Asymmetric dimethylarginine and cardiovascular risk: systematic review and meta-analysis of 22 prospective studies (Q28087272)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26021436%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Jari A. Laukkanen

3

1 reference

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12 June 2020

Manuel Mayr

6

1 reference

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12 June 2020

Emanuele Di Angelantonio

7

1 reference

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12 June 2020

author name string

Daniel F Freitag

2

1 reference

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12 June 2020

Susmita Chowdhury

4

1 reference

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12 June 2020

Reeta Gobin

5

1 reference

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12 June 2020

Rajiv Chowdhury

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26021436%20AND%20SRC:MED&resulttype=core&format=json

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

12 June 2020

language of work or name

1 reference

28 May 2015

3 references

17 June 2019

19 November 2019

4 references

17 June 2019

19 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26021436%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

4

2 references

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12 June 2020

issue

6

2 references

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12 June 2020

page(s)

e001833

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26021436%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 4.0 International

12 June 2020

copyright license

2 references

17 June 2019

Disruption of methylarginine metabolism impairs vascular homeostasis

19 November 2019

cites work

1 reference

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Measuring inconsistency in meta-analyses

20 March 2017

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Bias in meta-analysis detected by a simple, graphical test

20 March 2017

1 reference

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Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

20 March 2017

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The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

20 March 2017

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Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine

7 April 2017

1 reference

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Incidence of all-cause and cardiovascular mortality predicted by symmetric dimethylarginine in the population-based study of health in pomerania

29 September 2017

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Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality

29 September 2017

1 reference

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Asymmetric dimethylarginine predicts survival in the elderly

29 September 2017

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Omega-3 Status and the Relationship between Plasma Asymmetric Dimethylarginine and Risk of Myocardial Infarction in Patients with Suspected Coronary Artery Disease

29 September 2017

1 reference

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Circulating levels of dimethylarginines, chronic kidney disease and long-term clinical outcome in non-ST-elevation myocardial infarction.

29 September 2017

1 reference

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Asymmetric and symmetric dimethylarginine and risk of secondary cardiovascular disease events and mortality in patients with stable coronary heart disease: the KAROLA follow-up study

29 September 2017

1 reference

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Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators?

29 September 2017

1 reference

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Association of circulating levels of asymmetric dimethylarginine (ADMA) with carotid intima-media thickness: evidence from 6168 participants

29 September 2017

1 reference

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Effect of oral L-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials

29 September 2017

1 reference

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The therapeutic potential of targeting endogenous inhibitors of nitric oxide synthesis.

29 September 2017

1 reference

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The role of asymmetric and symmetric dimethylarginines in renal disease

29 September 2017

1 reference

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Asymmetric dimethylarginine correlates with measures of disease severity, major adverse cardiovascular events and all-cause mortality in patients with peripheral arterial disease.

29 September 2017

1 reference

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Oral L-arginine supplementation in acute myocardial infarction therapy: a meta-analysis of randomized controlled trials

29 September 2017

1 reference

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Association of plasma ADMA levels with MRI markers of vascular brain injury: Framingham offspring study

29 September 2017

1 reference

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Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition

29 September 2017

1 reference

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Asymmetric dimethylarginine and mortality in stages 3 to 4 chronic kidney disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community

29 September 2017

1 reference

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Increase in fasting vascular endothelial function after short-term oral L-arginine is effective when baseline flow-mediated dilation is low: a meta-analysis of randomized controlled trials

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Plasma asymmetric dimethylarginine and cardiovascular events in patients with acute decompensated heart failure

29 September 2017

1 reference

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A critical review and discussion of analytical methods in the L-arginine/nitric oxide area of basic and clinical research

29 September 2017

1 reference

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Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine predict adverse events in patients undergoing noncardiac surgery

29 September 2017

1 reference

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Asymmetric dimethylarginine, smoking, and risk of coronary heart disease in apparently healthy men: prospective analysis from the population-based Monitoring of Trends and Determinants in Cardiovascular Disease/Kooperative Gesundheitsforschung in de

29 September 2017

1 reference

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Symmetric dimethylarginine (SDMA) as endogenous marker of renal function--a meta-analysis

29 September 2017

1 reference

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Analysis of N-terminal-pro-brain natriuretic peptide and C-reactive protein for risk stratification in stable and unstable coronary artery disease: results from the AtheroGene study.

29 September 2017

1 reference

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Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence

29 September 2017

1 reference

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The emerging role of asymmetric dimethylarginine as a novel cardiovascular risk factor

29 September 2017

1 reference

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Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies

29 September 2017

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Nitric oxide: an endogenous modulator of leukocyte adhesion

29 September 2017

1 reference

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Asymmetrical dimethylarginine is associated with renal and cardiovascular outcomes and all-cause mortality in renal transplant recipients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Methylarginines and mortality in patients with end stage renal disease: a prospective cohort study.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Asymmetric dimethylarginine enhances cardiovascular risk prediction in patients with chronic heart failure.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Dysfunctional nitric oxide signalling increases risk of myocardial infarction

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Symmetrical dimethylarginine predicts mortality in the general population: observations from the Dallas heart study

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Endothelial dysfunction, inflammation and malnutrition markers as predictors of mortality in dialysis patients: multimarker approach.

