Ku86 represses lethal telomere deletion events in human somatic cells (Q28119017)

4 January 2017

title

Ku86 represses lethal telomere deletion events in human somatic cells (English)

1 reference

Gene Ontology release 2020-05-02

4 January 2017

1 reference

Gene Ontology ID

GO:0090656

Telomeric repeat binding factor 2

1 reference

X-ray repair cross complementing 5

GOA release 2020-03-11

1 reference

negative regulation of t-circle formation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Yongbao Wang

series ordinal

1

1 reference

4 January 2017

Goutam Ghosh

series ordinal

2

1 reference

4 January 2017

Eric A. Hendrickson

series ordinal

3

1 reference

4 January 2017

language of work or name

English

0 references

publication date

28 July 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 January 2017

published in

1 reference

4 January 2017

volume

106

1 reference

4 January 2017

issue

30

1 reference

4 January 2017

page(s)

12430–12435

1 reference

Interaction of human Ku70 with TRF2

4 January 2017

cites work

1 reference

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Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

20 March 2017

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WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening

20 March 2017

1 reference

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Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

20 March 2017

1 reference

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Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres

20 March 2017

1 reference

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Homologous recombination in DNA repair and DNA damage tolerance

20 March 2017

1 reference

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Ku70, an essential gene, modulates the frequency of rAAV-mediated gene targeting in human somatic cells

20 March 2017

1 reference

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Telomere rapid deletion regulates telomere length in Arabidopsis thaliana

20 March 2017

1 reference

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The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Human Ku70/80 associates physically with telomerase through interaction with hTERT

20 March 2017

1 reference

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Homologous recombination generates T-loop-sized deletions at human telomeres

20 March 2017

1 reference

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Flexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate non-homologous DNA end joining: relevance to cancer, aging, and the immune system

20 March 2017

1 reference

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Strand-Specific Postreplicative Processing of Mammalian Telomeres

20 March 2017

1 reference

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A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.

20 March 2017

1 reference

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Mutations to Ku reveal differences in human somatic cell lines

29 September 2017

1 reference

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Telomere uncapping and alternative lengthening of telomeres

29 September 2017

1 reference

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Genetic knockouts and knockins in human somatic cells

29 September 2017

1 reference

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Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Ku: a multifunctional protein involved in telomere maintenance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Role of human Ku86 in telomere length maintenance and telomere capping

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Effects of double-strand break repair proteins on vertebrate telomere structure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Recombinational telomere elongation promoted by DNA circles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Maintenance of double-stranded telomeric repeats as the critical determinant for cell viability in yeast cells lacking Ku.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Ku86 is essential in human somatic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

A novel mechanism for telomere size control in Saccharomyces cerevisiae

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718384

Ku suppresses formation of telomeric circles and alternative telomere lengthening in Arabidopsis

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19581589

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0903362106

1 reference

release_aauvmyk4bfcv7mowdtwnfzvvia

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/aauvmyk4bfcv7mowdtwnfzvvia

mapped directly with Wikidata item

24 November 2022

based on heuristic

4729208

1 reference

1 reference

4729208

1 reference