Human disease-causing mutations disrupt an N-C-terminal interaction and channel function of bestrophin 1 (Q28114975)

GOA release 2020-03-11

author name string

Zhiqiang Qu

1

1 reference

3 January 2017

Wei Cheng

2

1 reference

3 January 2017

Yuanyuan Cui

3

1 reference

3 January 2017

Yuanyuan Cui

4

1 reference

3 January 2017

Jie Zheng

Journal of Biological Chemistry

5

1 reference

3 January 2017

language of work or name

English

0 references

publication date

12 June 2009

1 reference

3 January 2017

1 reference

3 January 2017

284

1 reference

3 January 2017

24

1 reference

3 January 2017

16473–16481

1 reference

3 January 2017

Bestrophin, the product of the Best vitelliform macular dystrophy gene (VMD2), localizes to the basolateral plasma membrane of the retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

The vitelliform macular dystrophy protein defines a new family of chloride channels

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Structure-function analysis of the bestrophin family of anion channels

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Regulation of bestrophin Cl channels by calcium: role of the C terminus

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Bestrophin-2 is a candidate calcium-activated chloride channel involved in olfactory transduction

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Molecular physiology of bestrophins: multifunctional membrane proteins linked to best disease and other retinopathies

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1)

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

A short motif in the C-terminus of mouse bestrophin 3 [corrected] inhibits its activation as a Cl channel

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Bestrophin Cl- channels are highly permeable to HCO3-

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

The anion-selective pore of the bestrophins, a family of chloride channels associated with retinal degeneration

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

The best disease-linked Cl- channel hBest1 regulates Ca V 1 (L-type) Ca2+ channels via src-homology-binding domains

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Activation of bestrophin Cl- channels is regulated by C-terminal domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Large movement in the C terminus of CLC-0 chloride channel during slow gating

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Interplay between PIP3 and calmodulin regulation of olfactory cyclic nucleotide-gated channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Single Cl- channels activated by Ca2+ in Drosophila S2 cells are mediated by bestrophins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Focus on molecules: bestrophin (best-1).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Ca2+-activated Cl- current from human bestrophin-4 in excised membrane patches

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Hydrodynamic properties of porcine bestrophin-1 in Triton X-100.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

GFP-based FRET analysis in live cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca2+ channels in retinal pigment epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Looking chloride channels straight in the eye: bestrophins, lipofuscinosis, and retinal degeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Determinants of anion permeation in the second transmembrane domain of the mouse bestrophin-2 chloride channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Mouse bestrophin-2 is a bona fide Cl(-) channel: identification of a residue important in anion binding and conduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Ion channels for communication between and within cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Thermosensitive TRPV channel subunits coassemble into heteromeric channels with intermediate conductance and gating properties

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Two bestrophins cloned from Xenopus laevis oocytes express Ca(2+)-activated Cl(-) currents

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.002246

Gating of inward rectifier K+ channels by proton-mediated interactions of N- and C-terminal domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.002246

Interdomain interactions underlying activation of cyclic nucleotide-gated channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.002246

Gating rearrangements in cyclic nucleotide-gated channels revealed by patch-clamp fluorometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.002246

Disruption of an intersubunit interaction underlies Ca2+-calmodulin modulation of cyclic nucleotide-gated channels.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713530

Correlating visual acuity and electrooculogram recordings in Best's disease

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19372599

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chloride channel activity of bestrophin mutants associated with mild or late-onset macular degeneration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19372599