Tumor Suppressor Inactivation in the Pathogenesis of Adult T-Cell Leukemia (Q28081287)

language of work or name

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2015

1 reference

1 reference

2015

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page(s)

183590

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Creative Commons Attribution 3.0 Unported

copyright license

start time

1 January 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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April 2022 Public Data File from Crossref

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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The INK4-ARF (CDKN2A/B) locus in hematopoiesis and BCR-ABL-induced leukemias

29 September 2017

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29 September 2017

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Critical role for TSLC1 expression in the growth and organ infiltration of adult T-cell leukemia cells in vivo

29 September 2017

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Control of cell proliferation pathways by microRNAs

29 September 2017

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29 September 2017

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MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

29 September 2017

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Human T-cell leukemia virus type 1 tax attenuates the ATM-mediated cellular DNA damage response

29 September 2017

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MicroRNAs 221 and 222 bypass quiescence and compromise cell survival

29 September 2017

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PAX3-FOXO1 controls expression of the p57Kip2 cell-cycle regulator through degradation of EGR1.

29 September 2017

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Centrosome amplification in adult T-cell leukemia and human T-cell leukemia virus type 1 Tax-induced human T cells

29 September 2017

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Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence

29 September 2017

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HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells

29 September 2017

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Human T-cell leukemia virus type 1 Tax attenuates gamma-irradiation-induced apoptosis through physical interaction with Chk2.

29 September 2017

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29 September 2017

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Overexpression of a cell adhesion molecule, TSLC1, as a possible molecular marker for acute-type adult T-cell leukemia

29 September 2017

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Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-I-transformed cells

29 September 2017

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HTLV-I Tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity

29 September 2017

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Emmprin, a cell surface inducer of matrix metalloproteinases (MMPs), is expressed in T-cell lymphomas

29 September 2017

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Human T-lymphotropic virus type 1 oncoprotein tax promotes unscheduled degradation of Pds1p/securin and Clb2p/cyclin B1 and causes chromosomal instability

29 September 2017

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Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia

29 September 2017

1 reference

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Human T-cell leukemia virus type I Tax transactivates the matrix metalloproteinase-9 gene: potential role in mediating adult T-cell leukemia invasiveness

29 September 2017

1 reference

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Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer

29 September 2017

1 reference

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Suppression of DNA repair by HTLV type 1 Tax correlates with Tax trans-activation of proliferating cell nuclear antigen gene expression

29 September 2017

1 reference

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Human T-lymphotropic virus type I Tax protein utilizes distinct pathways for p53 inhibition that are cell type-dependent.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter

29 September 2017

1 reference

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Overexpression of p21(waf1) in human T-cell lymphotropic virus type 1-infected cells and its association with cyclin A/cdk2.

29 September 2017

1 reference

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Bcl-X(L) is up-regulated by HTLV-I and HTLV-II in vitro and in ex vivo ATLL samples

29 September 2017

1 reference

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p53 stabilization and functional impairment in the absence of genetic mutation or the alteration of the p14(ARF)-MDM2 loop in ex vivo and cultured adult T-cell leukemia/lymphoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Deletion of the p16INK4A gene in ex vivo acute adult T cell lymphoma/leukemia cells and methylation of the p16INK4A promoter in HTLV type I-infected T cell lines.

29 September 2017

1 reference

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Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation.

29 September 2017

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Expression and phosphorylation status of retinoblastoma protein in adult T-cell leukemia/lymphoma

29 September 2017

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29 September 2017

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Down-regulation of the INK4 family of cyclin-dependent kinase inhibitors by tax protein of HTLV-1 through two distinct mechanisms

29 September 2017

1 reference

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Defective DNA repair in cells with human T-cell leukemia/bovine leukemia viruses: role of tax gene

29 September 2017

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Limiting amounts of p27Kip1 correlates with constitutive activation of cyclin E-CDK2 complex in HTLV-I-transformed T-cells

29 September 2017

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Disruption of nucleotide excision repair by the human T-cell leukemia virus type 1 Tax protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Human T-cell lymphotropic/leukemia virus type 1 Tax abrogates p53-induced cell cycle arrest and apoptosis through its CREB/ATF functional domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Inhibition of p53 transactivation function by the human T-cell lymphotropic virus type 1 Tax protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Aberrant expression and function of p53 in T-cells immortalized by HTLV-I Tax1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

HTLV-1 Tax protein interacts with cyclin-dependent kinase inhibitor p16INK4A and counteracts its inhibitory activity towards CDK4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

