Determinants of function and substrate specificity in human UDP-galactose 4'-epimerase (Q28115660)

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object named as

Judith L. Fridovich-Keil

1 reference

3 January 2017

Jenny M. Schulz

1

1 reference

3 January 2017

Alice L. Watson

2

1 reference

3 January 2017

Rebecca Sanders

3

1 reference

3 January 2017

Kerry L. Ross

Journal of Biological Chemistry

4

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3 January 2017

language of work or name

English

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publication date

30 July 2004

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3 January 2017

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3 January 2017

279

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31

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3 January 2017

32796–32803

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3 January 2017

Structure and function of enzymes of the Leloir pathway for galactose metabolism

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The enzymic conversion of glucosamine to galactosamine

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Reversible defects in O-linked glycosylation and LDL receptor expression in a UDP-Gal/UDP-GalNAc 4-epimerase deficient mutant

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Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active site

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1 reference

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O-glycosylation of the mucin type

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1 reference

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Characterization of two mutations associated with epimerase-deficiency galactosemia, by use of a yeast expression system for human UDP-galactose-4-epimerase

21 January 2018

1 reference

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Human UDP-galactose 4' epimerase (GALE) gene and identification of five missense mutations in patients with epimerase-deficiency galactosemia

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1 reference

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Identification and characterization of a mutation, in the human UDP-galactose-4-epimerase gene, associated with generalized epimerase-deficiency galactosemia

21 January 2018

1 reference

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Crystal structures of the oxidized and reduced forms of UDP-galactose 4-epimerase isolated from Escherichia coli

21 January 2018

1 reference

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Molecular structure of the NADH/UDP-glucose abortive complex of UDP-galactose 4-epimerase from Escherichia coli: implications for the catalytic mechanism

21 January 2018

1 reference

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High-resolution X-ray structure of UDP-galactose 4-epimerase complexed with UDP-phenol

21 January 2018

1 reference

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Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli

21 January 2018

1 reference

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Dramatic differences in the binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli

21 January 2018

1 reference

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Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase

21 January 2018

1 reference

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Cloning and characterisation of the UDP-glucose 4'-epimerase of Trypanosoma cruzi.

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Mechanistic roles of tyrosine 149 and serine 124 in UDP-galactose 4-epimerase from Escherichia coli

21 January 2018

1 reference

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Structural analysis of the Y299C mutant of Escherichia coli UDP-galactose 4-epimerase. Teaching an old dog new tricks

21 January 2018

1 reference

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Crystal structure of WbpP, a genuine UDP-N-acetylglucosamine 4-epimerase from Pseudomonas aeruginosa: substrate specificity in udp-hexose 4-epimerases

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1 reference

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New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

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Subcellular localization of galactose-1-phosphate uridylyltransferase in the yeast Saccharomyces cerevisiae

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Functional requirements of the active site position 185 in the human enzyme galactose-1-phosphate uridylyltransferase.

21 January 2018

1 reference

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Overexpression, purification, and characterization of yeast cyclophilins A and B

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Rapid cloning by homologous recombination in vivo

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Functional characterization of Gne (UDP-N-acetylglucosamine-4-epimerase), Wzz (chain length determinant), and Wzy (O-antigen polymerase) of Yersinia enterocolitica serotype O:8

21 January 2018

1 reference

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Genetic loci for coaggregation receptor polysaccharide biosynthesis in Streptococcus gordonii 38

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The O-antigen gene cluster of Escherichia coli O55:H7 and identification of a new UDP-GlcNAc C4 epimerase gene

21 January 2018

1 reference

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The role of UDP-glucose epimerase in carbohydrate metabolism of Arabidopsis.

21 January 2018

1 reference

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Genetics of galactose metabolism of Erwinia amylovora and its influence on polysaccharide synthesis and virulence of the fire blight pathogen

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The galE gene of Campylobacter jejuni is involved in lipopolysaccharide synthesis and virulence.

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Galactose metabolism is essential for the African sleeping sickness parasite Trypanosoma brucei

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

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The Bacillus subtilis Gne (GneA, GalE) protein can catalyse UDP-glucose as well as UDP-N-acetylglucosamine 4-epimerisation

21 January 2018

1 reference

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