Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation (Q28115828)

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

GOA release 2020-03-11

1 reference

Exostosin glycosyltransferase 2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Marta Busse

4

0 references

Marion Kusche-Gullberg

7

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Maria Wilén

5

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Lena Kjellén

8

0 references

Jenny Presto

1

object named as

Jenny Presto

1 reference

4 January 2017

Maria Thuveson

2

1 reference

4 January 2017

Pernilla Carlsson

3

1 reference

4 January 2017

Inger Eriksson

Proceedings of the National Academy of Sciences of the United States of America

6

1 reference

4 January 2017

language of work or name

English

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publication date

25 March 2008

1 reference

4 January 2017

1 reference

4 January 2017

105

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4 January 2017

12

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4 January 2017

4751–4756

1 reference

4 January 2017

The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

In vitro polymerization of heparan sulfate backbone by the EXT proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Enzyme interactions in heparan sulfate biosynthesis: uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Association of EXT1 and EXT2, hereditary multiple exostoses gene products, in Golgi apparatus

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Cloning, Golgi localization, and enzyme activity of the full-length heparin/heparan sulfate-glucuronic acid C5-epimerase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

The mammalian unfolded protein response

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Heparan sulphate proteoglycans fine-tune mammalian physiology

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Order out of chaos: assembly of ligand binding sites in heparan sulfate

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Interactions between heparan sulfate and proteins: the concept of specificity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

The molecular diversity of glycosaminoglycans shapes animal development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Stem domains of heparan sulfate 6-O-sulfotransferase are required for Golgi localization, oligomer formation and enzyme activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Distinct effects on heparan sulfate structure by different active site mutations in NDST-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Biosynthesis of chondroitin/dermatan sulfate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Heparin and heparan sulfate biosynthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Effect of brefeldin A on heparan sulphate biosynthesis in Madin-Darby canine kidney cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Molecular diversity of heparan sulfate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Overexpression of different isoforms of glucosaminyl N-deacetylase/N-sulfotransferase results in distinct heparan sulfate N-sulfation patterns

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Presence of N-unsubstituted glucosamine units in native heparan sulfate revealed by a monoclonal antibody.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Biosynthesis of heparin. Purification of a 110-kDa mouse mastocytoma protein required for both glucosaminyl N-deacetylation and N-sulfation.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290785

Inhibitory effect of the mi transcription factor encoded by the mutant mi allele on GA binding protein-mediated transcript expression in mouse mast cells.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705807105

Regulated translation of heparan sulfate N-acetylglucosamine N-deacetylase/n-sulfotransferase isozymes by structured 5'-untranslated regions and internal ribosome entry sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705807105

Biosynthesis of chondroitin sulfate: interaction between xylosyltransferase and galactosyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705807105

Embryonic fibroblasts with a gene trap mutation in Ext1 produce short heparan sulfate chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705807105

Heparan sulfate structure in mice with genetically modified heparan sulfate production

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18337501

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential effect of brefeldin A on the biosynthesis of heparan sulfate and chondroitin/dermatan sulfate proteoglycans in rat ovarian granulosa cells in culture

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18337501

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0705807105

1 reference

4007847

ADS bibcode

2008PNAS..105.4751P

0 references

4007847

1 reference

1 reference

1 reference