Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage--mediator role of NO in leptin-induced PGE2, IL-6, and IL-8 production (Q28115730)

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English	Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage--mediator role of NO in leptin-induced PGE2, IL-6, and IL-8 production	scientific journal article

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scholarly article

1 reference

3 January 2017

Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage--mediator role of NO in leptin-induced PGE2, IL-6, and IL-8 production (English)

1 reference

3 January 2017

0 references

nitric oxide synthase 2

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

regulation of cytokine production involved in inflammatory response

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

Katriina Vuolteenaho

object named as

Katriina Vuolteenaho

1

1 reference

ORCID Public Data File 2021

author name string

Anna Koskinen

2

1 reference

3 January 2017

Meiju Kukkonen

3

1 reference

3 January 2017

Riina Nieminen

4

1 reference

3 January 2017

Unto Päivärinta

5

1 reference

3 January 2017

Teemu Moilanen

6

1 reference

3 January 2017

Eeva Moilanen

7

1 reference

3 January 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 January 2009

1 reference

3 January 2017

Mediators of Inflammation

1 reference

3 January 2017

2009

1 reference

3 January 2017

345838

1 reference

3 January 2017

copyright license

Creative Commons Attribution 3.0 Unported

1 January 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

1 reference

April 2022 Public Data File from Crossref

Positional cloning of the mouse obese gene and its human homologue

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20 March 2017

EULAR Recommendations 2003: an evidence based approach to the management of knee osteoarthritis: Report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT)

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Inhibitors of mitogen-activated protein kinases downregulate COX-2 expression in human chondrocytes

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20 March 2017

Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1

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20 March 2017

Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.

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20 March 2017

Leptin in gastroprotection induced by cholecystokinin or by a meal. Role of vagal and sensory nerves and nitric oxide

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Phosphatidylinositol 3-kinase, MEK-1 and p38 mediate leptin/interferon-gamma synergistic NOS type II induction in chondrocytes.

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The role of nitric oxide in osteoarthritis

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29 September 2017

Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention

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29 September 2017

Differential expression of leptin and leptin's receptor isoform (Ob-Rb) mRNA between advanced and minimally affected osteoarthritic cartilage; effect on cartilage metabolism

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29 September 2017

Role of leptin in immunity

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29 September 2017

Leptin stimulates proliferation and inhibits apoptosis in Barrett's esophageal adenocarcinoma cells by cyclooxygenase-2-dependent, prostaglandin-E2-mediated transactivation of the epidermal growth factor receptor and c-Jun NH2-terminal kinase activa

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29 September 2017

Leptin induces nitric oxide synthase type II in C6 glioma cells. Role for nuclear factor-kappaB in hormone effect

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29 September 2017

Intracellular signalling pathways activated by leptin

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29 September 2017

Leptin in immunology

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29 September 2017

The role of cytokines in cartilage matrix degeneration in osteoarthritis.

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29 September 2017

Cytokines as therapeutic targets for osteoarthritis

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29 September 2017

Evidence for a key role of leptin in osteoarthritis

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29 September 2017

Effects of leptin on the production of cytokines by cultured human endometrial stromal and epithelial cells

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29 September 2017

Synergistic induction of nitric oxide synthase type II: in vitro effect of leptin and interferon-gamma in human chondrocytes and ATDC5 chondrogenic cells

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29 September 2017

Leptin potentiates IFN-gamma-induced expression of nitric oxide synthase and cyclo-oxygenase-2 in murine macrophage J774A.1.

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29 September 2017

Leptin signalling

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29 September 2017

Human articular chondrocytes express functional leptin receptors

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29 September 2017

IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage

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29 September 2017

Human leptin stimulates proliferation and activation of human circulating monocytes

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29 September 2017

Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide.

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29 September 2017

Nitric oxide mediates interleukin-1 induced inhibition of glycosaminoglycan synthesis in rat articular cartilage

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2 June 2018

Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase.

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2 June 2018

Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis

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2 June 2018

Nitric oxide mediates leptin-induced luteinizing hormone-releasing hormone (LHRH) and LHRH and leptin-induced LH release from the pituitary gland.

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2 June 2018

Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target

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2 June 2018

Chondrocyte apoptosis induced by nitric oxide

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2 June 2018

Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis. Contribution of joint tissues to their articular production.

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21 January 2018

Regulation of the nitric oxide production resulting from the glucocorticoid-insensitive expression of iNOS in human osteoarthritic cartilage

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21 January 2018

Regulation of nitric oxide production in osteoarthritic and rheumatoid cartilage. Role of endogenous IL-1 inhibitors

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21 January 2018

Nitric oxide sustains nuclear factor kappaB activation in cytokine-stimulated chondrocytes

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21 January 2018

The in situ up-regulation of chondrocyte interleukin-1-converting enzyme and interleukin-18 levels in experimental osteoarthritis is mediated by nitric oxide

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21 January 2018

Animal models of arthritis in NOS2-deficient mice.

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21 January 2018

Leptin-induced nitric oxide production in white adipocytes is mediated through PKA and MAP kinase activation

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21 January 2018

Selective iNOS inhibitor 1400W enhances anti-catabolic IL-10 and reduces destructive MMP-10 in OA cartilage. Survey of the effects of 1400W on inflammatory mediators produced by OA cartilage as detected by protein antibody array.

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27 November 2018

Chondrocyte death in experimental osteoarthritis is mediated by MEK 1/2 and p38 pathways: role of cyclooxygenase-2 and inducible nitric oxide synthase

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27 November 2018

Nitric-Oxide Mediates Suppression of Cartilage Proteoglycan Synthesis by Interleukin-1

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27 November 2018

Systemic and local regulation of articular cartilage metabolism: Where does leptin fit in the puzzle?

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12 December 2020

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Neutrophil accumulation and activation by homologous IL-8 in rabbits. IL-8 induces destruction of cartilage and production of IL-1 and IL-1 receptor antagonist in vivo

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Pivotal role of nitric oxide in the control of blood pressure after leptin administration

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The Inhibitory Effect of Leptin on Angiotensin II-Induced Vasoconstriction in Vascular Smooth Muscle Cells Is Mediated via a Nitric Oxide-Dependent Mechanism

1 reference

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The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: possible role in osteoarthritic cartilage degradation

1 reference

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Inhibition of transforming growth factor beta production by nitric oxide-treated chondrocytes: implications for matrix synthesis

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Osteoarthritis or osteoarthrosis: the definition of inflammation becomes a semantic issue in the genomic era of molecular medicine

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Interleukin-6 and interleukin-8 levels in serum and synovial fluid of patients with osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

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Effects of exogenous IL-1 beta, TNF alpha, IL-6, IL-8 and LIF on cytokine production by human articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

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Nitric oxide and proteoglycan biosynthesis by human articular chondrocytes in alginate culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

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Serum leptin levels correlate with interleukin-6 levels and disease activity in patients with ankylosing spondylitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

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Nitric oxide activates metalloprotease enzymes in articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

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Leptin Promotes Differentiation and Survival of Human Dendritic Cells and Licenses Them for Th1 Priming

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

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Selective inhibition of inducible nitric oxide synthase reduces progression of experimental osteoarthritis in vivo: possible link with the reduction in chondrocyte apoptosis and caspase 3 level

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

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Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRbeta tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

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Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

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Selective inhibition of inducible nitric oxide synthase in experimental osteoarthritis is associated with reduction in tissue levels of catabolic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

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Identifiers

10.1155/2009/345838

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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