27 November 2018

1 reference

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Ramipril sensitizes platelets to nitric oxide: implications for therapy in high-risk patients.

27 November 2018

1 reference

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Plasma asymmetric dimethylarginine predicts death and major adverse cardiovascular events in individuals referred for coronary angiography.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Symmetric dimethylarginine is a marker of detrimental outcome in the acute phase after ischaemic stroke: role of renal function.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Circulating levels of asymmetric dimethylarginine are an independent risk factor for left ventricular hypertrophy and predict cardiovascular events in pre-dialysis patients with chronic kidney disease

27 November 2018

1 reference

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Traditional and nontraditional risk factors as predictors of cerebrovascular events in patients with end stage renal disease

27 November 2018

1 reference

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Levels of asymmetrical dimethylarginine are predictive of brachial artery flow-mediated dilation 6 years later. The Cardiovascular Risk in Young Finns Study

27 November 2018

1 reference

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A novel loss-of-function DDAH1 promoter polymorphism is associated with increased susceptibility to thrombosis stroke and coronary heart disease.

27 November 2018

1 reference

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A novel predictor of restenosis and adverse cardiac events: asymmetric dimethylarginine

27 November 2018

1 reference

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Relation of baseline plasma ADMA levels to cardiovascular morbidity and mortality at two years in men with diabetes mellitus referred for coronary angiography.

27 November 2018

1 reference

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Relationship of baseline plasma ADMA levels to cardiovascular outcomes at 2 years in men with acute coronary syndrome referred for coronary angiography.

27 November 2018

1 reference

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Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Asymmetric dimethylarginine independently predicts fatal and nonfatal myocardial infarction and stroke in women: 24-year follow-up of the population study of women in Gothenburg

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Plasma concentration of asymmetric dimethylarginine (ADMA) predicts cardiovascular morbidity and mortality in type 1 diabetic patients with diabetic nephropathy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

ADMA is independently related to flow-mediated vasodilation in subjects at low cardiovascular risk.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Asymmetric dimethylarginine, cortisol/cortisone ratio, and C-peptide: markers for diabetes and cardiovascular risk?

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Regression dilution methods for meta-analysis: assessing long-term variability in plasma fibrinogen among 27,247 adults in 15 prospective studies.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Asymmetrical (ADMA) and symmetrical dimethylarginine (SDMA) as potential risk factors for cardiovascular and renal outcome in chronic kidney disease - possible candidates for paradoxical epidemiology?

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Asymmetric dimethylarginine induces apoptosis via p38 MAPK/caspase-3-dependent signaling pathway in endothelial cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Low dialysance of asymmetric dimethylarginine (ADMA)--in vivo and in vitro evidence of significant protein binding

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Plasma levels of asymmetrical dimethylarginine and adverse cardiovascular events after percutaneous coronary intervention

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

Plasma concentration of asymmetrical dimethylarginine and mortality in patients with end-stage renal disease: a prospective study.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599532

An endogenous inhibitor of nitric oxide synthase regulates endothelial adhesiveness for monocytes

27 November 2018

1 reference

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Explaining heterogeneity in meta-analysis: a comparison of methods.

27 November 2018

1 reference

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Asymmetric dimethylarginine predicts cardiovascular events in patients with type 2 diabetes

27 November 2018

1 reference

12 December 2020

Dietary l-arginine decreases myointimal cell proliferation and vascular monocyte accumulation in cholesterol-fed rabbits

1 reference

12 December 2020

Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production

1 reference

12 December 2020

Asymmetric dimethylarginine determines the improvement of endothelium-dependent vasodilation by simvastatin: Effect of combination with oral L-arginine

1 reference

12 December 2020

Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1

1 reference

12 December 2020

Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis

1 reference

12 December 2020

Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2

1 reference

12 December 2020

Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study

1 reference

12 December 2020

Asymmetric dimethylarginine predicts major adverse cardiovascular events in patients with advanced peripheral artery disease

1 reference

12 December 2020

Asymmetric dimethylarginine as an independent risk marker for mortality in ambulatory patients with peripheral arterial disease

1 reference

12 December 2020

Asymmetric dimethylarginine increases mononuclear cell adhesiveness in hypercholesterolemic humans

1 reference

12 December 2020

Association of homocysteine and asymmetric dimethylarginine with atherosclerosis and cardiovascular events in maintenance hemodialysis patients

1 reference

12 December 2020

Identifiers

DOI

10.1161/JAHA.115.001833

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26021436%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26021436%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26021436%20AND%20SRC:MED&resulttype=core&format=json