The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88 (Q28115132)

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

title

The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88 (English)

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3 January 2017

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William Harnett

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ORCID Public Data File 2021

Shabbir M. Moochhala

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object named as

Shabbir M. Moochhala

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3 January 2017

Padmam Puneet

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Mairi A. McGrath

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Hwee Kee Tay

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Lamyaa Al-Riyami

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Justyna Rzepecka

5

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Shazib Pervaiz

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Margaret M. Harnett

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Alirio J. Melendez

Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003.

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language of work or name

English

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publication date

1 April 2011

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12

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344–351

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4

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3 January 2017

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Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland.

21 January 2018

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The epidemiology of sepsis in the United States from 1979 through 2000

21 January 2018

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Severe sepsis and septic shock. Definitions, epidemiology, and clinical manifestations

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Innate immune recognition

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Structure and function of Toll receptors and their ligands

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Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

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Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy

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Endotoxaemia and serum tumour necrosis factor as prognostic markers in severe acute pancreatitis

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HMG-1 as a late mediator of endotoxin lethality in mice

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High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes

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Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62.

21 January 2018

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Inhibition of Fc epsilon RI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes

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Role of Toll-like receptor responses for sepsis pathogenesis

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Toll-like receptors in control of immunological autophagy.

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Multiple regulatory and effector roles of autophagy in immunity.

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

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Methods in mammalian autophagy research

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Risk and the efficacy of antiinflammatory agents: retrospective and confirmatory studies of sepsis

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A critical concentration of neutrophils is required for effective bacterial killing in suspension

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SphK1 regulates proinflammatory responses associated with endotoxin and polymicrobial sepsis

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Phospholipase D1 mediates TNFalpha-induced inflammation in a murine model of TNFalpha-induced peritonitis

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Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

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Autophagy negatively regulates keratinocyte inflammatory responses via scaffolding protein p62/SQSTM1.

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TIRAP: an adapter molecule in the Toll signaling pathway

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The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

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Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannan

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Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock

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TLR4/MD-2 monoclonal antibody therapy affords protection in experimental models of septic shock

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Therapeutic effects of TAK-242, a novel selective Toll-like receptor 4 signal transduction inhibitor, in mouse endotoxin shock model.

21 January 2018

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Discovery and development of toll-like receptor 4 (TLR4) antagonists: a new paradigm for treating sepsis and other diseases

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American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference

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A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62.

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Laser scanning cytometry: understanding the immune system in situ.

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Inverse Rap1 and phospho-ERK expression discriminate the maintenance phase of tolerance and priming of antigen-specific CD4+ T cells in vitro and in vivo.

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Antisense knockdown of sphingosine kinase 1 in human macrophages inhibits C5a receptor-dependent signal transduction, Ca2+ signals, enzyme release, cytokine production, and chemotaxis

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Anaphylatoxin signaling in human neutrophils. A key role for sphingosine kinase

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At the crossroads of necrosis and apoptosis: signaling to multiple cellular targets by HMGB1.

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12 December 2020

Bacterial lipopolysaccharides and innate immunity

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12 December 2020

The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee

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12 December 2020

Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways

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12 December 2020

Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae

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12 December 2020

TLR SIGNALING PATHWAY IN PATIENTS WITH SEPSIS

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12 December 2020

Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection

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12 December 2020

Cecal ligation and puncture

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12 December 2020

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis

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12 December 2020

Mediator modulation therapy of severe sepsis and septic shock: does it work?

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12 December 2020