Nedd4 E3 ubiquitin ligase promotes cell proliferation and autophagy (Q28119201)

4 January 2017

title

Nedd4 E3 ubiquitin ligase promotes cell proliferation and autophagy (English)

1 reference

NEDD4 E3 ubiquitin protein ligase

4 January 2017

main subject

1 reference

regulation of macroautophagy

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Yuyin Li

1

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

Li Zhang

2

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

Jie Zhou

3

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

Shenheng Luo

4

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

Rui Huang

5

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

Changcai Zhao

6

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

Aipo Diao

7

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

publication date

1 June 2015

1 reference

4 January 2017

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

volume

48

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

issue

3

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

page(s)

338-347

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

describes a project that uses

14 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6495840/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Polyubiquitin chains: polymeric protein signals

1 reference

The ubiquitin-proteasome pathway and pathogenesis of human diseases

21 January 2018

1 reference

Oncogenic aberrations of cullin-dependent ubiquitin ligases

21 January 2018

1 reference

The Nedd4-like family of E3 ubiquitin ligases and cancer

21 January 2018

1 reference

NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway

21 January 2018

1 reference

Nedd4 controls animal growth by regulating IGF-1 signaling

21 January 2018

1 reference

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

21 January 2018

1 reference

Ubiquitination regulates PTEN nuclear import and tumor suppression

21 January 2018

1 reference

The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization

21 January 2018

1 reference

21 January 2018

Lysosomes in cell death

1 reference

NF-kappaB protects from the lysosomal pathway of cell death.

21 January 2018

1 reference

Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.

21 January 2018

1 reference

Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion

21 January 2018

1 reference

Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis

21 January 2018

1 reference

The HECT family of E3 ubiquitin ligases: multiple players in cancer development

21 January 2018

1 reference

mTOR regulation of autophagy

21 January 2018

1 reference

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

21 January 2018

1 reference

Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis.

21 January 2018

1 reference

Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

21 January 2018

1 reference

Lysosomal release of cathepsin D precedes relocation of cytochrome c and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress

21 January 2018

1 reference

Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation.

21 January 2018

1 reference

21 January 2018

Autophagy and metabolism

1 reference

The double-edged sword of autophagy modulation in cancer

21 January 2018

1 reference

mTOR signaling in growth control and disease

21 January 2018

1 reference

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

21 January 2018

1 reference

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

21 January 2018

1 reference

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

21 January 2018

1 reference

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

21 January 2018

1 reference

Regulation of mTORC1 and its impact on gene expression at a glance

21 January 2018

1 reference

mTOR signaling at a glance

21 January 2018

1 reference

SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway

21 January 2018

1 reference

Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function

21 January 2018

1 reference

Nedd4 regulates ubiquitination and stability of the guanine-nucleotide exchange factor CNrasGEF

21 January 2018

1 reference

Nedd4.1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding

21 January 2018

1 reference

Nedd4 mediates ErbB4 JM-a/CYT-1 ICD ubiquitination and degradation in MDCK II cells

21 January 2018

1 reference

The E3 ubiquitin ligase NEDD4 negatively regulates HER3/ErbB3 level and signaling.

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25809873

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lysosomes as targets for cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25809873

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/CPR.12184

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495840&resulttype=core&format=json

14 May 2020

2 references

4 January 2017