Future technology insight: mass spectrometry imaging as a tool in drug research and development (Q28087460)

21 June 2017

1 reference

title

Future technology insight: mass spectrometry imaging as a tool in drug research and development (English)

1 reference

21 June 2017

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766375%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

D F Cobice

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766375%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

R J A Goodwin

2

1 reference

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6 June 2020

P E Andren

3

1 reference

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6 June 2020

A Nilsson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766375%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

C L Mackay

5

1 reference

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6 June 2020

language of work or name

1 reference

5 May 2015

1 reference

25766375

British Journal of Pharmacology

21 June 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766375%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

172

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6 June 2020

issue

13

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6 June 2020

page(s)

3266-3283

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766375%20AND%20SRC:MED&resulttype=core&format=json

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

6 June 2020

cites work

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29 September 2017

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Whole-body and microscopic autoradiography to determine tissue distribution of biopharmaceuticals -- target discoveries with receptor micro-autoradiography engendered new concepts and therapies for vitamin D.

29 September 2017

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Deuterated matrix-assisted laser desorption ionization matrix uncovers masked mass spectrometry imaging signals of small molecules

29 September 2017

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29 September 2017

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Quantitative mass spectrometry imaging of propranolol and olanzapine using tissue extinction calculation as normalization factor

29 September 2017

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Conductive carbon tape used for support and mounting of both whole animal and fragile heat-treated tissue sections for MALDI MS imaging and quantitation.

29 September 2017

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Sample preparation for mass spectrometry imaging: small mistakes can lead to big consequences

29 September 2017

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Evaluation of the Bruker Biotyper and Vitek MS matrix-assisted laser desorption ionization-time of flight mass spectrometry systems for identification of nonfermenting gram-negative bacilli isolated from cultures from cystic fibrosis patients

29 September 2017

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Diagnosing the decline in pharmaceutical R&D efficiency

29 September 2017

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The significance of ambient-temperature on pharmaceutical and endogenous compound abundance and distribution in tissues sections when analyzed by matrix-assisted laser desorption/ionization mass spectrometry imaging

29 September 2017

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Tissue imaging using nanospray desorption electrospray ionization mass spectrometry

29 September 2017

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MALDI imaging mass spectrometry: bridging biology and chemistry in drug development

29 September 2017

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29 September 2017

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Reagent precoated targets for rapid in-tissue derivatization of the anti-tuberculosis drug isoniazid followed by MALDI imaging mass spectrometry

29 September 2017

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On-tissue chemical derivatization of 3-methoxysalicylamine for MALDI-imaging mass spectrometry

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Mass spectrometry imaging of pharmacological compounds in tissue sections

29 September 2017

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29 September 2017

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Relationship between MALDI IMS Intensity and Measured Quantity of Selected Phospholipids in Rat Brain Sections

29 September 2017

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Laser ablation electrospray ionization for atmospheric pressure molecular imaging mass spectrometry

29 September 2017

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A solvent-free matrix application method for matrix-assisted laser desorption/ionization imaging of small molecules.

29 September 2017

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Mass spectrometric imaging for biomedical tissue analysis

29 September 2017

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Study of matrix additives for sensitive analysis of lipid A by matrix-assisted laser desorption ionization mass spectrometry

29 September 2017

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Use of a solvent-free dry matrix coating for quantitative matrix-assisted laser desorption ionization imaging of 4-bromophenyl-1,4-diazabicyclo(3.2.2)nonane-4-carboxylate in rat brain and quantitative analysis of the drug from laser [...]

29 September 2017

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29 September 2017

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29 September 2017

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Developments in molecular SIMS depth profiling and 3D imaging of biological systems using polyatomic primary ions

29 September 2017

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Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development

29 September 2017

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29 September 2017

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29 September 2017

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Towards a second generation of ionic liquid matrices (ILMs) for MALDI-MS of peptides, proteins, and carbohydrates

29 September 2017

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29 September 2017

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Sample preparation issues for tissue imaging by imaging MS.

