Upregulation of synaptotagmin IV inhibits transmitter release in PC12 cells with targeted synaptotagmin I knockdown (Q28117788)

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20735850%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Upregulation of synaptotagmin IV inhibits transmitter release in PC12 cells with targeted synaptotagmin I knockdown (English)

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20735850%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

GOA release 2020-03-11

negative regulation of catecholamine secretion

1 reference

GOA release 2020-03-11

author

Jason B Papke

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20735850%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Johnnie M Moore-Dotson

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20735850%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Amy B Harkins

series ordinal

3

1 reference

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11 February 2020

publication date

24 August 2010

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20735850%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20735850%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

11

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20735850%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

104

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20735850%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

11 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2939654/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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20 March 2017

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20 March 2017

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Synaptotagmin IV is an immediate early gene induced by depolarization in PC12 cells and in brain

20 March 2017

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Synaptotagmin IV modulation of vesicle size and fusion pores in PC12 cells

20 March 2017

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Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses

20 March 2017

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20 March 2017

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Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4

20 March 2017

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Synaptotagmin IV is present at the Golgi and distal parts of neurites

20 March 2017

1 reference

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Synthesis degradation, and subcellular localization of synaptotagmin IV, a neuronal immediate early gene product

20 March 2017

1 reference

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The evolutionary pressure to inactivate. A subclass of synaptotagmins with an amino acid substitution that abolishes Ca2+ binding

20 March 2017

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Two synaptotagmin genes, Syt1 and Syt4, are differentially regulated in adult brain and during postnatal development following kainic acid-induced seizures

20 March 2017

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20 March 2017

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Loss of synaptotagmin IV results in a reduction in synaptic vesicles and a distortion of the Golgi structure in cultured hippocampal neurons

7 April 2017

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How does synaptotagmin trigger neurotransmitter release?

29 September 2017

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Stable RNA interference of synaptotagmin I in PC12 cells results in differential regulation of transmitter release.

29 September 2017

1 reference

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Stable gene silencing of synaptotagmin I in rat PC12 cells inhibits Ca2+-evoked release of catecholamine.

29 September 2017

1 reference

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29 September 2017

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29 September 2017

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Synaptotagmin IV: biochemistry, genetics, behavior, and possible links to human psychiatric disease

29 September 2017

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29 September 2017

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29 September 2017

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Deficits in memory and motor performance in synaptotagmin IV mutant mice

29 September 2017

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Activation of nicotinic acetylcholine receptors augments calcium channel-mediated exocytosis in rat pheochromocytoma (PC12) cells

29 September 2017

1 reference

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29 September 2017

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Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells

29 September 2017

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29 September 2017

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Different effects on fast exocytosis induced by synaptotagmin 1 and 2 isoforms and abundance but not by phosphorylation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Synaptotagmin IV overexpression inhibits depolarization-induced exocytosis in PC12 cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Intracellular Ca2+ pools in PC12 cells. A unique, rapidly exchanging pool is sensitive to both inositol 1,4,5-trisphosphate and caffeine-ryanodine

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Effect of forskolin on synaptotagmin IV protein trafficking in PC12 cells.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Reduced anxiety and depression-like behavior in synaptotagmin IV (-/-) mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Different domains of synaptotagmin control the choice between kiss-and-run and full fusion.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Nerve growth factor-dependent sorting of synaptotagmin IV protein to mature dense-core vesicles that undergo calcium-dependent exocytosis in PC12 cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Structure/function analysis of Ca2+ binding to the C2A domain of synaptotagmin 1

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Synaptotagmins I and IV promote transmitter release independently of Ca(2+) binding in the C(2)A domain

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

The C(2)B Ca(2+)-binding motif of synaptotagmin is required for synaptic transmission in vivo.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesicles

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

The C2B domain of synaptotagmin I is a Ca2+-binding module

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Quantitative and statistical analysis of the shape of amperometric spikes recorded from two populations of cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Differences in the ways sympathetic neurons and endocrine cells process, store, and secrete exogenous neuropeptides and peptide-processing enzymes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Synaptic function modulated by changes in the ratio of synaptotagmin I and IV.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Synaptotagmin: a membrane constituent of neuropeptide-containing large dense-core vesicles

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939654

Catecholamines are present in a synaptic-like microvesicle-enriched fraction from bovine adrenal medulla

27 November 2018

1 reference

12 December 2020

Effects of differentiation on neuropeptide-Y receptors and responses in rat pheochromocytoma cells

1 reference

12 December 2020

Modulation of intracellular calcium transients and dopamine release by neuropeptide Y in PC-12 cells

1 reference

12 December 2020

Extracellular ATP triggers two functionally distinct calcium signalling pathways in PC12 cells

1 reference

12 December 2020

Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C

1 reference

12 December 2020

Comparison of cytosolic Ca2+ and exocytosis responses from single rat and bovine chromaffin cells

1 reference

12 December 2020

Autoreceptor-induced inhibition of neuropeptide Y release from PC-12 cells is mediated by Y2 receptors

1 reference

12 December 2020

Expression of recombinant calcium channels support secretion in a mouse pheochromocytoma cell line

1 reference

12 December 2020

PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2202-11-104

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20735850%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 February 2020

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1471-2202-11-104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20735850%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

2 references

4 January 2017