Models in biology: lessons from modeling regulation of the eukaryotic cell cycle (Q28082725)

main subject

physiological phenomenon

1 reference

biomedical investigative technique

20 August 2019

1 reference

19 September 2019

1 reference

12 October 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26129844%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

author name string

John J Tyson

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26129844%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

language of work or name

1 reference

1 July 2015

4 references

20 August 2019

19 September 2019

12 October 2019

4 references

20 August 2019

19 September 2019

12 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26129844%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

volume

13

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26129844%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

issue

1

0 references

page(s)

46

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26129844%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

14 June 2020

copyright license

3 references

20 August 2019

19 September 2019

12 October 2019

0 references

The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

An amplified sensitivity arising from covalent modification in biological systems

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Universal control mechanism regulating onset of M-phase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Bistability, oscillations, and traveling waves in frog egg extracts

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Models in biology: 'accurate descriptions of our pathetic thinking'.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Role for regulated phosphatase activity in generating mitotic oscillations in Xenopus cell-free extracts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Mitotic trigger waves and the spatial coordination of the Xenopus cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

The Cdk1-APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Testing a mathematical model of the yeast cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Kinetic analysis of a molecular model of the budding yeast cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Modeling M-phase control in Xenopus oocyte extracts: the surveillance mechanism for unreplicated DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Modeling the control of DNA replication in fission yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Control of the Cdc2/cyclin B complex in Xenopus egg extracts arrested at a G2/M checkpoint with DNA synthesis inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Cell cycle dynamics of an M-phase-specific cytoplasmic factor in Xenopus laevis oocytes and eggs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Purification of maturation-promoting factor, an intracellular regulator of early mitotic events

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Dominoes and clocks: the union of two views of the cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Cyclin synthesis drives the early embryonic cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Cyclin is a component of maturation-promoting factor from Xenopus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Modeling the cell division cycle: cdc2 and cyclin interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

The BEG (PP2A-B55/ENSA/Greatwall) pathway ensures cytokinesis follows chromosome separation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Adaptation to the spindle checkpoint is regulated by the interplay between Cdc28/Clbs and PP2ACdc55

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Greatwall maintains mitosis through regulation of PP2A.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Irreversibility of mitotic exit is the consequence of systems-level feedback.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Irreversible cell-cycle transitions are due to systems-level feedback.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Greatwall kinase participates in the Cdc2 autoregulatory loop in Xenopus egg extracts

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Numerical analysis of a comprehensive model of M-phase control in Xenopus oocyte extracts and intact embryos.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Cyclin activation of p34cdc2.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

A Model for the Adjustment of the Mitotic Clock by Cyclin and MPF Levels

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486427

Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12915-015-0158-9

Sli15(INCENP) dephosphorylation prevents mitotic checkpoint reengagement due to loss of tension at anaphase onset

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12915-015-0158-9

Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26129844

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S12915-015-0158-9

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26129844%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

14 June 2020

1033830607

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26129844%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

PubMed publication ID

26129844

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26129844%20AND%20SRC:MED&resulttype=core&format=json