29 September 2017

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Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections

29 September 2017

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Nanostructure initiator mass spectrometry: tissue imaging and direct biofluid analysis

29 September 2017

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Mass spectrometric imaging of lipids using desorption electrospray ionization

29 September 2017

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Time-dependent evolution of tissue markers by MALDI-MS imaging

29 September 2017

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SIMS and MALDI MS imaging of the spinal cord

29 September 2017

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High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry

29 September 2017

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Desorption electrospray ionization mass spectrometry: Imaging drugs and metabolites in tissues

29 September 2017

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Recent developments in PET detector technology

29 September 2017

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MALDI-FTICR imaging mass spectrometry of drugs and metabolites in tissue

29 September 2017

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Imaging MALDI mass spectrometry using an oscillating capillary nebulizer matrix coating system and its application to analysis of lipids in brain from a mouse model of Tay-Sachs/Sandhoff disease

29 September 2017

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Tissue concentrations: do we ever learn?

29 September 2017

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Imaging of a beta-peptide distribution in whole-body mice sections by MALDI mass spectrometry

29 September 2017

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Bioimaging TOF-SIMS: High resolution 3D imaging of single cells.

29 September 2017

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Suppression and enhancement of secondary ion formation due to the chemical environment in static-secondary ion mass spectrometry

29 September 2017

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Imaging mass spectrometry at cellular length scales

29 September 2017

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Anti-inflammatory agent indomethacin reduces invasion and alters metabolism in a human breast cancer cell line

29 September 2017

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Examination of the distribution of the bioreductive drug AQ4N and its active metabolite AQ4 in solid tumours by imaging matrix-assisted laser desorption/ionisation mass spectrometry

29 September 2017

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The application of cassette dosing for pharmacokinetic screening in small-molecule cancer drug discovery

29 September 2017

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Mass measurement accuracy in analyses of highly complex mixtures based upon multidimensional recalibration

29 September 2017

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Tissue imaging at atmospheric pressure using desorption electrospray ionization (DESI) mass spectrometry

29 September 2017

1 reference

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Optimizing UV laser focus profiles for improved MALDI performance

29 September 2017

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Matrix-assisted laser desorption/ionization imaging mass spectrometry for direct measurement of clozapine in rat brain tissue

29 September 2017

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Decreased striatal levels of PEP-19 following MPTP lesion in the mouse

29 September 2017

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PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

29 September 2017

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Drug tissue distribution: study methods and therapeutic implications

29 September 2017

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MALDI mass spectrometry for direct tissue analysis: a new tool for biomarker discovery

29 September 2017

1 reference

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Analysis of protein glycation products by MALDI-TOF/MS.

29 September 2017

1 reference

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MALDI mass spectrometry analysis of high molecular weight proteins from whole bacterial cells: pretreatment of samples with surfactants

29 September 2017

1 reference

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Imaging mass spectrometry: fundamentals and applications to drug discovery

29 September 2017

1 reference

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Three-dimensional visualization of protein expression in mouse brain structures using imaging mass spectrometry.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Determination of oligonucleotide molecular masses by MS-MALDI

29 September 2017

1 reference

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Direct molecular imaging of Lymnaea stagnalis nervous tissue at subcellular spatial resolution by mass spectrometry.

29 September 2017

1 reference

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MALDI mass spectrometric imaging of biological tissue sections

29 September 2017

1 reference

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Methods to assess tissue-specific distribution and metabolism of drugs.

