The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade (Q28117353)

2

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4 January 2017

C. V. Paya

3

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4 January 2017

J. Moscat

4

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4 January 2017

R. D. Simari

5

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4 January 2017

G. J. Gores

Journal of Biological Chemistry

6

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4 January 2017

language of work or name

English

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publication date

30 June 2000

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4 January 2017

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275

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26

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20210–20216

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4 January 2017

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

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Dysregulation of apoptosis as a mechanism of liver disease: an overview.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909992199

Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909992199

The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

The activation of p38 and apoptosis by the inhibition of Erk is antagonized by the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

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The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

Cellular survival: a play in three Akts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909992199

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

1 reference

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Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

21 January 2018

1 reference

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Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport

21 January 2018

1 reference

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A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

Activation of IkappaB kinase beta by protein kinase C isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

Reconstitution of bile acid transport in the rat hepatoma McArdle RH-7777 cell line

21 January 2018

1 reference

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Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway

21 January 2018

1 reference

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Positioning atypical protein kinase C isoforms in the UV-induced apoptotic signaling cascade

21 January 2018

1 reference

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Gi proteins use a novel beta gamma- and Ras-independent pathway to activate extracellular signal-regulated kinase and mobilize AP-1 transcription factors in Jurkat T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

1 reference

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NFkappaB prevents apoptosis and liver dysfunction during liver regeneration

21 January 2018

1 reference

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Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

21 January 2018

1 reference

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Inhibition of TNF-induced apoptosis by NF-kappa B.

21 January 2018

1 reference

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Signal transduction and hepatocellular bile acid transport: cross talk between bile acids and second messengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

PI3K: downstream AKTion blocks apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

Synthetic lipid products of PI3-kinase which are added to culture medium prevent low K+-induced apoptosis of cerebellar granule neurons via Akt kinase activation.

21 January 2018

1 reference

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Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells

21 January 2018

1 reference

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Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

21 January 2018

1 reference

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Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

Apoptosis and hepatobiliary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909992199

Cholestasis in Rats induced by Taurolithocholate

21 January 2018

1 reference

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