January 2018

1 reference

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Endocan, a new endothelial marker in human sepsis

21 January 2018

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12 December 2020

Low-dose hydrocortisone during severe sepsis: effects on microalbuminuria

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12 December 2020

Perioperative Statins in Cardiac Surgery and Acute Kidney Injury

1 reference

12 December 2020

Sepsis and major abdominal surgery lead to flaking of the endothelial glycocalix

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12 December 2020

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Angiopoietin-2 is increased in septic shock: Evidence for the existence of a circulating factor stimulating its release from human monocytes

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Identifiers

DOI

10.1155/2016/3758278

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27699168%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27699168%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

PubMed publication ID

27699168

2 references