A survey of human leukaemias for sequences of a human retrovirus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Clinical diversity in adult T-cell leukemia-lymphoma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Chromosome abnormalities in adult T-cell leukemia/lymphoma: a karyotype review committee report

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Multi-step aberrant CpG island hyper-methylation is associated with the progression of adult T-cell leukemia/lymphoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Inhibition of caspase cascade by HTLV-I tax through induction of NF-kappaB nuclear translocation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Critical role for the 310 helix region of p57(Kip2) in cyclin-dependent kinase 2 inhibition and growth suppression

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Microsatellite instability in adult T-cell leukaemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Role of E2F in cell cycle control and cancer

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Aberrant expression of the p53 tumor suppressor gene in adult T-cell leukemia and HTLV-I-infected cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Stabilization of wild-type p53 in human T-lymphocytes transformed by HTLV-I.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Alterations of the p27KIP1 gene in non-Hodgkin's lymphomas and adult T-cell leukemia/lymphoma

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma. A report from the Lymphoma Study Group (1984-87).

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Structural and functional analysis of oncogenes and tumor suppressor genes in adult T-cell leukemia/lymphoma shows frequent p53 mutations

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Correlation of telomerase activity with development and progression of adult T-cell leukemia.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

How I treat adult T-cell leukemia/lymphoma.

20 June 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Genetic Alteration of p53 in Some Patients with Adult T-Cell Leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Polycomb-mediated loss of miR-31 activates NIK-dependent NF-κB pathway in adult T cell leukemia and other cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Human T-cell leukemia virus type I tax repression of p73beta is mediated through competition for the C/H1 domain of CBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Functional impairment of p73 and p51, the p53-related proteins, by the human T-cell leukemia virus type 1 Tax oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

CDKN2 (MTS1/p16INK4A) gene alterations in adult T-cell leukemia/lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Genetic mutation and early onset of T-cell leukemia in pediatric patients infected at birth with HTLV-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

CDKN2A germline mutations in familial pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

MicroRNA 92b controls the G1/S checkpoint gene p57 in human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Mutations in the retinoblastoma-related gene RB2/p130 in adult T-cell leukaemia/lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

MicroRNA-21 accelerates hepatocyte proliferation in vitro via PI3K/Akt signaling by targeting PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Cytogenetic analysis and clinical significance in adult T-cell leukemia/lymphoma: a study of 50 cases from the human T-cell leukemia virus type-1 endemic area, Nagasaki

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Reduced expression of human mismatch repair genes in adult T-cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Meta-Analysis on the Use of Zidovudine and Interferon-Alfa in Adult T-Cell Leukemia/Lymphoma Showing Improved Survival in the Leukemic Subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Mutations in theINK4a/ARFMelanoma Susceptibility Locus Functionally Impair p14ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Mutational analysis of the hMSH2 gene in a wide variety of tumors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Epigenetic inactivation of the WNT antagonist SFRP1 in breast cancer

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Homozygous deletions of the p15 (MTS2) and p16 (CDKN2/MTS1) genes in adult T-cell leukemia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478360

Human p53 gene localized to short arm of chromosome 17

27 November 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F183590

Mutations of the p53 gene in adult T-cell leukemia

21 January 2018

1 reference

12 December 2020

Microsatellite instability as a potential marker for poor prognosis in adult T cell leukemia/lymphoma

1 reference

12 December 2020

Extensive analysis of the retinoblastoma gene in adult T cell leukemia/lymphoma (ATL)

1 reference

12 December 2020

TP53is frequently altered by methylation, mutation, and/or deletion in acute lymphoblastic leukaemia

1 reference

12 December 2020

p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent

1 reference

12 December 2020

Inactivation of multiple tumor-suppressor genes involved in negative regulation of the cell cycle, MTS1/p16INK4A/CDKN2, MTS2/p15INK4B, p53, and Rb genes in primary lymphoid malignancies

1 reference

12 December 2020

Interaction of HTLV-1 Tax with minichromosome maintenance proteins accelerates the replication timing program

1 reference

12 December 2020

A retrovirus from human leukemia cell lines: its isolation, characterization, and implication in human adult T-cell leukemia (ATL)

1 reference

12 December 2020

Impact of p53 aberration on the progression of Adult T-cell Leukemia/Lymphoma

1 reference

12 December 2020

Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation

1 reference

12 December 2020

Identifiers

1 reference

1 reference

PubMed publication ID

26170835

1 reference