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Linear ion traps in mass spectrometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Molecular profiling of experimental Parkinson's disease: direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Molecularly imprinted TiO2-matrix-assisted laser desorption/ionization mass spectrometry for selectively detecting alpha-cyclodextrin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Integrating histology and imaging mass spectrometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Optimizing the MALDI-TOF-MS observation of peptides containing disulfide bonds

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Direct analysis of drug candidates in tissue by matrix‐assisted laser desorption/ionization mass spectrometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Direct tissue analysis using matrix-assisted laser desorption/ionization mass spectrometry: practical aspects of sample preparation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Real-time changes in 1H and 31P NMR spectra of malignant human mammary epithelial cells during treatment with the anti-inflammatory agent indomethacin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Profiling proteins from azoxymethane-induced colon tumors at the molecular level by matrix-assisted laser desorption/ionization mass spectrometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Organic ion imaging of biological tissue with secondary ion mass spectrometry and matrix-assisted laser desorption/ionization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Use of meso- tetrakis(pentafluorophenyl)porphyrin as a matrix for low molecular weight alkylphenol ethoxylates in laser desorption/ ionization time-of-flight mass spectrometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Molecular imaging of biological samples: localization of peptides and proteins using MALDI-TOF MS.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Matrix-assisted laser desorption ionization MS: a progress report

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Interspecies comparisons in toxicology: the utility and futility of plasma concentrations of the test substance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Analysis of chloroquine and metabolites directly from whole-body animal tissue sections by liquid extraction surface analysis (LESA) and tandem mass spectrometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Partial deficiency or short-term inhibition of 11beta-hydroxysteroid dehydrogenase type 1 improves cognitive function in aging mice.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

1,8-Bis(dimethylamino)naphthalene: a novel superbasic matrix for matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of fatty acids.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500365

Queries of MALDI-imaging global datasets identifying ion mass signatures associated with tissue compartments.

2 June 2018

1 reference

Choline kinase alpha in cancer prognosis and treatment

21 January 2018

1 reference

VAMAS interlaboratory study for desorption electrospray ionization mass spectrometry (DESI MS) intensity repeatability and constancy

21 January 2018

1 reference

2-hydrazino-1-methylpyridine: a highly sensitive derivatization reagent for oxosteroids in liquid chromatography-electrospray ionization-mass spectrometry

21 January 2018

1 reference

Forensic analysis of inks by imaging desorption electrospray ionization (DESI) mass spectrometry

21 January 2018

1 reference

Novel mass spectrometry imaging software assisting labeled normalization and quantitation of drugs and neuropeptides directly in tissue sections

21 January 2018

1 reference

MALDI mechanisms: wavelength and matrix dependence of the coupled photophysical and chemical dynamics model.

21 January 2018

1 reference

Electrospray tandem mass spectrometric study of alkyl 1-methylpyridinium ether derivatives of alcohols

21 January 2018

1 reference

9-Aminoacridine as a matrix for negative mode matrix-assisted laser desorption/ionization

21 January 2018

1 reference

Specific MALDI Imaging and Profiling for Biomarker Hunting and Validation: Fragment of the 11S Proteasome Activator Complex, Reg Alpha Fragment, Is a New Potential Ovary Cancer Biomarker

21 January 2018

1 reference

The desorption process in MALDI

21 January 2018

1 reference

12 December 2020

High throughput detection of tetracycline residues in milk using graphene or graphene oxide as MALDI-TOF MS matrix

1 reference

12 December 2020

Determination of elemental compositions from mass peak profiles of the molecular ion (m) and the m + 1 and m + 2 ions

1 reference

12 December 2020

Single cell matrix-assisted laser desorption/ionization mass spectrometry imaging

1 reference

12 December 2020

Hydrazinonicotinic acid as a novel matrix for highly sensitive and selective MALDI-MS analysis of oligosaccharides

1 reference

12 December 2020

Pharmacokinetics of the 13C labeled anticancer agent temozolomide detected in vivo by selective cross-polarization transfer

1 reference

12 December 2020

Autoradiography of cells double labeled with H-3 and C-14

1 reference

12 December 2020

Pharmacokinetic theory of cassette dosing in drug discovery screening

1 reference

12 December 2020

Detection, identification and structural investigation of biologically important compounds by secondary ion mass spectrometry

1 reference

12 December 2020

In vivo, in situ tissue analysis using rapid evaporative ionization mass spectrometry

1 reference

12 December 2020

Identifiers

DOI

10.1111/BPH.13135

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766375%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766375%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

25766375

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766375%20AND%20SRC:MED&resulttype=core&format=json