Cytotoxic CD4 T Cells: Differentiation, Function, and Application to Dengue Virus Infection (Q28079626)

language of work or name

1 reference

7 December 2016

1 reference

published in

Frontiers in Immunology

1 reference

volume

7

1 reference

page(s)

531

1 reference

Functional classification of memory CD8(+) T cells by CX3CR1 expression

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A Context-Dependent Role for IL-21 in Modulating the Differentiation, Distribution, and Abundance of Effector and Memory CD8 T Cell Subsets.

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Cytomegalovirus-Specific CD4 T Cells Are Cytolytic and Mediate Vaccine Protection

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Dengue virus infection elicits highly polarized CX3CR1+ cytotoxic CD4+ T cells associated with protective immunity

29 September 2017

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Type I IFNs and IL-18 regulate the antiviral response of primary human γδ T cells against dendritic cells infected with Dengue virus

29 September 2017

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Regulation of CD4 and CD8 coreceptor expression and CD4 versus CD8 lineage decisions

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T cell memory. A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells

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A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells

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T-cell immunity to infection with dengue virus in humans

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29 September 2017

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CD4 CTL: living up to the challenge

29 September 2017

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Cytokine-dependent induction of CD4+ T cells with cytotoxic potential during influenza virus infection

29 September 2017

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The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells

29 September 2017

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Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells

29 September 2017

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Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin

29 September 2017

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Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Perforin-dependent CD4+ T-cell cytotoxicity contributes to control a murine poxvirus infection

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

29 September 2017

1 reference

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The zinc finger transcription factor Zbtb7b represses CD8-lineage gene expression in peripheral CD4+ T cells

29 September 2017

1 reference

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Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination

29 September 2017

1 reference

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29 September 2017

1 reference

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Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance

29 September 2017

1 reference

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Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5141332

HLA-A, -B, -C, and -DRB1 allele frequencies in Cuban individuals with antecedents of dengue 2 disease: advantages of the Cuban population for HLA studies of dengue virus infection

29 September 2017

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Yellow fever: epidemiology and prevention

29 September 2017

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Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation.

29 September 2017

1 reference

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Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation

29 September 2017

1 reference

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STAT5-mediated signals sustain a TCR-initiated gene expression program toward differentiation of CD8 T cell effectors

29 September 2017

1 reference

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Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin

29 September 2017

1 reference

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Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes

29 September 2017

1 reference

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Human T regulatory cells can use the perforin pathway to cause autologous target cell death

29 September 2017

1 reference

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STAT2 nuclear trafficking

29 September 2017

1 reference

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Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization

29 September 2017

1 reference

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HLA-DR antigen frequencies in Mexican patients with dengue virus infection: HLA-DR4 as a possible genetic resistance factor for dengue hemorrhagic fever.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5141332

Dual functions of fractalkine/CX3C ligand 1 in trafficking of perforin+/granzyme B+ cytotoxic effector lymphocytes that are defined by CX3CR1 expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5141332

Definition of an epitope on NS3 recognized by human CD4+ cytotoxic T lymphocyte clones cross-reactive for dengue virus types 2, 3, and 4.

29 September 2017

1 reference

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Fas-dependent CD4+ cytotoxic T-cell-mediated pathogenesis during virus infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5141332

CD1: presenting unusual antigens to unusual T lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5141332

Multifunctional CD4 cells expressing gamma interferon and perforin mediate protection against lethal influenza virus infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5141332

Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5141332

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5141332

CD4 engagement by CD1d potentiates activation of CD4+ invariant NKT cells.

2 June 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2016.00531

IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2016.00531

IL-21 promotes CD8+ CTL activity via the transcription factor T-bet

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2016.00531

Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2016.00531

Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2016.00531

Emergence of a CD4+CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2016.00531

Characteristics of expanded CD4+CD28null T cells in patients with chronic hepatitis B.

21 January 2018

1 reference

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CD4(+)CD8(dim) T lymphocytes exhibit enhanced cytokine expression, proliferation and cytotoxic activity in response to HCMV and HIV-1 antigens.

21 January 2018

1 reference

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Cutting edge: MHC class II-restricted killing in vivo during viral infection

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/28003809

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterization of CD4(+) CTLs ex vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/28003809

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28003809

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FIMMU.2016.00531

0 references

1 reference

PubMed publication ID

28003809

1 reference